Antihistamines and Their Effects
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Questions and Answers

What should a patient avoid when using nasal decongestants?

  • Taking them as prescribed
  • Using them during a cold
  • Using them continuously for more than 2 weeks (correct)
  • Mixing them with other nasal medications

Which of the following is a common treatment for xerostomia?

  • Brushing teeth more frequently
  • Consuming sour foods
  • Using over-the-counter artificial saliva products (correct)
  • Increasing caffeine intake

What is a key instruction for a patient using albuterol for an asthma attack?

  • Use it every hour as needed
  • Rinse the mouth after use (correct)
  • Use it only during exercise
  • Wait 5 minutes between puffs

What is a significant side effect associated with cholestyramine?

<p>Constipation (A)</p> Signup and view all the answers

When should a patient be cautious with propranolol?

<p>If experiencing dizziness occasionally (B)</p> Signup and view all the answers

Which medication is a bronchodilator that should not be given to asthma patients?

<p>Montelukast (D)</p> Signup and view all the answers

What is the maximum number of doses of nitroglycerin a patient can take in 15 minutes?

<p>3 doses (D)</p> Signup and view all the answers

What is the recommended action if atenolol is being considered for a patient with asthma?

<p>Avoid administering (B)</p> Signup and view all the answers

What is the primary action of Digoxin?

<p>Increases strength of myocardial contraction (A)</p> Signup and view all the answers

Which laboratory test is crucial for monitoring patients on Warfarin?

<p>PT/INR (D)</p> Signup and view all the answers

What should be monitored closely to prevent Digoxin toxicity?

<p>Potassium levels (D)</p> Signup and view all the answers

What condition is associated with Ceftriaxone when allergic to penicillin?

<p>Cross-reactivity (A)</p> Signup and view all the answers

Which side effect is most commonly associated with Aminoglycosides?

<p>Tinnitus (A)</p> Signup and view all the answers

What is a key instruction for taking Ferrous Sulfate with antibiotics?

<p>Take 2 hours before or after antibiotics (D)</p> Signup and view all the answers

What is a major adverse reaction associated with 1st generation antihistamines?

<p>Drowsiness (B)</p> Signup and view all the answers

What is the recommended action if a patient experiences an anaphylactic reaction?

<p>Call the healthcare provider and monitor vitals (C)</p> Signup and view all the answers

Which symptom indicates the use of antihistamines?

<p>Allergic conjunctivitis (A)</p> Signup and view all the answers

What is the purpose of the antidote Protamine Sulfate?

<p>To reverse Heparin effects (B)</p> Signup and view all the answers

What is a characteristic of 2nd generation antihistamines compared to 1st generation?

<p>Less drowsiness (C)</p> Signup and view all the answers

Which of the following is a use of antitussives?

<p>Relief of dry cough (D)</p> Signup and view all the answers

What is a common adverse reaction of centrally acting antitussives?

<p>Dizziness (C)</p> Signup and view all the answers

What type of cough is codeine indicated for?

<p>Unproductive cough (B)</p> Signup and view all the answers

Dextromethorphan is classified as what type of antitussive?

<p>Non-opioid antitussive (A)</p> Signup and view all the answers

Which agent is known to thin respiratory secretions?

<p>Guaifenesin (A)</p> Signup and view all the answers

What is the maximum daily dose of ibuprofen for adults?

<p>3200 mg (A)</p> Signup and view all the answers

Which medication should NOT be given to patients with heart failure?

<p>Adalimumab (B)</p> Signup and view all the answers

What is the major adverse reaction associated with using Fentanyl?

<p>Respiratory depression (B)</p> Signup and view all the answers

Which of the following medications is contraindicated for children due to the risk of Reye’s syndrome?

<p>Aspirin (B)</p> Signup and view all the answers

What should a nurse monitor for when a patient is taking Methotrexate?

<p>Complete blood count (CBC) (B)</p> Signup and view all the answers

Which symptom indicates salicylism, or aspirin toxicity?

<p>Tinnitus (C)</p> Signup and view all the answers

What dietary advice is important for patients taking Hydrochlorothiazide?

<p>Increase potassium intake (C)</p> Signup and view all the answers

When administering insulin, what is the recommended timeframe for feeding the patient?

