Antifungal Drugs and Fungi

To facilitate the transport of nutrients into the cell

To act as an energy source for cellular processes

To maintain the fluidity and permeability of the cell membrane (correct)

To provide structural integrity to the cell wall

Echinocandins

Polyenes

Azoles (correct)

Allylamines

Inhibiting the enzyme CYP51 in the ergosterol biosynthesis pathway

Inhibiting the conversion of squalene to lanosterol

Disrupting the synthesis of β-D-glucan in the cell wall

Binding to ergosterols and increasing membrane permeability (correct)

<p>Echinocandins</p> Signup and view all the answers

<p>Inhibiting the conversion of squalene to lanosterol</p> Signup and view all the answers

<p>They are selectively toxic to fungi due to targeting fungal ergosterols and not mammalian cholesterol</p> Signup and view all the answers