Podcast
Questions and Answers
What is the primary function of ergosterols in fungi?
What is the primary function of ergosterols in fungi?
- To facilitate the transport of nutrients into the cell
- To act as an energy source for cellular processes
- To maintain the fluidity and permeability of the cell membrane (correct)
- To provide structural integrity to the cell wall
Which class of antifungal drugs targets the enzyme CYP51 in the ergosterol biosynthesis pathway?
Which class of antifungal drugs targets the enzyme CYP51 in the ergosterol biosynthesis pathway?
- Echinocandins
- Polyenes
- Azoles (correct)
- Allylamines
What is the primary mechanism of action of polyene antifungal drugs?
What is the primary mechanism of action of polyene antifungal drugs?
- Inhibiting the enzyme CYP51 in the ergosterol biosynthesis pathway
- Inhibiting the conversion of squalene to lanosterol
- Disrupting the synthesis of β-D-glucan in the cell wall
- Binding to ergosterols and increasing membrane permeability (correct)
Which class of antifungal drugs inhibits the synthesis of β-D-glucan in the fungal cell wall?
Which class of antifungal drugs inhibits the synthesis of β-D-glucan in the fungal cell wall?
What is the primary mechanism of action of allylamine antifungal drugs?
What is the primary mechanism of action of allylamine antifungal drugs?
Which statement about antifungal drugs targeting ergosterols is correct?
Which statement about antifungal drugs targeting ergosterols is correct?