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Antidepressant Medications
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Antidepressant Medications

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Questions and Answers

What is the primary mechanism of action of Selective Serotonin Reuptake Inhibitors (SSRIs) in treating depression?

  • Blocking the reabsorption of serotonin
  • Increasing levels of dopamine in the brain
  • Decreasing levels of norepinephrine in the brain
  • Increasing levels of serotonin in the brain (correct)
  • Which type of antidepressant is known for its dietary restrictions due to interactions with tyramine-rich foods?

  • Monoamine Oxidase Inhibitors (MAOIs) (correct)
  • Norepinephrine and Dopamine Reuptake Inhibitors (NDRIs)
  • Selective Serotonin Reuptake Inhibitors (SSRIs)
  • Tricyclic Antidepressants (TCAs)
  • What is an example of an off-label use of antidepressant medications?

  • Treating anxiety disorders (correct)
  • Treating insomnia
  • Treating depression
  • Treating bipolar disorder
  • Which of the following is NOT a side effect of Tricyclic Antidepressants (TCAs)?

    <p>Dizziness</p> Signup and view all the answers

    What is the primary difference between Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs)?

    <p>SSRIs increase serotonin levels, while SNRIs increase serotonin and norepinephrine levels</p> Signup and view all the answers

    Which of the following antidepressant types increases levels of serotonin, norepinephrine, and dopamine?

    <p>Monoamine Oxidase Inhibitors (MAOIs)</p> Signup and view all the answers

    What is a common side effect of Selective Serotonin Reuptake Inhibitors (SSRIs)?

    <p>Nausea</p> Signup and view all the answers

    Which type of antidepressant is known for being introduced in the 1950s?

    <p>Monoamine Oxidase Inhibitors (MAOIs)</p> Signup and view all the answers

    Study Notes

    Selective Serotonin Reuptake Inhibitors (SSRIs)

    • Most commonly prescribed type of antidepressant
    • Work by increasing levels of serotonin in the brain
    • Examples:
      • Fluoxetine (Prozac)
      • Sertraline (Zoloft)
      • Paroxetine (Paxil)
      • Citalopram (Celexa)
      • Escitalopram (Lexapro)
    • Effective in treating depression, anxiety, and obsessive-compulsive disorder
    • Side effects:
      • Nausea, headache, insomnia, and sexual dysfunction

    Antidepressant Types

    • Monoamine Oxidase Inhibitors (MAOIs): increase levels of serotonin, norepinephrine, and dopamine
    • Tricyclic Antidepressants (TCAs): increase levels of serotonin and norepinephrine
    • Selective Serotonin Reuptake Inhibitors (SSRIs): increase levels of serotonin
    • Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs): increase levels of serotonin and norepinephrine
    • Norepinephrine and Dopamine Reuptake Inhibitors (NDRIs): increase levels of norepinephrine and dopamine

    Tricyclic Antidepressants (TCAs)

    • Older type of antidepressant, introduced in the 1950s
    • Work by increasing levels of serotonin and norepinephrine
    • Examples:
      • Amitriptyline (Elavil)
      • Imipramine (Tofranil)
      • Nortriptyline (Pamelor)
    • Effective in treating depression, anxiety, and insomnia
    • Side effects:
      • Dry mouth, constipation, blurred vision, and drowsiness

    Monoamine Oxidase Inhibitors (MAOIs)

    • Older type of antidepressant, introduced in the 1950s
    • Work by increasing levels of serotonin, norepinephrine, and dopamine
    • Examples:
      • Phenelzine (Nardil)
      • Tranylcypromine (Parnate)
    • Effective in treating depression, anxiety, and bipolar disorder
    • Side effects:
      • Dizziness, headache, insomnia, and weight gain
    • Dietary restrictions: must avoid foods high in tyramine (e.g. cheese, wine)

    Off-label Use

    • Using antidepressant medications for conditions other than depression
    • Examples:
      • Anxiety disorders (e.g. social anxiety disorder, post-traumatic stress disorder)
      • Insomnia and sleep disorders
      • Chronic pain management
      • Premenstrual dysphoric disorder
    • Off-label use requires careful consideration of risks and benefits, and close monitoring by a healthcare professional

    Antidepressant Medications

    • Most commonly prescribed type of antidepressant is Selective Serotonin Reuptake Inhibitors (SSRIs)
    • SSRIs increase levels of serotonin in the brain to treat depression, anxiety, and obsessive-compulsive disorder

    Types of Antidepressants

    • Monoamine Oxidase Inhibitors (MAOIs) increase levels of serotonin, norepinephrine, and dopamine
    • Tricyclic Antidepressants (TCAs) increase levels of serotonin and norepinephrine
    • Selective Serotonin Reuptake Inhibitors (SSRIs) increase levels of serotonin
    • Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs) increase levels of serotonin and norepinephrine
    • Norepinephrine and Dopamine Reuptake Inhibitors (NDRIs) increase levels of norepinephrine and dopamine

    SSRIs

    • Examples: Fluoxetine (Prozac), Sertraline (Zoloft), Paroxetine (Paxil), Citalopram (Celexa), Escitalopram (Lexapro)
    • Side effects: nausea, headache, insomnia, and sexual dysfunction

    Tricyclic Antidepressants (TCAs)

    • Older type of antidepressant, introduced in the 1950s
    • Examples: Amitriptyline (Elavil), Imipramine (Tofranil), Nortriptyline (Pamelor)
    • Side effects: dry mouth, constipation, blurred vision, and drowsiness

    Monoamine Oxidase Inhibitors (MAOIs)

    • Older type of antidepressant, introduced in the 1950s
    • Examples: Phenelzine (Nardil), Tranylcypromine (Parnate)
    • Dietary restrictions: must avoid foods high in tyramine (e.g. cheese, wine)
    • Side effects: dizziness, headache, insomnia, and weight gain

    Off-label Use

    • Using antidepressant medications for conditions other than depression
    • Examples: anxiety disorders, insomnia and sleep disorders, chronic pain management, premenstrual dysphoric disorder
    • Requires careful consideration of risks and benefits, and close monitoring by a healthcare professional

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    Learn about the different types of antidepressant medications, their mechanisms, and side effects. Includes Selective Serotonin Reuptake Inhibitors (SSRIs) and Monoamine Oxidase Inhibitors (MAOIs).

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