Podcast
Questions and Answers
What are the goals of treatment for cancer?
What are the goals of treatment for cancer?
- Prevention and containment of tumor growth
- Management of symptoms and improvement of quality of life
- Control of disease and prevention of relapse (correct)
- Promotion of tumor growth and metastasis
What is the recommended approach for minimizing resistance and relapse in cancer treatment?
What is the recommended approach for minimizing resistance and relapse in cancer treatment?
- Long-term, single therapy with low dosage
- Alternative medicine and dietary supplements
- High dosage of a single drug with continuous scheduling
- Combination therapy with intermittent scheduling (correct)
How is the dosage of anticancer drugs determined?
How is the dosage of anticancer drugs determined?
- By the patient's age and gender
- Based on tumor type and location
- According to the patient's weight and height
- Based on the patient's body surface (correct)
What are the common toxicities associated with anticancer drugs?
What are the common toxicities associated with anticancer drugs?
Combination therapy is less successful in cancer treatment.
Combination therapy is less successful in cancer treatment.
The goals of cancer treatment include cure and control of disease.
The goals of cancer treatment include cure and control of disease.
Resistance and relapse can be minimized by short term, intensive, intermittent therapy and combination.
Resistance and relapse can be minimized by short term, intensive, intermittent therapy and combination.
Anticancer drugs only cause minor side effects like mild nausea.
Anticancer drugs only cause minor side effects like mild nausea.
Which phase of the cell cycle do antimetabolites specifically target?
Which phase of the cell cycle do antimetabolites specifically target?
What is the primary mode of action of antimetabolites in interfering with cancer cell growth?
What is the primary mode of action of antimetabolites in interfering with cancer cell growth?
Which compound is an example of an antimetabolite drug used in cancer treatment?
Which compound is an example of an antimetabolite drug used in cancer treatment?
What is the primary mode of action of Methotrexate (MTX) as an anticancer drug?
What is the primary mode of action of Methotrexate (MTX) as an anticancer drug?
Which route of administration is used for Methotrexate (MTX)?
Which route of administration is used for Methotrexate (MTX)?
How is renal toxicity associated with Methotrexate (MTX) minimized?
How is renal toxicity associated with Methotrexate (MTX) minimized?
What are the common adverse effects associated with Methotrexate (MTX) as an anticancer drug?
What are the common adverse effects associated with Methotrexate (MTX) as an anticancer drug?
Methotrexate is an antimetabolite drug that affects the activation of folic acid.
Methotrexate is an antimetabolite drug that affects the activation of folic acid.
Methotrexate inhibits de novo purine nucleotide synthesis.
Methotrexate inhibits de novo purine nucleotide synthesis.
Methotrexate is primarily excreted via feces.
Methotrexate is primarily excreted via feces.
The adverse effects of Methotrexate may include mucositis and myelosuppression.
The adverse effects of Methotrexate may include mucositis and myelosuppression.
What is the primary mode of action of 5 Fluorouracil (5 FU) as an anticancer drug?
What is the primary mode of action of 5 Fluorouracil (5 FU) as an anticancer drug?
For which type of cancer is 5 Fluorouracil (5 FU) commonly used?
For which type of cancer is 5 Fluorouracil (5 FU) commonly used?
What is the mechanism of action of 5 Fluorouracil (5 FU) that results in thymineless death?
What is the mechanism of action of 5 Fluorouracil (5 FU) that results in thymineless death?
5 Fluorouracil (5 FU) inhibits thymidylate synthase, leading to thymineless death.
5 Fluorouracil (5 FU) inhibits thymidylate synthase, leading to thymineless death.
5 Fluorouracil (5 FU) is commonly used in the treatment of pancreatic cancer.
5 Fluorouracil (5 FU) is commonly used in the treatment of pancreatic cancer.
The primary mode of action of antimetabolites is inhibiting DNA synthesis and function.
The primary mode of action of antimetabolites is inhibiting DNA synthesis and function.
