Anticholinesterases
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Questions and Answers

What do anticholinesterases inhibit?

  • Accumulation of ACh at muscarinic and nicotinic sites
  • Metabolism of ACh
  • Hydrolysis of ACh (correct)
  • Binding of ACh to muscarinic and nicotinic sites

    • Why are anticholinesterases called indirectly acting cholinergic drugs?

  • They bind to both anionic and esteratic sites of cholinesterase
  • They bind to the anionic site of ChE
  • They cause ACh to accumulate at muscarinic and nicotinic sites (correct)
  • They prevent the metabolism of ACh

    • What is the duration of action of Edrophonium?

  • 5 minutes
  • 15 minutes
  • 20 minutes
  • 8-10 minutes (correct)

    • What do Carbamates bind to?

    <p>Both anionic and esteratic sites of cholinesterase</p> Signup and view all the answers

    What happens when ACh binds to anionic and esteratic sites of cholinesterase?

    <p>Undergoes rapid hydrolysis</p> Signup and view all the answers

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