Anticoagulants: DOACs vs. Vitamin K Antagonists
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Questions and Answers

What does a normal thrombin time indicate?

  • Risk of thrombosis
  • Factor Xa inhibition
  • Absence of dabigatran (correct)
  • Presence of dabigatran

When is periprocedural bridging considered necessary?

  • Before any procedure
  • Only in select situations (correct)
  • In cases of high thrombosis risk
  • Always

What is the purpose of factor Xa inhibitors like andexanet alfa?

  • To monitor thrombin time
  • To manage acute major bleeding associated with factor Xa inhibitors (correct)
  • To treat chronic kidney disease
  • To induce major bleeding

Which anticoagulant is most prevalent in the United States according to the text?

<p>Warfarin (A)</p> Signup and view all the answers

What are the two main types of direct oral anticoagulants (DOACs) mentioned in the text?

<p>Dabigatran and rivaroxaban (B)</p> Signup and view all the answers

What is the primary purpose of understanding the mechanism and duration of action of anticoagulants as mentioned in the text?

<p>To know when to interrupt or resume therapy (B)</p> Signup and view all the answers

What is the estimated number of people in the United States taking anticoagulants?

<p>6 million (D)</p> Signup and view all the answers

Which type of anticoagulants has seen widespread adoption, as mentioned in the text?

<p>Direct oral anticoagulants (DOACs) (C)</p> Signup and view all the answers

Which committee published guidance on the periprocedural management of patients on chronic oral anticoagulant therapy?

<p>International Society on Thrombosis and Haemostasis Committee (B)</p> Signup and view all the answers

In what context do clinicians need to weigh the risks and benefits of temporarily stopping anticoagulants?

<p>For invasive procedures (B)</p> Signup and view all the answers

What factors should clinicians consider when determining the risk for thrombosis with mechanical heart valves?

<p>Type, position, and timing of placement of the valve (C)</p> Signup and view all the answers

How can stroke risk for atrial fibrillation (AF) be estimated according to the text?

<p>Using the CHA2DS2-VASc score (D)</p> Signup and view all the answers

When deciding on periprocedural management of anticoagulation, what should clinicians determine based on the patient's current medication?

<p>Whether the patient is taking a VKA or a DOAC (C)</p> Signup and view all the answers

What is a key challenge for clinicians and patients during the periprocedural period?

<p>Weighing the risks and benefits of temporarily stopping anticoagulants (D)</p> Signup and view all the answers

In the context of anticoagulation therapy, what is the significance of the landscape evolving with the widespread adoption of direct oral anticoagulants (DOACs)?

<p>Greater complexity in managing anticoagulation for invasive procedures (B)</p> Signup and view all the answers

What was the focus of the guidance document published by the SSC Subcommittee on Perioperative and Critical Care Thrombosis and Haemostasis?

<p>Standardizing reporting of procedural/surgical bleed risk and patient-specific thromboembolic risk (D)</p> Signup and view all the answers

What is a key consideration in assessing periprocedural anticoagulation management?

<p>Assessing the patient's bleeding risk for the procedure (C)</p> Signup and view all the answers

Which category of anticoagulants is not included in the major categories mentioned in the text?

<p>Antiplatelet agents (C)</p> Signup and view all the answers

Which anticoagulant mentioned in the text has a detailed summary of differences including onset of action and reversal strategies?

<p>Heparins (B)</p> Signup and view all the answers

What is one factor that clinicians should evaluate before making decisions about periprocedural anticoagulation?

<p>The bleeding risk associated with the procedure and the patient (B)</p> Signup and view all the answers

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