What is the primary mode of action of 5 Fluorouracil (5 FU) as an anticancer drug?
What is the primary mode of action of 5 Fluorouracil (5 FU) as an anticancer drug?
How is elevated dihdropyrimidine dehydrogenase (DPD) activity likely to affect the bioavailability of 5 Fluorouracil (5 FU)?
How is elevated dihdropyrimidine dehydrogenase (DPD) activity likely to affect the bioavailability of 5 Fluorouracil (5 FU)?
Which adverse effect is commonly associated with 5 Fluorouracil (5 FU) as an anticancer drug?
Which adverse effect is commonly associated with 5 Fluorouracil (5 FU) as an anticancer drug?
What is the primary mode of action of doxorubicin as an anticancer drug?
What is the primary mode of action of doxorubicin as an anticancer drug?
How is doxorubicin primarily administered to patients?
How is doxorubicin primarily administered to patients?
What is the mechanism of action of bleomycin as an anticancer drug?
What is the mechanism of action of bleomycin as an anticancer drug?
Which type of cancer is doxorubicin commonly used to treat?
Which type of cancer is doxorubicin commonly used to treat?
Doxorubicin primarily acts by binding to DNA and inducing single and double strand DNA breaks.
Doxorubicin primarily acts by binding to DNA and inducing single and double strand DNA breaks.
Anticancer bleomycin is cell cycle specific in their mode of action.
Anticancer bleomycin is cell cycle specific in their mode of action.
Bleomycin inhibits topoisomerases I and II in cancer cells.
Bleomycin inhibits topoisomerases I and II in cancer cells.
Doxorubicin is primarily administered orally to patients.
Doxorubicin is primarily administered orally to patients.
What is the primary route of excretion for Doxorubicin?
What is the primary route of excretion for Doxorubicin?
Which adverse effect is specifically associated with Doxorubicin?
Which adverse effect is specifically associated with Doxorubicin?
What is the primary mode of metabolism for Doxorubicin?
What is the primary mode of metabolism for Doxorubicin?
What is the primary route of excretion for Bleomycin?
What is the primary route of excretion for Bleomycin?
Which adverse effect is commonly associated with Bleomycin as an anticancer drug?
Which adverse effect is commonly associated with Bleomycin as an anticancer drug?
What is the primary mode of action of Bleomycin as an anticancer drug?
What is the primary mode of action of Bleomycin as an anticancer drug?
Bleomycin is primarily excreted in feces.
Bleomycin is primarily excreted in feces.
The adverse effects of Bleomycin may include pulmonary fibrosis.
The adverse effects of Bleomycin may include pulmonary fibrosis.
Bleomycin inhibits topoisomerases I and II in cancer cells.
Bleomycin inhibits topoisomerases I and II in cancer cells.
What is the primary mode of action of alkylating agents as anticancer drugs?
What is the primary mode of action of alkylating agents as anticancer drugs?
Which type of cancer cells do alkylating agents affect?
Which type of cancer cells do alkylating agents affect?
What adverse effect is commonly associated with alkylating agents as anticancer drugs?
What adverse effect is commonly associated with alkylating agents as anticancer drugs?
Alkylating agents primarily affect resting cells rather than cycling cells.
Alkylating agents primarily affect resting cells rather than cycling cells.
Bleomycin is primarily excreted via feces.
Bleomycin is primarily excreted via feces.
Combination therapy has been found to be less successful in cancer treatment.
Combination therapy has been found to be less successful in cancer treatment.
What adverse effect is commonly associated with alkylating agents as anticancer drugs?
What adverse effect is commonly associated with alkylating agents as anticancer drugs?
What is the primary route of excretion for Cyclophosphamide metabolites?
What is the primary route of excretion for Cyclophosphamide metabolites?
How is hemorrhagic cystitis, a common adverse effect of Cyclophosphamide, minimized?
How is hemorrhagic cystitis, a common adverse effect of Cyclophosphamide, minimized?
Cyclophosphamide can be administered both orally and intravenously with the same efficacy.
