Antibodies, Antigens, and Generation of Diversity
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Questions and Answers

Which DNA segments undergo rearrangement to form a DNA sequence encoding the V region of antibodies?

  • D segments (correct)
  • Functional C genes
  • V and J segments
  • C region genes

How many functional C region genes are there in the H-chain gene group?

  • 6
  • 3
  • 9 (correct)
  • 12

In a B cell, what is transcribed, spliced, and translated into a H-chain protein?

  • D segments
  • V region genes
  • J segments
  • Rearranged gene from VDJ segments (correct)

Where are the functional V segment genes located for H-chain genes in the germ line?

<p>In the H-chain gene loci (A)</p> Signup and view all the answers

Which segment recombines with one of many D segments and several J segments to produce a functional VDJ gene in a developing B cell?

<p>V segments (C)</p> Signup and view all the answers

What is the main purpose of different antibody classes with different biological activities?

<p>To deal with antigens with different properties entering the body at different sites (C)</p> Signup and view all the answers

Which chromosomes are antibody genes located on?

<p>Three separate chromosomes (A)</p> Signup and view all the answers

In mature B cells or plasma cells, how does the DNA encoding the variable region of the H-chain exist?

<p>As a continuous sequence (A)</p> Signup and view all the answers

What do V, D, and J segments encode in antibody genes?

<p>Amino acids (D)</p> Signup and view all the answers

What structural features make up the V region for H-chains?

<p>V, D, and J segments (D)</p> Signup and view all the answers

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