Anti-Muscarinic and Anti-Serotonin Drugs Quiz
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Questions and Answers

Which category of drugs increases upper GIT motility and gastric emptying?

  • Laxatives
  • Antispasmodic drugs
  • Prokinetic drugs (correct)
  • Antidiarrheal drugs

What is the mechanism of action of Macrolide antibiotics (Erythromycin) in increasing gastric motility?

  • Stimulating dopamine receptors
  • Antagonizing cholinergic receptors
  • Blocking serotonin receptors
  • Stimulating motilin receptors (correct)

Which drug is used for treating conditions like Gastroesophageal reflux (GERD) and Gastroparesis?

  • Mosapride
  • Bethanechol
  • Domperidone
  • Metoclopramide (correct)

What is the main cause of vomiting according to the text?

<p>Stress-induced dopamine release (B)</p> Signup and view all the answers

Which class of drugs is responsible for acting on the chemoreceptor trigger zone (CTZ) to prevent vomiting?

<p>Antiemetic agents (C)</p> Signup and view all the answers

Which drug category is used for decreasing GIT motility?

<p>Antispasmodic drugs (A)</p> Signup and view all the answers

What is the main effect of blocking dopamine receptors in the chemoreceptor trigger zone of the medulla?

<p>Prokinetic action (D)</p> Signup and view all the answers

Which adverse effect is commonly associated with anti-dopamine drugs?

<p>Sedation (C)</p> Signup and view all the answers

What distinguishes Domperidone from Metoclopramide in terms of extrapyramidal effects?

<p>Domperidone has no extrapyramidal effects (B)</p> Signup and view all the answers

Which drug is more likely to induce hyperprolactinemia due to D2 blockade in the pituitary gland?

<p>Metoclopramide (D)</p> Signup and view all the answers

Which anti-dopamine drug does not pass the blood-brain barrier (BBB)?

<p>Domperidone (D)</p> Signup and view all the answers

What is a significant adverse effect of Metoclopramide that is not associated with Domperidone?

<p>Extrapyramidal effects (A)</p> Signup and view all the answers

What is the mechanism of action of osmotic laxatives?

<p>Increase osmotic pressure to draw water into the intestinal lumen (C)</p> Signup and view all the answers

When should stimulant laxatives be used according to the text?

<p>Short-term treatment of constipation (D)</p> Signup and view all the answers

Which condition can overuse of osmotic laxatives lead to?

<p>Metabolic alkalosis (C)</p> Signup and view all the answers

What is the main side effect associated with stimulant laxatives?

<p>Diarrhea and dehydration (A)</p> Signup and view all the answers

What is the role of fecal softeners according to the text?

<p>To soften stool for easier passage through the intestinal tract (C)</p> Signup and view all the answers

What is the main indication for using osmotic laxatives as mentioned in the text?

<p>To treat opioid-induced constipation (D)</p> Signup and view all the answers

What is the mechanism of action of anti-muscarinic drugs like hyoscine (scopolamine)?

<p>They compete with acetylcholine at muscarinic receptors in the gut and CNS (C)</p> Signup and view all the answers

What is the main indication for using anti-histaminic drugs like diphenhydramine?

<p>Relief of allergic rhinitis and allergic reactions (D)</p> Signup and view all the answers

What is the mechanism of action of anti-serotonin drugs like ondansetron?

<p>Blocking 5-HT3 receptors in the GIT and CTZ center (D)</p> Signup and view all the answers

What are the side effects commonly associated with anti-serotonin drugs?

<p>Drowsiness and constipation (B)</p> Signup and view all the answers

Which type of drugs are used to treat motion sickness, vestibulocochlear disease, and hyperemesis gravidarum?

<p>Anti-histaminic drugs (B)</p> Signup and view all the answers

What is the role of prokinetics (motility stimulants) like domperidone in managing constipation?

<p>Stimulating motility in the gut by blocking dopamine D2 receptors (D)</p> Signup and view all the answers

What is the first priority in the treatment of acute diarrhea?

<p>Maintenance of fluid and electrolyte balance (C)</p> Signup and view all the answers

Which drug class acts on opioid receptors in the intestine to decrease peristalsis?

<p>Antimotility agents (C)</p> Signup and view all the answers

In which cases should opiate-like antimotility drugs be avoided?

<p>Active inflammatory bowel disease (B)</p> Signup and view all the answers

What is the mechanism of action of drugs that increase the viscosity of gut contents?

<p>Adsorb water and irritant substances (D)</p> Signup and view all the answers

Which class of drugs are used to treat nausea and vomiting?

<p>Antiemetic drugs (D)</p> Signup and view all the answers

What are the 4 common classes of antiemetic drugs mentioned in the text?

<p>D2 receptor blockers, M receptor blockers, 5-HT3 receptor blockers, H1-receptor blockers (C)</p> Signup and view all the answers

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