Cyclophosphamide can be administered both orally and intravenously with the same efficacy.
The adverse effects of Cyclophosphamide may include alopecia and amenorrhea.
The adverse effects of Cyclophosphamide may include alopecia and amenorrhea.
The primary route of excretion for Bleomycin is through feces.
The primary route of excretion for Bleomycin is through feces.
What are the common adverse effects associated with Lomustine as an anticancer drug?
What are the common adverse effects associated with Lomustine as an anticancer drug?
How is renal toxicity associated with Carmustine minimized?
How is renal toxicity associated with Carmustine minimized?
What is the primary mode of action of Nitrosoureas like carmustine and lomustine as anticancer drugs?
What is the primary mode of action of Nitrosoureas like carmustine and lomustine as anticancer drugs?
Which alkylating agent is excreted in urine and has metabolites that are also active, such as streptozocin?
Which alkylating agent is excreted in urine and has metabolites that are also active, such as streptozocin?
What is the primary mode of action of Nitrosoureas like carmustine and lomustine as anticancer drugs?
What is the primary mode of action of Nitrosoureas like carmustine and lomustine as anticancer drugs?
How is renal toxicity associated with Carmustine minimized?
How is renal toxicity associated with Carmustine minimized?
What is the primary route of administration for oxaliplatin?
What is the primary route of administration for oxaliplatin?
Which type of cancer is carboplatin commonly used to treat?
Which type of cancer is carboplatin commonly used to treat?
How is oxaliplatin excreted from the body?
How is oxaliplatin excreted from the body?
Alkylating agents like cisplatin, carboplatin, and oxaliplatin are excreted through the feces.
Alkylating agents like cisplatin, carboplatin, and oxaliplatin are excreted through the feces.
Oxaliplatin can be administered intravenously (IV) and intraperitoneally (IP).
Oxaliplatin can be administered intravenously (IV) and intraperitoneally (IP).
Carboplatin is used when the patient is prone to neuro or ototoxicity.
Carboplatin is used when the patient is prone to neuro or ototoxicity.
Which alkylating agent is specifically associated with cold-induced peripheral neuropathy?
Which alkylating agent is specifically associated with cold-induced peripheral neuropathy?
Which alkylating agent is primarily known for its mild gastrointestinal toxicity and rare nephrotoxicity, neurotoxicity, and ototoxicity?
Which alkylating agent is primarily known for its mild gastrointestinal toxicity and rare nephrotoxicity, neurotoxicity, and ototoxicity?
Which alkylating agent is associated with adverse effects such as nausea/vomiting, myelosuppression, neurotoxicity, nephrotoxicity, and ototoxicity?
Which alkylating agent is associated with adverse effects such as nausea/vomiting, myelosuppression, neurotoxicity, nephrotoxicity, and ototoxicity?
What is the primary mode of action of vinca alkaloids and taxane family as anticancer drugs?
What is the primary mode of action of vinca alkaloids and taxane family as anticancer drugs?
How are vinca alkaloids (vincristine (VX), vinblastine (VBL), vinorelbine (VRB)) and taxane family (paclitaxel) commonly administered?
How are vinca alkaloids (vincristine (VX), vinblastine (VBL), vinorelbine (VRB)) and taxane family (paclitaxel) commonly administered?
What is the primary route of administration for microtubule inhibitors like paclitaxel and vinblastine?
What is the primary route of administration for microtubule inhibitors like paclitaxel and vinblastine?
Vinca alkaloids and taxane family drugs are commonly administered through the oral route.
Vinca alkaloids and taxane family drugs are commonly administered through the oral route.
Anticancer drugs primarily cause only minor side effects like mild nausea.
Anticancer drugs primarily cause only minor side effects like mild nausea.
Methotrexate is primarily excreted via feces.
Methotrexate is primarily excreted via feces.
What is the primary mode of action of vinca alkaloids as anticancer drugs?
What is the primary mode of action of vinca alkaloids as anticancer drugs?
Which adverse effect is specifically associated with vinca alkaloids as anticancer drugs?
