12 Questions
How does TXA2 affect calcium levels?
Increases calcium levels
What is the role of prostacyclin in platelet aggregation?
Inhibits platelet aggregation
What is the main adverse effect of aspirin in children under 12 years old?
Reye's syndrome and ischemic stroke
How does dipyridamole affect cAMP levels?
Increases cAMP levels
What is the mechanism of action of clopidogrel in platelet aggregation?
Inhibits the activation of the Glycoprotein 2b3a receptor
What is the target of abciximab in platelets?
Glycoprotein 2b3a receptor
What is the indication for using Vit K antagonists?
Prophylaxis and treatment of DVT, PE, prophylaxis of embolization in atrial fibrillation and rheumatic disease, patient with prosthetic heart valves
How does Heparin work in the body?
Heparin activates antithrombin III, which limits blood clotting by inactivating thrombin and factor X.
What is the main use of Hirudins?
Used in patients with type 2 heparin-induced thrombocytopenia.
What are the potential adverse effects associated with Vit K antagonists?
Cerebral thrombosis, peripheral arterial occlusion, peptic ulcers, hypertension, pregnancy hemorrhage
Name a side effect associated with Heparin use.
Skin necrosis
What is the mechanism of action of the drug used for prevention and treatment of myocardial infarction and ischemic stroke?
Blocks the synthesis of Thromboxane A2 from Arachidonic acid in platelets
This quiz covers the indications, routes of administration, and mechanisms of action of anticoagulant drugs such as Vitamin K antagonists, Heparin, and LMWH. Learn about the prophylaxis and treatment of DVT, PE, atrial fibrillation, and more.
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