6 Questions
Which antidote is commonly used for Methemoglobinemia inducing agents like Nitrites and Nitrates?
Methylene blue
What is the antidote for Hydrogen sulfide poisoning?
Sodium bicarbonate
Which substance is NOT listed as an antidote in the text for any type of poisoning?
Lithium (Li)
What is the antidote for Lead (Pb) poisoning?
Dimercaprol
Which antidote is used for Ethylene glycol poisoning?
Ethanol
What antidote is administered for Arsenic poisoning?
Polystyrene sulfonate
Study Notes
Antidotes for Poisoning
- Anticholinergics (Atropine, Benztropine) can be treated with Physostigmine to counteract CNS depression caused by Diazepam
- Isoniazid (INH) poisoning can be treated with Vitamin B6 (Pyridoxine)
- Valproic acid overdose can be treated with L-carnitine
- Methotrexate (MTX) toxicity can be treated with Leucovorin
- Methemoglobinemia inducing agents (Nitrites, Nitrates) can be treated with Methylene blue
- Digoxin poisoning can be treated with Digibind or Digifab
- Beta blockers and Calcium channel blockers overdose can be treated with Calcium and Glucagon
- Opioids (Morphine, Heroin, Codeine, Fentanyl) overdose can be treated with Naloxone, Naltrexone, or Nalmefene
- Benzodiazepine (Diazepam, Zolpidem) overdose can be treated with Flumazenil
- TCA (Imipramine, Amitriptyline) poisoning can be treated with Sodium bicarbonate
- Warfarin and Heparin overdose can be treated with Vitamin K1 (Phyto-menadione) and Protamine sulfate
- Dabigatran overdose can be treated with Idarucizumab
- Thrombolytics (Streptokinase, urokinase, alteplase, Reteplase) bleeding can be treated with Aminocaproic acid and Tranexamic acid
- Nerve gases and Organophosphorus insecticides poisoning can be treated with Atropine followed by Pralidoxime (2-PAM)
- Carbamate insecticides poisoning can be treated with Atropine
- Cyanide gas poisoning can be treated with Sodium nitrite, Amyl nitrite, and Sodium thiosulfate
- Chlorine gas poisoning can be treated with Sodium bicarbonate and 100% O2
- Carbon monoxide poisoning can be treated with 100% O2
- Hydrogen sulfide poisoning can be treated with Sodium bicarbonate and 100% O2
- Methanol poisoning can be treated with Fomepizole, Ethanol, and Folic acid
- Ethylene glycol poisoning can be treated with Fomepizole, Ethanol, and Pyridoxine
- Iron (Fe) poisoning can be treated with Deferoxamine
- Lead (Pb) poisoning can be treated with CaEDTA and Dimercaprol
- Arsenic poisoning can be treated with DMSA and BAL
- Thallium poisoning can be treated with Prussian blue
- Mercury poisoning can be treated with BAL and DMSA
- Copper poisoning can be treated with BAL
- Lithium (Li) poisoning can be treated with Sodium bicarbonate and Polystyrene sulfonate
- Paracetamol/Acetaminophen overdose can be treated with N-Acetyl cysteine (NAC)
- Aspirin (Salicylic acid) overdose can be treated with Alkalinization (NaHCO3) and Octreotide
Test your knowledge on antidotes for various poisons and drug interactions. Topics include antidotes for anticholinergics, CNS depressants, methemoglobinemia inducing agents, cardiac medications, and more.
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