Which adverse effect is specifically associated with vinca alkaloids as anticancer drugs?
How are vinca alkaloids metabolized and eliminated from the body?
How are vinca alkaloids metabolized and eliminated from the body?
Vinca alkaloids primarily inhibit tubulin polymerization to induce mitosis in cells.
Vinca alkaloids primarily inhibit tubulin polymerization to induce mitosis in cells.
Anticancer drugs like Vinca alkaloids are primarily metabolized in the kidneys.
Anticancer drugs like Vinca alkaloids are primarily metabolized in the kidneys.
The common adverse effects of Vinca alkaloids include phlebitis, nausea, and vomiting.
The common adverse effects of Vinca alkaloids include phlebitis, nausea, and vomiting.
What is the primary route of excretion for vinblastine (VBL) among the listed options?
What is the primary route of excretion for vinblastine (VBL) among the listed options?
What is the most common adverse effect associated with vinorelbine (VRB) among the listed options?
What is the most common adverse effect associated with vinorelbine (VRB) among the listed options?
Which type of cancer is vincristine (VX) primarily used to treat from the given options?
Which type of cancer is vincristine (VX) primarily used to treat from the given options?
Which type of cancer is vinorelbine (VRB) commonly used to treat?
Which type of cancer is vinorelbine (VRB) commonly used to treat?
What type of neoplasms are microtubule inhibitors like VX primarily used for?
What type of neoplasms are microtubule inhibitors like VX primarily used for?
Metastatic testicular carcinoma and systemic Hodgkin and non-Hodgkin lymphomas are commonly treated using which drug?
Metastatic testicular carcinoma and systemic Hodgkin and non-Hodgkin lymphomas are commonly treated using which drug?
What is the primary mode of action of microtubule inhibitors like docetaxel and paclitaxel?
What is the primary mode of action of microtubule inhibitors like docetaxel and paclitaxel?
What is the primary route of metabolism for taxane family drugs like docetaxel and paclitaxel?
What is the primary route of metabolism for taxane family drugs like docetaxel and paclitaxel?
Which adverse effect is commonly associated with microtubule inhibitors like docetaxel and paclitaxel?
Which adverse effect is commonly associated with microtubule inhibitors like docetaxel and paclitaxel?
What is the mechanism of action of Camptothecins such as irinotecan and topotecan?
What is the mechanism of action of Camptothecins such as irinotecan and topotecan?
For which condition is topotecan commonly used?
For which condition is topotecan commonly used?
In combination therapy, how is irinotecan primarily used for the treatment of colorectal carcinoma?
In combination therapy, how is irinotecan primarily used for the treatment of colorectal carcinoma?
Which adverse effect is commonly associated with etoposide as an anticancer drug?
Which adverse effect is commonly associated with etoposide as an anticancer drug?
What is the primary mode of action of topoisomerase II inhibitors like irinotecan and topotecan?
What is the primary mode of action of topoisomerase II inhibitors like irinotecan and topotecan?
Which type of cancer is etoposide commonly used to treat?
Which type of cancer is etoposide commonly used to treat?
Etoposide primarily blocks cells in the late S to G 2 phase of the cell cycle.
Etoposide primarily blocks cells in the late S to G 2 phase of the cell cycle.
The adverse effects of topotecan include myelosuppression and diarrhea.
The adverse effects of topotecan include myelosuppression and diarrhea.
The primary route of administration for etoposide is intravenous (IV) or oral.
The primary route of administration for etoposide is intravenous (IV) or oral.
Which type of tumors sensitive to steroid hormones may be both hormone responsive and hormone dependent?
Which type of tumors sensitive to steroid hormones may be both hormone responsive and hormone dependent?
Which agent is used for the treatment of hormone dependent tumors by targeting intracellular receptors?
Which agent is used for the treatment of hormone dependent tumors by targeting intracellular receptors?
What type of drugs are used for the treatment of hormone dependent tumors that are sensitive to steroid hormones?
