Podcast
Questions and Answers
Which antidote is commonly used for Methemoglobinemia inducing agents like Nitrites and Nitrates?
Which antidote is commonly used for Methemoglobinemia inducing agents like Nitrites and Nitrates?
- Digoxin
- Atropine
- Naloxone
- Methylene blue (correct)
What is the antidote for Hydrogen sulfide poisoning?
What is the antidote for Hydrogen sulfide poisoning?
- Sodium bicarbonate (correct)
- Deferoxamine
- D-Penicillamine
- Prussian blue
Which substance is NOT listed as an antidote in the text for any type of poisoning?
Which substance is NOT listed as an antidote in the text for any type of poisoning?
- Protamine sulfate
- Lithium (Li) (correct)
- Folic acid
- Flumazenil
What is the antidote for Lead (Pb) poisoning?
What is the antidote for Lead (Pb) poisoning?
Which antidote is used for Ethylene glycol poisoning?
Which antidote is used for Ethylene glycol poisoning?
What antidote is administered for Arsenic poisoning?
What antidote is administered for Arsenic poisoning?
Flashcards
Naloxone
Naloxone
A drug used to reverse the effects of opioid overdose by competing with opioid receptors for binding. It's a life-saving medication administered as an emergency treatment.
Pralidoxime (2-PAM)
Pralidoxime (2-PAM)
A treatment for poisoning caused by organophosphate insecticides and nerve gases. It reactivates the enzyme acetylcholinesterase that is inhibited by these toxins.
Deferoxamine
Deferoxamine
A treatment for poisoning caused by iron (Fe) overdose. It binds to iron ions, forming a stable complex that can be excreted in the urine.
N-Acetyl cysteine (NAC)
N-Acetyl cysteine (NAC)
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Fomepizole
Fomepizole
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Glucagon
Glucagon
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Study Notes
Antidotes for Poisoning
- Anticholinergics (Atropine, Benztropine) can be treated with Physostigmine to counteract CNS depression caused by Diazepam
- Isoniazid (INH) poisoning can be treated with Vitamin B6 (Pyridoxine)
- Valproic acid overdose can be treated with L-carnitine
- Methotrexate (MTX) toxicity can be treated with Leucovorin
- Methemoglobinemia inducing agents (Nitrites, Nitrates) can be treated with Methylene blue
- Digoxin poisoning can be treated with Digibind or Digifab
- Beta blockers and Calcium channel blockers overdose can be treated with Calcium and Glucagon
- Opioids (Morphine, Heroin, Codeine, Fentanyl) overdose can be treated with Naloxone, Naltrexone, or Nalmefene
- Benzodiazepine (Diazepam, Zolpidem) overdose can be treated with Flumazenil
- TCA (Imipramine, Amitriptyline) poisoning can be treated with Sodium bicarbonate
- Warfarin and Heparin overdose can be treated with Vitamin K1 (Phyto-menadione) and Protamine sulfate
- Dabigatran overdose can be treated with Idarucizumab
- Thrombolytics (Streptokinase, urokinase, alteplase, Reteplase) bleeding can be treated with Aminocaproic acid and Tranexamic acid
- Nerve gases and Organophosphorus insecticides poisoning can be treated with Atropine followed by Pralidoxime (2-PAM)
- Carbamate insecticides poisoning can be treated with Atropine
- Cyanide gas poisoning can be treated with Sodium nitrite, Amyl nitrite, and Sodium thiosulfate
- Chlorine gas poisoning can be treated with Sodium bicarbonate and 100% O2
- Carbon monoxide poisoning can be treated with 100% O2
- Hydrogen sulfide poisoning can be treated with Sodium bicarbonate and 100% O2
- Methanol poisoning can be treated with Fomepizole, Ethanol, and Folic acid
- Ethylene glycol poisoning can be treated with Fomepizole, Ethanol, and Pyridoxine
- Iron (Fe) poisoning can be treated with Deferoxamine
- Lead (Pb) poisoning can be treated with CaEDTA and Dimercaprol
- Arsenic poisoning can be treated with DMSA and BAL
- Thallium poisoning can be treated with Prussian blue
- Mercury poisoning can be treated with BAL and DMSA
- Copper poisoning can be treated with BAL
- Lithium (Li) poisoning can be treated with Sodium bicarbonate and Polystyrene sulfonate
- Paracetamol/Acetaminophen overdose can be treated with N-Acetyl cysteine (NAC)
- Aspirin (Salicylic acid) overdose can be treated with Alkalinization (NaHCO3) and Octreotide
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Description
Test your knowledge on antidotes for various poisons and drug interactions. Topics include antidotes for anticholinergics, CNS depressants, methemoglobinemia inducing agents, cardiac medications, and more.
