Cardio Lecture 4

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Which of the following medications is a direct, selective Factor Xa inhibitor?

Rivaroxaban (correct)

Apixaban

Warfarin

Dabigatran

What is the half-life of Factor IX, a vitamin K-dependent protein?

36 hours

24 hours (correct)

6 hours

60 hours

Which of the following is NOT a consideration for warfarin dosing?

Weight

Age

Ethnic background

Diet (correct)

What is the initial dosing range for warfarin in healthy outpatients?

5 mg Signup and view all the answers

Which of the following is a primary objective of this presentation?

Understanding the various indications for anticoagulation Signup and view all the answers

What is the purpose of the case discussion in this presentation?

To apply the knowledge gained from the presentation to a real-life scenario Signup and view all the answers

Which of the following is a dosing consideration for direct acting oral anticoagulants (DOACs)?

General dosing considerations for dabigatran, rivaroxaban, and apixaban Signup and view all the answers

Which type of heart valve requires lifelong warfarin?

Mechanical valve Signup and view all the answers

What is the recommended INR range for aortic mechanical valves without risk factors?

2.0 to 3.0 Signup and view all the answers

Which direct acting oral anticoagulant (DOAC) should never be used for anticoagulation of mechanical heart valves?

Dabigatran Signup and view all the answers

What is the approximate half-life of warfarin?

10-14 days Signup and view all the answers

Which of the following is a key factor that affects the INR and dosage requirements of warfarin?

Patient's weight Signup and view all the answers

What is the recommended dose of rivaroxaban for adult patients during the initial treatment of acute VTE?

15 mg BID Signup and view all the answers

Which of the following is NOT a special consideration for DOACs?

Laboratory monitoring Signup and view all the answers

What is the recommended dose of apixaban for adult patients during the first 7 days of VTE treatment?

5 mg BID Signup and view all the answers

According to the text, what is the recommended dose increase for Warfarin therapy in CASE 2?

8% Signup and view all the answers

Based on the information provided, what is the INR range goal for the patient in CASE 2?

2.0-3.0 Signup and view all the answers

Which of the following drugs can increase the catabolism of clotting factors?

Levothyroxine Signup and view all the answers

Which of the following antibiotics may increase the INR?

Moxifloxacin Signup and view all the answers

Which of the following is NOT a risk factor for venous thromboembolism (VTE)?

Minor trauma Signup and view all the answers

Which of the following is the preferred treatment for venous thromboembolism (VTE)?

Rivaroxaban or apixaban alone Signup and view all the answers

Which of the following is a risk factor for stroke in patients with atrial fibrillation/flutter?

Hypertension Signup and view all the answers

What is the recommended anticoagulation therapy for stroke prevention in patients with atrial fibrillation/flutter?

Warfarin (TTR >70% in range 2.0-3.0) Signup and view all the answers