What type of drugs are used for the treatment of hormone dependent tumors that are sensitive to steroid hormones?
What is the primary mode of action of tamoxifen?
What is the primary mode of action of tamoxifen?
In which type of cancer is tamoxifen considered as first-line therapy?
In which type of cancer is tamoxifen considered as first-line therapy?
What is the dual role of tamoxifen in bone and endometrium, respectively?
What is the dual role of tamoxifen in bone and endometrium, respectively?
What is the primary mode of action of tamoxifen?
What is the primary mode of action of tamoxifen?
What is the primary route of metabolism for taxane family drugs like docetaxel and paclitaxel?
What is the primary route of metabolism for taxane family drugs like docetaxel and paclitaxel?
Which adverse effect is specifically associated with Doxorubicin?
Which adverse effect is specifically associated with Doxorubicin?
How is hemorrhagic cystitis, a common adverse effect of Cyclophosphamide, minimized?
How is hemorrhagic cystitis, a common adverse effect of Cyclophosphamide, minimized?
Tamoxifen is an estrogen antagonist in breast tissue and an agonist in bone and endometrium.
Tamoxifen is an estrogen antagonist in breast tissue and an agonist in bone and endometrium.
Tamoxifen is primarily metabolized in the kidneys.
Tamoxifen is primarily metabolized in the kidneys.
Tamoxifen can cause adverse effects such as hot flashes, skin rashes, and thromboembolism.
Tamoxifen can cause adverse effects such as hot flashes, skin rashes, and thromboembolism.
Tamoxifen is primarily used for the treatment of metastatic testicular carcinoma and systemic Hodgkin and non-Hodgkin lymphomas.
Tamoxifen is primarily used for the treatment of metastatic testicular carcinoma and systemic Hodgkin and non-Hodgkin lymphomas.
Which type of cancer is the primary target for aromatase inhibitors like anastrozole and letrozole?
Which type of cancer is the primary target for aromatase inhibitors like anastrozole and letrozole?
How are aromatase inhibitors like anastrozole and letrozole primarily eliminated from the body?
How are aromatase inhibitors like anastrozole and letrozole primarily eliminated from the body?
Which of the following is NOT a predisposition associated with the use of aromatase inhibitors like anastrozole and letrozole?
Which of the following is NOT a predisposition associated with the use of aromatase inhibitors like anastrozole and letrozole?
Aromatase inhibitors decrease the production of estrogen in premenopausal women.
Aromatase inhibitors decrease the production of estrogen in premenopausal women.
Aromatase inhibitors are primarily eliminated through feces.
Aromatase inhibitors are primarily eliminated through feces.
Aromatase inhibitors are the first-line therapy for breast cancer in postmenopausal women.
Aromatase inhibitors are the first-line therapy for breast cancer in postmenopausal women.
Which adverse effects are specifically associated with antiandrogens used in the treatment of prostate cancer?
Which adverse effects are specifically associated with antiandrogens used in the treatment of prostate cancer?
What is the primary route of administration for GnRH analogs used in the treatment of prostatic cancer?
What is the primary route of administration for GnRH analogs used in the treatment of prostatic cancer?
Which adverse effects are specifically associated with anticancer drugs like GnRH analogs?
Which adverse effects are specifically associated with anticancer drugs like GnRH analogs?
GnRH analogs like leuprolide, goserelin, and triptorelin are primarily used for the treatment of breast cancer.
GnRH analogs like leuprolide, goserelin, and triptorelin are primarily used for the treatment of breast cancer.
Antiandrogens like flutamide, nilutamide, and bicalutamide compete with natural hormones to bind on the androgen receptor.
Antiandrogens like flutamide, nilutamide, and bicalutamide compete with natural hormones to bind on the androgen receptor.
The primary adverse effect of antiandrogens is constipation.
The primary adverse effect of antiandrogens is constipation.
