Podcast
Questions and Answers
Why is tetracycline effective in treating periodontal disease?
Why is tetracycline effective in treating periodontal disease?
What is a benefit of doxycycline compared to other antibiotics?
What is a benefit of doxycycline compared to other antibiotics?
What is the typical duration of antibiotic treatment for periodontal disease?
What is the typical duration of antibiotic treatment for periodontal disease?
Why is it important to avoid alcohol consumption with metronidazole?
Why is it important to avoid alcohol consumption with metronidazole?
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When is local delivery antibiotics typically used?
When is local delivery antibiotics typically used?
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What is the name of the locally delivered antibiotic that contains doxycycline?
What is the name of the locally delivered antibiotic that contains doxycycline?
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What is the goal of host modulation therapy?
What is the goal of host modulation therapy?
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When should host modulation therapy be used?
When should host modulation therapy be used?
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What is the key factor in the effectiveness of antibiotic treatment for periodontal disease?
What is the key factor in the effectiveness of antibiotic treatment for periodontal disease?
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Why is mechanical cleaning important in addition to antibiotic treatment?
Why is mechanical cleaning important in addition to antibiotic treatment?
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What is the primary goal of antibiotics in the treatment of periodontal disease?
What is the primary goal of antibiotics in the treatment of periodontal disease?
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When should antibiotics be used in the treatment of periodontal disease?
When should antibiotics be used in the treatment of periodontal disease?
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What type of periodontitis is most often treated with antibiotics?
What type of periodontitis is most often treated with antibiotics?
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What is refractory periodontitis?
What is refractory periodontitis?
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Why should bactericidal and bacteriostatic drugs not be given at the same time?
Why should bactericidal and bacteriostatic drugs not be given at the same time?
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What is the role of antibiotics in phase one of periodontal treatment?
What is the role of antibiotics in phase one of periodontal treatment?
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What is the primary mechanism of action of bactericidal drugs?
What is the primary mechanism of action of bactericidal drugs?
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What is the link between aggressive periodontitis and a specific type of bacteria?
What is the link between aggressive periodontitis and a specific type of bacteria?
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What is the primary mechanism of NSAIDs in host modulation therapy?
What is the primary mechanism of NSAIDs in host modulation therapy?
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What is the primary mechanism of bisphosphonates in host modulation therapy?
What is the primary mechanism of bisphosphonates in host modulation therapy?
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What is the FDA-approved medication for host modulation therapy?
What is the FDA-approved medication for host modulation therapy?
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What does subantimicrobial dose doxycycline inhibit?
What does subantimicrobial dose doxycycline inhibit?
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What is the typical dosage for subantimicrobial dose doxycycline?
What is the typical dosage for subantimicrobial dose doxycycline?
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What is the purpose of occlusal correction in periodontal treatment?
What is the purpose of occlusal correction in periodontal treatment?
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What is traumatic occlusion?
What is traumatic occlusion?
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What is fremitus?
What is fremitus?
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What is the primary mechanism of EMD in periodontal treatment?
What is the primary mechanism of EMD in periodontal treatment?
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What is the primary purpose of local host modulation therapy?
What is the primary purpose of local host modulation therapy?
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What is the primary goal of occlusal therapy in Phase One?
What is the primary goal of occlusal therapy in Phase One?
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What is the purpose of a bite guard or occlusal guard?
What is the purpose of a bite guard or occlusal guard?
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When is occlusal adjustment or corona plasti usually done?
When is occlusal adjustment or corona plasti usually done?
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What is unit splinting used for according to the board exam?
What is unit splinting used for according to the board exam?
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What is the main purpose of furcation correction?
What is the main purpose of furcation correction?
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What is furcation plasti?
What is furcation plasti?
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What is the purpose of tunneling in furcation correction?
What is the purpose of tunneling in furcation correction?
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What is root amputation?
What is root amputation?
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What is the result of hemisection?
What is the result of hemisection?
