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Anticoagulant Drugs and Their Mechanism of Action

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Anticoagulant Drugs and Their Mechanism of Action

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Questions and Answers

How does TXA2 affect calcium levels?

Increases calcium levels

What is the role of prostacyclin in platelet aggregation?

Inhibits platelet aggregation

What is the main adverse effect of aspirin in children under 12 years old?

Reye's syndrome and ischemic stroke

How does dipyridamole affect cAMP levels?

Increases cAMP levels Signup and view all the answers

What is the mechanism of action of clopidogrel in platelet aggregation?

Inhibits the activation of the Glycoprotein 2b3a receptor Signup and view all the answers

What is the target of abciximab in platelets?

Glycoprotein 2b3a receptor Signup and view all the answers

What is the indication for using Vit K antagonists?

Prophylaxis and treatment of DVT, PE, prophylaxis of embolization in atrial fibrillation and rheumatic disease, patient with prosthetic heart valves Signup and view all the answers

How does Heparin work in the body?

Heparin activates antithrombin III, which limits blood clotting by inactivating thrombin and factor X. Signup and view all the answers

What is the main use of Hirudins?

Used in patients with type 2 heparin-induced thrombocytopenia. Signup and view all the answers

What are the potential adverse effects associated with Vit K antagonists?

Cerebral thrombosis, peripheral arterial occlusion, peptic ulcers, hypertension, pregnancy hemorrhage Signup and view all the answers

Name a side effect associated with Heparin use.

Skin necrosis Signup and view all the answers

What is the mechanism of action of the drug used for prevention and treatment of myocardial infarction and ischemic stroke?

Blocks the synthesis of Thromboxane A2 from Arachidonic acid in platelets Signup and view all the answers