Antibodies such as bevacizumab and cetuximab bind to receptors or ligands in tumor cells. (True/False)
Antibodies such as bevacizumab and cetuximab bind to receptors or ligands in tumor cells. (True/False)
Tyrosine kinase inhibitors inhibit ligand activity in receptors. (True/False)
Tyrosine kinase inhibitors inhibit ligand activity in receptors. (True/False)
Resistance and relapse can be minimized by long-term, continuous therapy and single drug treatment. (True/False)
Resistance and relapse can be minimized by long-term, continuous therapy and single drug treatment. (True/False)
What is the primary mode of action of tyrosine kinase inhibitors used in targeted therapy for cancer?
What is the primary mode of action of tyrosine kinase inhibitors used in targeted therapy for cancer?
Which type of cancer is commonly treated with antibodies like bevacizumab and cetuximab as part of targeted therapy?
Which type of cancer is commonly treated with antibodies like bevacizumab and cetuximab as part of targeted therapy?
What is the primary route of excretion for antibodies used in targeted therapy for cancer?
What is the primary route of excretion for antibodies used in targeted therapy for cancer?
Flashcards
What are the goals of cancer treatment?
What are the goals of cancer treatment?
Control and prevention of disease relapse.
How to minimize resistance and relapse in cancer treatment?
How to minimize resistance and relapse in cancer treatment?
Combination therapy with intermittent scheduling is recommended to minimize resistance and relapse in cancer treatment.
How is anticancer drug dosage determined?
How is anticancer drug dosage determined?
Anticancer drug dosages are determined based on the patient's body surface area.
What are common toxicities of anticancer drugs?
What are common toxicities of anticancer drugs?
Signup and view all the flashcards
Is combination therapy less successful in cancer treatment?
Is combination therapy less successful in cancer treatment?
Signup and view all the flashcards
Do the goals of cancer treatment include cure and control of disease?
Do the goals of cancer treatment include cure and control of disease?
Signup and view all the flashcards
Can short term, intensive, intermittent therapy and combination minimize resistance and relapse?
Can short term, intensive, intermittent therapy and combination minimize resistance and relapse?
Signup and view all the flashcards
Do anticancer drugs only cause minor side effects?
Do anticancer drugs only cause minor side effects?
Signup and view all the flashcards
Which phase of the cell cycle do antimetabolites target?
Which phase of the cell cycle do antimetabolites target?
Signup and view all the flashcards
What's the primary mode of action of antimetabolites?
What's the primary mode of action of antimetabolites?
Signup and view all the flashcards
Give an example of an antimetabolite drug.
Give an example of an antimetabolite drug.
Signup and view all the flashcards
How does Methotrexate (MTX) work as an anticancer drug?
How does Methotrexate (MTX) work as an anticancer drug?
Signup and view all the flashcards
How is Methotrexate (MTX) administered?
How is Methotrexate (MTX) administered?
Signup and view all the flashcards
How to minimize renal toxicity caused by Methotrexate?
How to minimize renal toxicity caused by Methotrexate?
Signup and view all the flashcards
What are common adverse effects of Methotrexate?
What are common adverse effects of Methotrexate?
Signup and view all the flashcards
Is Methotrexate antimetabolite that affects folic acid?
Is Methotrexate antimetabolite that affects folic acid?
Signup and view all the flashcards
Does Methotrexate inhibit de novo purine nucleotide synthesis?
Does Methotrexate inhibit de novo purine nucleotide synthesis?
Signup and view all the flashcards
Is Methotrexate primarily excreted via feces?
Is Methotrexate primarily excreted via feces?
Signup and view all the flashcards
Can Methotrexate cause mucositis and myelosuppression?
Can Methotrexate cause mucositis and myelosuppression?
Signup and view all the flashcards
What's the primary mode of action of 5-Fluorouracil (5-FU)?
What's the primary mode of action of 5-Fluorouracil (5-FU)?
Signup and view all the flashcards
Which type of cancer is 5-Fluorouracil (5-FU) commonly used for?
Which type of cancer is 5-Fluorouracil (5-FU) commonly used for?
