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Questions and Answers
What type of antigens do not require T cell helpers?
What type of antigens do not require T cell helpers?
- Peptides
- Polysaccharides (correct)
- LPS
- Proteins
Which cell provides help to B cells in Signal 2?
Which cell provides help to B cells in Signal 2?
- T FH cell (correct)
- Memory B cell
- Macrophage
- NK cell
Which signaling pathway provides Signal 2 to some B cells?
Which signaling pathway provides Signal 2 to some B cells?
- JAK/STAT signaling
- NF-kB signaling
- MAPK signaling
- TLR signaling (correct)
What is the role of IL21 in B cell biology?
What is the role of IL21 in B cell biology?
Which molecule cross-links on the BCR and is mentioned as a highly repetitive molecule?
Which molecule cross-links on the BCR and is mentioned as a highly repetitive molecule?
What happens when CD40 on B cells binds to CD40L on T FH cells?
What happens when CD40 on B cells binds to CD40L on T FH cells?
What is the rule of linked recognition between B and T FH cells?
What is the rule of linked recognition between B and T FH cells?
'Linked recognition' differs between T cells and B cells in that B cells can:
'Linked recognition' differs between T cells and B cells in that B cells can:
What is the function of plasma cells?
What is the function of plasma cells?
What happens to B cells that do not receive a survival signal?
What happens to B cells that do not receive a survival signal?
Where are B cells stored?
Where are B cells stored?
How do antigens enter the lymph node?
How do antigens enter the lymph node?
Which cell type retains antigens in the lymph node subcapsular sinus?
Which cell type retains antigens in the lymph node subcapsular sinus?
What receptors are expressed by B cells when binding antigens?
What receptors are expressed by B cells when binding antigens?
Which outcome is NOT triggered by phosphorylation of ITAM motifs on Iga and Igb?
Which outcome is NOT triggered by phosphorylation of ITAM motifs on Iga and Igb?
What is the function of activated Th-follicular helper (T FH) cells?
What is the function of activated Th-follicular helper (T FH) cells?
What is the main role of TFH cells in the context of B cell activation?
What is the main role of TFH cells in the context of B cell activation?
Which molecule provides Signal 1 in the activation of B cells?
Which molecule provides Signal 1 in the activation of B cells?
In the context of antibody production, what is the function of plasmablasts?
In the context of antibody production, what is the function of plasmablasts?
What type of immunity do antibodies promote through functions like Opsonization and Complement Activation?
What type of immunity do antibodies promote through functions like Opsonization and Complement Activation?
Which type of cytokines do TFH cells secrete to help activate B cells?
Which type of cytokines do TFH cells secrete to help activate B cells?
What is the main function of B cells in adaptive immunity?
What is the main function of B cells in adaptive immunity?
Which molecule allows TFH cells to interact with B cells through TCR signaling?
Which molecule allows TFH cells to interact with B cells through TCR signaling?
In the clonal selection theory, what happens to activated B cells?
In the clonal selection theory, what happens to activated B cells?
How do plasma cells differ from plasmablasts in antibody production?
How do plasma cells differ from plasmablasts in antibody production?
Which class of antibodies serves as a receptor on naive B cells?
Which class of antibodies serves as a receptor on naive B cells?
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