<p>Within 30 minutes after administration (B)</p> Signup and view all the answers

Which medication is known for causing discoloration of urine to bright orange?

<p>Phenazopyridine (A)</p> Signup and view all the answers

What is the first-line treatment for hypotension?

<p>Hydrochlorothiazide (B)</p> Signup and view all the answers

Flashcards

Antihistamines - What is histamine?

Histamine is a chemical released by the body during allergic reactions and tissue injury, causing inflammation.

Antihistamines - How do they work?

Antihistamines block the effects of histamine, reducing inflammation and allergy symptoms.

Antihistamines - 1st Generation

First-generation antihistamines can cause drowsiness due to their effects on the brain.

Antihistamines - Uses

Antihistamines are used to relieve allergy symptoms like runny nose, sneezing, and itching.

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Antitussives - How do they work?

Antitussives suppress the cough reflex, reducing the urge to cough.

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Antitussives - When to use?

Antitussives are typically used for dry coughs, where there is little phlegm to bring up.

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Codeine - What is it?

Codeine is an opioid medication with antitussive properties, also used for pain relief.

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Expectorants - How do they work?

Expectorants thin mucus in the airway, making it easier to cough up.

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Overuse of Nasal Decongestants

Using nasal decongestants for longer than recommended (usually 2 weeks) can worsen congestion, a phenomenon known as 'rebound' congestion.

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Xerostomia

Xerostomia, also known as dry mouth, is a condition where the mouth doesn't produce enough saliva.

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Albuterol

Albuterol is a fast-acting bronchodilator used for emergency asthma attacks. It opens up the airways, making breathing easier.

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Montelukast

Montelukast is a long-acting bronchodilator, but it's NOT used for emergency asthma attacks. It's a preventative medication for asthma.

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SABA (Short-Acting Beta 2 Agonist)

SABAs like albuterol activate your fight-or-flight response, causing your airways to dilate and breathing to improve.

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Nitroglycerin

Nitroglycerin is a heart medication used to relieve chest pain (angina). It dilates blood vessels, improving blood flow to the heart.

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Verapamil

Verapamil is a heart medication that controls heart rate. It's given even if the heart rate is normal, as it helps maintain a stable rate.

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Propranolol vs Atenolol

Propranolol and Atenolol are beta-blockers, but Atenolol is NOT given to patients with asthma. They both lower blood pressure.

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Nitro Patch

A medication used to relieve chest pain by dilating blood vessels. Placed on the chest close to the heart, avoiding areas with hair.

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Heparin

An anticoagulant medication preventing blood clots. Requires monitoring of labs such as aPTT levels. Protamine Sulfate is the antidote in case of overdose.

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Coumadin/Warfarin

Anticoagulant medications that require monitoring of PT/INR levels. Vitamin K is the antidote for these medications.

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Digoxin

A medication that strengthens myocardial contractions, increases cardiac output and renal perfusion. Can cause toxicity with adverse effects like vision changes, bradycardia, arrhythmias, and 'yellow halos'. Avoid in patients with hypokalemia, as it can increase the risk of arrhythmias.

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Schedule B Controlled Substances

Drugs with the least potential for abuse compared to other controlled substances.

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Schedule 1 Controlled Substances

Drugs with the highest potential for abuse among controlled substances.

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Idiosyncrasy

An unusual or abnormal reaction to a medication, often unexpected.

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Super Infection

A new infection that occurs during or after treatment with antibiotics, often due to the disruption of normal bacterial flora.

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Aspirin - Max Dose

The maximum daily dose of aspirin is 3250mg.

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Aspirin - Uses

Aspirin is used for anticoagulation, pain, fever, inflammation; high doses decrease clotting.

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Aspirin - Risk

Aspirin is not for children due to the risk of Reye's syndrome, and it can cause stomach issues or GI upset.

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Ibuprofen - Max Dose

The maximum daily dose of ibuprofen is 3200mg.

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Ibuprofen - Risk

Ibuprofen can lead to kidney problems.

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Celecoxib - Unique Property

Celecoxib inhibits COX-2 without inhibiting COX-1, which means it doesn't cause GI upset.

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Celecoxib - Contraindication

Celecoxib is not used for CABGs due to increased risk of cardiovascular thrombosis, MI, and stroke.

