Podcast
Questions and Answers
Which factor is NOT typically associated with the etiology of deep vein thrombosis (DVT)?
Which factor is NOT typically associated with the etiology of deep vein thrombosis (DVT)?
- Venous stasis
- Endothelial damage
- Increased red blood cell production (correct)
- Hypercoagulability of blood
What term describes a blood clot that travels from its site of origin to another location in the body?
What term describes a blood clot that travels from its site of origin to another location in the body?
- Thrombus
- Embolus (correct)
- Stasis
- Plaque
If a patient's activated partial thromboplastin time (aPTT) result is significantly prolonged (e.g., 112 seconds), how should the heparin rate be adjusted?
If a patient's activated partial thromboplastin time (aPTT) result is significantly prolonged (e.g., 112 seconds), how should the heparin rate be adjusted?
- Decreased (correct)
- Discontinued immediately
- Maintained at the same level
- Increased
Which type of medication works by inhibiting cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2?
Which type of medication works by inhibiting cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2?
Hypoxemia related to pulmonary embolism would most likely directly result in which sign?
Hypoxemia related to pulmonary embolism would most likely directly result in which sign?
Which of the following is the main adverse effect associated with antiplatelet, anticoagulant, and fibrinolytic treatments?
Which of the following is the main adverse effect associated with antiplatelet, anticoagulant, and fibrinolytic treatments?
Which medication is used to reverse the effects of heparin or low molecular weight heparin (LMWH)?
Which medication is used to reverse the effects of heparin or low molecular weight heparin (LMWH)?
What is a common clinical sign indicative of hemorrhage?
What is a common clinical sign indicative of hemorrhage?
What is another term used to describe arterial thrombosis?
What is another term used to describe arterial thrombosis?
In patients with renal dysfunction, how should direct oral anticoagulants (DOACs) be managed?
In patients with renal dysfunction, how should direct oral anticoagulants (DOACs) be managed?
What laboratory test is typically used to measure the therapeutic range of heparin?
What laboratory test is typically used to measure the therapeutic range of heparin?
Which of the following should raise suspicion for heparin-induced thrombocytopenia (HIT)?
Which of the following should raise suspicion for heparin-induced thrombocytopenia (HIT)?
Which class of drugs functions by irreversibly inhibiting platelet aggregation through blocking ADP receptors?
Which class of drugs functions by irreversibly inhibiting platelet aggregation through blocking ADP receptors?
What is the role of plasmin?
What is the role of plasmin?
Rivaroxaban (Xarelto) and Apixaban (Eliquis) act by directly inhibiting?
Rivaroxaban (Xarelto) and Apixaban (Eliquis) act by directly inhibiting?
During primary hemostasis, what process occurs after platelets adhere to the site of vascular injury?
During primary hemostasis, what process occurs after platelets adhere to the site of vascular injury?
At therapeutic levels, how does warfarin affect vitamin K-dependent clotting factors?
At therapeutic levels, how does warfarin affect vitamin K-dependent clotting factors?
Which of the following best describes venous thrombosis that develops in areas of slow blood flow?
Which of the following best describes venous thrombosis that develops in areas of slow blood flow?
What is the purpose of 'bridging therapy' when initiating warfarin treatment?
What is the purpose of 'bridging therapy' when initiating warfarin treatment?
What standardized value is used to evaluate the effectiveness of warfarin?
What standardized value is used to evaluate the effectiveness of warfarin?
Flashcards
Virchow's Triad
Virchow's Triad
Venous stasis, endothelial damage, and hypercoagulability of blood.
Embolus
Embolus
Another term for traveling clot.
INR Increase
INR Increase
Occurs at therapeutic levels; warfarin decreases Vitamin K dependent factors by 30-50%.
Primary Hemostasis
Primary Hemostasis
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Hemophilia
Hemophilia
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INR
INR
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Renal dysfunction
Renal dysfunction
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Heparin/LMWH
Heparin/LMWH
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Thrombin
Thrombin
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NSAID
NSAID
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Dabigatran
Dabigatran
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Hypoxemia
Hypoxemia
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Clotting Factors
Clotting Factors
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Anti-Xa assay
Anti-Xa assay
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Thrombolytics
Thrombolytics
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Hemorrhage
Hemorrhage
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Venous thrombosis
Venous thrombosis
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Heparin
Heparin
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Study Notes
Across
- DVT etiology includes venous stasis, endothelial damage, and hypercoagulability of blood.
- A traveling clot is called an embolus.
- If a patient's aPTT result is 112, the heparin rate will be decreased.
- A medication that works by inhibiting the enzymes COX-1 and COX-2 is an NSAID.
- A sign that results from hypoxemia related to pulmonary embolisms is dyspnea.
- The main adverse effect of concern with antiplatelet, anticoagulant, or fibrinolytic treatment is bleeding.
- The reversal agent for heparin or LMWH medications is protamine sulfate.
- A sign of hemorrhage is ecchymosis.
- Arterial thrombosis can also be called a white clot.
- All DOACs should be adjusted for renal dysfunction.
- The therapeutic range of heparin is measured by using the aPTT.
Down
- Heparin-induced thrombocytopenia should be suspected if platelets fall rapidly during heparin treatment.
- A drug that works by irreversibly inhibiting platelet aggregation by blocking ADP receptors is clopidogrel.
- An enzyme that degrades the fibrin meshwork of a clot is plasmin.
- A DOAC that works by directly inhibiting thrombin is dabigatran.
- During primary hemostasis, platelets adhere, activate and aggregate.
- At therapeutic levels, warfarin decreases vitamin K dependent factors by 30-50%.
- Venous thrombosis occurs where blood flow is slow, known as stasis.
- Giving a short acting anticoagulant until warfarin is at steady state is bridging.
- Standardized value used for evaluating warfarin's effectiveness is INR.
- A genetic bleeding disorder caused by a lack of clotting proteins is hemophilia.
- All anticoagulants prevent the production of thrombin.
- Primary hemostasis is the formation of the platelet plug.
- A "Clot Buster" is a thrombolytic.
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