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Anticoagulants Classification Quiz

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Questions and Answers

What is the first clotting factor to decline in the presence of anticoagulants according to the text?

Factor II

Protein C (correct)

Factor VII

Factor IX

Which enzyme is required for the regeneration of hydroquinone form of vitamin K in the clotting process?

Vitamin K epoxide reductase (VKOR) (correct)

Thrombin

Cytochrome P450

Vitamin K carboxylase

Which CYP enzyme metabolizes S-warfarin, the more active isomer of warfarin?

CYP3A4

CYP1A2

CYP2C9 (correct)

CYP2D6

What is the main mechanism of action of oral anticoagulants like warfarin and phenindione?

Inhibiting the activation of vitamin K dependent clotting factors Signup and view all the answers

What is the major clinical consequence of phenindione usage among patients?

Orange coloured urine Signup and view all the answers

Which factor has the longest half-life among the clotting factors discussed in the text?

Factor II Signup and view all the answers

Which test is considered a better option for monitoring the effect of oral anticoagulants according to the text?

International normalized ratio (INR) Signup and view all the answers

What is the specific antidote mentioned for warfarin overdose in the text?

Vitamin K1 Signup and view all the answers

Which specific clotting factors are affected by oral anticoagulants like warfarin and dicumarol?

Clotting factors II, VII, IX, and X Signup and view all the answers

Why is warfarin contra-indicated during pregnancy according to the text?

It causes fetal warfarin syndrome Signup and view all the answers