Antibodies, Antigens, and Generation of Diversity

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10 Questions

Which DNA segments undergo rearrangement to form a DNA sequence encoding the V region of antibodies?

D segments

How many functional C region genes are there in the H-chain gene group?

9

In a B cell, what is transcribed, spliced, and translated into a H-chain protein?

Rearranged gene from VDJ segments

Where are the functional V segment genes located for H-chain genes in the germ line?

In the H-chain gene loci

Which segment recombines with one of many D segments and several J segments to produce a functional VDJ gene in a developing B cell?

V segments

What is the main purpose of different antibody classes with different biological activities?

To deal with antigens with different properties entering the body at different sites

Which chromosomes are antibody genes located on?

Three separate chromosomes

In mature B cells or plasma cells, how does the DNA encoding the variable region of the H-chain exist?

As a continuous sequence

What do V, D, and J segments encode in antibody genes?

Amino acids

What structural features make up the V region for H-chains?

V, D, and J segments

Explore the functional diversity and antigen receptor diversity of antibodies, as well as the process of generating different antibody classes with unique biological activities to combat various antigens. Learn about the structural features of antibody variable regions in this informative quiz.

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