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Why is the distal buccal root of a maxillary first molar often chosen for root amputation?
Why is the distal buccal root of a maxillary first molar often chosen for root amputation?
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Study Notes
Antibiotics in Periodontal Disease
- Antibiotics aim to decrease the number of bacteria in the periodontal pocket, which makes sense because bacteria in plaque are the initiating factor in periodontal disease.
- Antibiotics should only be used as an adjunct to mechanical debridement during phase one, which includes non-surgical options like plaque control, patient education, scaling, and root planing.
- Antibiotics are most often employed in the aggressive form of periodontitis, and also in cases of refractory periodontitis that do not resolve despite proper treatment.
- Remember, "A" for aggressive, and "A" for antibiotics.
Types of Antibiotics
- Bactericidal and bacteriostatic drugs should not be given at the same time; bactericidal drugs kill bacteria, while bacteriostatic drugs stop their growth.
- Tetracycline concentrates in the gingival crevicular fluid, making it effective in targeting plaque bacteria.
- Doxycycline, a type of tetracycline, is often prescribed and only requires one dose per day, which may improve patient compliance.
- The most common and effective antibiotic regimen for periodontal disease is a combination of amoxicillin and metronidazole, taken for 14 days.
Local Delivery Antibiotics
- Local delivery antibiotics are used to target specific pockets that are not resolving, and are delivered directly into the affected area.
- The specific guidelines for local delivery antibiotics (LDA) use are:
- Localized recurrent or residual pockets that are not going away
- Probing depths greater than or equal to 5 millimeters with inflammation
- There are three commonly used locally delivered antibiotics: Arestin, Atridox, and PerioChip.
- Remember, Arestin corresponds to minocycline, Atridox corresponds to doxycycline, and PerioChip corresponds to chlorhexidine.
Host Modulation Therapy
- Host modulation therapy aims to down-regulate the destructive aspects of the host response to bacteria.
- It is used as an adjunct to mechanical debridement, and should only be used in cases of chronic periodontitis.
- There are three types of medicaments used in host modulation therapy: nonsteroidal anti-inflammatory drugs (NSAIDs), bisphosphonates, and sub-antimicrobial dose doxycycline.
- Sub-antimicrobial dose doxycycline is the only FDA-approved and ADEA-accepted medication for host modulation therapy.
Local Host Modulation Therapy
- Local host modulation therapy involves administering host-modifying agents directly into the affected area.
- Examples of local host modulation therapy include enamel matrix proteins (EMD) and platelet-derived growth factor (PDGF).
Occlusal Correction
- Occlusal correction is used to address traumatic occlusion, which can accelerate periodontal disease.
- Articulating paper or occlusal indicating wax can be used to diagnose traumatic occlusion.
- There are two types of traumatic occlusion: primary and secondary.
- Primary traumatic occlusion is caused by excessive forces on a normal periodontium, while secondary traumatic occlusion is caused by normal occlusal forces on a reduced periodontium.
- Fremitus is a vibration of teeth upon closing, and can be used to diagnose traumatic occlusion.
Treatment Options for Occlusal Correction
- Treatment options for occlusal correction include occlusal adjustment, coronal plasty, and an occlusal appliance (also known as a bite guard).
- Unit splinting is used to improve patient comfort and function, but is not indicated for fremitus unless it bothers the patient.
Furcation Correction
- Furcation correction is used to address furcation involvement, which can make it difficult to keep the area clean.
- There are four treatment options for furcation correction:
- Furcation plasty: to open up the furcation area and smooth it out for better access.
- Tunneling: to remove bone and move the tissues apically to create a Gleckman Class IV, which allows for easier cleaning.
- Root amputation or resection: to cut off one of the roots to facilitate cleaning.
- Hemisection: to cut the tooth in half and retain it as two separate teeth.
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Description
Learn about the role of antibiotics in treating periodontal disease, including their effect on bacteria and plaque. Understand how they should be used in conjunction with mechanical debridement.