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Questions and Answers
What is the first clotting factor to decline in the presence of anticoagulants according to the text?
Which enzyme is required for the regeneration of hydroquinone form of vitamin K in the clotting process?
Which CYP enzyme metabolizes S-warfarin, the more active isomer of warfarin?
What is the main mechanism of action of oral anticoagulants like warfarin and phenindione?
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What is the major clinical consequence of phenindione usage among patients?
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Which factor has the longest half-life among the clotting factors discussed in the text?
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Which test is considered a better option for monitoring the effect of oral anticoagulants according to the text?
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What is the specific antidote mentioned for warfarin overdose in the text?
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Which specific clotting factors are affected by oral anticoagulants like warfarin and dicumarol?
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Why is warfarin contra-indicated during pregnancy according to the text?
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