Antibodies, Antigens, and Generation of Diversity
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Questions and Answers

Which DNA segments undergo rearrangement to form a DNA sequence encoding the V region of antibodies?

  • D segments (correct)
  • Functional C genes
  • V and J segments
  • C region genes
  • How many functional C region genes are there in the H-chain gene group?

  • 6
  • 3
  • 9 (correct)
  • 12
  • In a B cell, what is transcribed, spliced, and translated into a H-chain protein?

  • D segments
  • V region genes
  • J segments
  • Rearranged gene from VDJ segments (correct)
  • Where are the functional V segment genes located for H-chain genes in the germ line?

    <p>In the H-chain gene loci</p> Signup and view all the answers

    Which segment recombines with one of many D segments and several J segments to produce a functional VDJ gene in a developing B cell?

    <p>V segments</p> Signup and view all the answers

    What is the main purpose of different antibody classes with different biological activities?

    <p>To deal with antigens with different properties entering the body at different sites</p> Signup and view all the answers

    Which chromosomes are antibody genes located on?

    <p>Three separate chromosomes</p> Signup and view all the answers

    In mature B cells or plasma cells, how does the DNA encoding the variable region of the H-chain exist?

    <p>As a continuous sequence</p> Signup and view all the answers

    What do V, D, and J segments encode in antibody genes?

    <p>Amino acids</p> Signup and view all the answers

    What structural features make up the V region for H-chains?

    <p>V, D, and J segments</p> Signup and view all the answers

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