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Salicylism

Salicylism is aspirin toxicity, resulting in symptoms like tinnitus, dizziness, and balance issues.

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Morphine - Monitoring

Morphine is an opioid analgesic that requires monitoring of vital signs, especially blood pressure.

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Naloxone (Narcan)

Naloxone is an opioid antagonist and an antidote for opioid overdose.

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Study Notes

Antihistamines

  • Histamine is produced in response to allergic reactions or tissue injury, triggering an inflammatory response.
  • First-generation antihistamines can cause drowsiness as a side effect.
  • Uses include relief from seasonal and perennial allergies, allergic rhinitis, conjunctivitis, and mild angioedema/urticaria. They may also be used to treat allergic reactions to drugs/blood/plasma, coughs, and Parkinson's-like symptoms, and nausea/vomiting.
  • Second-generation antihistamines (e.g., Loratadine) cause less drowsiness and fewer anticholinergic effects compared to first-generation.

Adverse Reactions

  • Central Nervous System: Drowsiness, sedation, and disturbed coordination are possible reactions.
  • Respiratory System: Dryness of the mouth, nose, and throat, plus thickening of bronchial secretions.
  • Other: Skin rashes (e.g., Urticaria) can occur as a potential drug allergy.

Antitussives

  • Centrally acting antitussives, like codeine, work by numbing stretch receptors in the respiratory passage, thus reducing coughs. They are only useful for nonproductive coughs.
  • Adverse reactions may include sedation, sweating, headaches, dizziness, lethargy, and confusion.
  • Drowsiness and other CNS depressants can have additive effects when used together, especially with codeine.
  • Dextromethorphan is a nonopioid antitussive, useful for symptomatic cough relief in cases of nonproductive coughs.

Expectorants

  • Expectorants (e.g., Guaifenesin) thin respiratory secretions, aiding in their removal.
  • They are often used to help with productive coughs, particularly associated with respiratory infections like sinusitis, asthma, bronchitis, and pharyngitis.

Nasal Decongestants

  • Overuse of nasal decongestants can lead to rebound nasal congestion.
  • Oxymetazoline (Afrin) is an example used for nasal congestion, reducing swelling and inflammation, and is used for treating the common cold, hay fever, sinusitis, and allergic rhinitis.

Bronchodilators

  • Bronchodilators (e.g., Albuterol) are used to treat bronchospasm and wheezing and are used for emergency asthma attacks.
  • Side effect: Wheezing, crackles, and constriction of bronchioles (lumens).

Other Medications

  • Montelukast (Singulair): A bronchodilator. Do not use in asthmatic patients.
  • SABA (short acting beta 2 agonist): Activates sympathetic nervous system, potentially causing high blood pressure, cardiac arrhythmias, and tachycardia.
  • Antihyperlipidemic Drugs: can increase cholesterol levels
  • Cholestyramine: Has constipation as a major side effect.
  • HDL and LDL are types of lipids (fats) in the blood. Good healthy fats (HDL) are helpful and bad unhealthy fats (LDL) should be reduced.

Specific Medication Notes

  • Propranolol, Atenolol: The patient needs to be educated about how to monitor their blood pressure. Never administer Atenolol if the patient has a history of asthma.
  • Nitroglycerin: Take 1 dose every 5 minutes, up to 3 doses total within 15 minutes.
  • Verapamil: Should be administered even if the heart rate is normal, as the drug is intended for maintaining heart rate, rather than directly affecting it.

Other

  • Schedule B controlled substances have lower abuse potential, while Schedule I controlled substances have the highest potential.
  • Idiosyncrasy refers to unusual or abnormal responses to medications.
  • SJS (Stevens-Johnson Syndrome): a severe skin reaction, with rashes, mouth sores, and skin lesions.
  • Sulfonamides: Used to treat UTIs; increase fluid intake to 2000ml a day. Watch for crystals in the urine.
  • Anaphylactic Shock: a severe allergic reaction.

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Description

This quiz covers the essential aspects of antihistamines, including their mechanisms, classifications, and common adverse reactions. It also explores the role of antitussives in treating coughs, helping you understand their uses and side effects. Test your knowledge on these important medications and their impact on health.

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