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Antibiotics and Mechanism of Action
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Antibiotics and Mechanism of Action

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Questions and Answers

What is a crucial criterion for an effective antibiotic?

  • It must be able to affect microbial physiology that does not exist or is greatly modified in humans (correct)
  • It must be able to affect human physiology
  • It must be able to affect only gram-positive bacteria
  • It must be able to affect only gram-negative bacteria
  • What is the primary mechanism of action of bacteriostatic antibiotics?

  • They prevent the growth of organisms (correct)
  • They stimulate the immune system
  • They kill the target organisms
  • They inhibit protein synthesis
  • What is the term for the compound produced by one microbe that adversely affects other microbes?

  • Antiviral
  • Antibiotic (correct)
  • Bactericidal
  • Antimicrobial
  • Who is credited with discovering the first antibiotic, prontosil?

    <p>Gerhard Domagk</p> Signup and view all the answers

    What is the purpose of the Kirby-Bauer Disk Susceptibility test?

    <p>To test the sensitivity of an organism to multiple antibiotics</p> Signup and view all the answers

    What is the target of beta-lactam antibiotics, such as penicillin and cephalosporins?

    <p>The bacterial peptidoglycan cell wall</p> Signup and view all the answers

    What is the mechanism of action of quinolones, such as nalidixic acid and ciprofloxacin?

    <p>They block bacterial DNA gyrase</p> Signup and view all the answers

    What is the mechanism of action of sulfa drugs?

    <p>They block the action of folic acid</p> Signup and view all the answers

    What is the term for the lowest concentration of an antibiotic that prevents the growth of an organism?

    <p>MIC (minimal inhibitory concentration)</p> Signup and view all the answers

    Who is credited with proposing that bacteria and molds engage in perpetual battle for survival?

    <p>Ernest Duchesne</p> Signup and view all the answers

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