Signup and view all the flashcards
How does 5-Fluorouracil (5-FU) cause thymineless death?
How does 5-Fluorouracil (5-FU) cause thymineless death?
Signup and view all the flashcards
Does 5-Fluorouracil (5-FU) inhibition of Thymidylate Synthase lead to thymineless death?
Does 5-Fluorouracil (5-FU) inhibition of Thymidylate Synthase lead to thymineless death?
Signup and view all the flashcards
Is 5-Fluorouracil (5-FU) commonly used in the treatment of pancreatic cancer?
Is 5-Fluorouracil (5-FU) commonly used in the treatment of pancreatic cancer?
Signup and view all the flashcards
Is the primary mode of action of antimetabolites inhibiting DNA synthesis?
Is the primary mode of action of antimetabolites inhibiting DNA synthesis?
Signup and view all the flashcards
How does elevated dihdropyrimidine dehydrogenase (DPD) activity impact 5-Fluorouracil (5-FU)?
How does elevated dihdropyrimidine dehydrogenase (DPD) activity impact 5-Fluorouracil (5-FU)?
Signup and view all the flashcards
Which adverse effect is common with 5-Fluorouracil (5-FU)?
Which adverse effect is common with 5-Fluorouracil (5-FU)?
Signup and view all the flashcards
What is the primary mode of action of doxorubicin?
What is the primary mode of action of doxorubicin?
Signup and view all the flashcards
How is doxorubicin primarily administered?
How is doxorubicin primarily administered?
Signup and view all the flashcards
What is the mechanism of action of bleomycin?
What is the mechanism of action of bleomycin?
Signup and view all the flashcards
Which type of cancer is doxorubicin commonly used to treat?
Which type of cancer is doxorubicin commonly used to treat?
Signup and view all the flashcards
Does doxorubicin bind to DNA and induce breaks?
Does doxorubicin bind to DNA and induce breaks?
Signup and view all the flashcards
Is bleomycin cell cycle specific?
Is bleomycin cell cycle specific?
Signup and view all the flashcards
Does bleomycin inhibit topoisomerases?
Does bleomycin inhibit topoisomerases?
Signup and view all the flashcards
Is doxorubicin primarily administered orally?
Is doxorubicin primarily administered orally?
Signup and view all the flashcards
What is the primary route of excretion for doxorubicin?
What is the primary route of excretion for doxorubicin?
Signup and view all the flashcards
Which adverse effect is specifically associated with doxorubicin?
Which adverse effect is specifically associated with doxorubicin?
Signup and view all the flashcards
How is doxorubicin primarily metabolized?
How is doxorubicin primarily metabolized?
Signup and view all the flashcards
What is the primary route of excretion for bleomycin?
What is the primary route of excretion for bleomycin?
Signup and view all the flashcards
What is a common adverse effect associated with bleomycin?
What is a common adverse effect associated with bleomycin?
Signup and view all the flashcards
What is the primary mode of action of bleomycin?
What is the primary mode of action of bleomycin?
Signup and view all the flashcards
Is bleomycin primarily excreted via feces?
Is bleomycin primarily excreted via feces?
Signup and view all the flashcards
Can bleomycin cause pulmonary fibrosis?
Can bleomycin cause pulmonary fibrosis?
Signup and view all the flashcards
Does bleomycin inhibit topoisomerases?
Does bleomycin inhibit topoisomerases?
Signup and view all the flashcards
What is the primary mode of action of alkylating agents?
What is the primary mode of action of alkylating agents?
Signup and view all the flashcards
Do alkylating agents affect resting or cycling cells?
Do alkylating agents affect resting or cycling cells?
Signup and view all the flashcards
What common adverse effect is associated with alkylating agents?
What common adverse effect is associated with alkylating agents?
Signup and view all the flashcards
Do alkylating agents primarily affect resting cells?
Do alkylating agents primarily affect resting cells?
Signup and view all the flashcards
Is bleomycin primarily excreted via feces?
Is bleomycin primarily excreted via feces?
Signup and view all the flashcards
