Anti-Muscarinic and Anti-Serotonin Drugs Quiz
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Questions and Answers

Which category of drugs increases upper GIT motility and gastric emptying?

  • Laxatives
  • Antispasmodic drugs
  • Prokinetic drugs (correct)
  • Antidiarrheal drugs
  • What is the mechanism of action of Macrolide antibiotics (Erythromycin) in increasing gastric motility?

  • Stimulating dopamine receptors
  • Antagonizing cholinergic receptors
  • Blocking serotonin receptors
  • Stimulating motilin receptors (correct)
  • Which drug is used for treating conditions like Gastroesophageal reflux (GERD) and Gastroparesis?

  • Mosapride
  • Bethanechol
  • Domperidone
  • Metoclopramide (correct)
  • What is the main cause of vomiting according to the text?

    <p>Stress-induced dopamine release</p> Signup and view all the answers

    Which class of drugs is responsible for acting on the chemoreceptor trigger zone (CTZ) to prevent vomiting?

    <p>Antiemetic agents</p> Signup and view all the answers

    Which drug category is used for decreasing GIT motility?

    <p>Antispasmodic drugs</p> Signup and view all the answers

    What is the main effect of blocking dopamine receptors in the chemoreceptor trigger zone of the medulla?

    <p>Prokinetic action</p> Signup and view all the answers

    Which adverse effect is commonly associated with anti-dopamine drugs?

    <p>Sedation</p> Signup and view all the answers

    What distinguishes Domperidone from Metoclopramide in terms of extrapyramidal effects?

    <p>Domperidone has no extrapyramidal effects</p> Signup and view all the answers

    Which drug is more likely to induce hyperprolactinemia due to D2 blockade in the pituitary gland?

    <p>Metoclopramide</p> Signup and view all the answers

    Which anti-dopamine drug does not pass the blood-brain barrier (BBB)?

    <p>Domperidone</p> Signup and view all the answers

    What is a significant adverse effect of Metoclopramide that is not associated with Domperidone?

    <p>Extrapyramidal effects</p> Signup and view all the answers

    What is the mechanism of action of osmotic laxatives?

    <p>Increase osmotic pressure to draw water into the intestinal lumen</p> Signup and view all the answers

    When should stimulant laxatives be used according to the text?

    <p>Short-term treatment of constipation</p> Signup and view all the answers

    Which condition can overuse of osmotic laxatives lead to?

    <p>Metabolic alkalosis</p> Signup and view all the answers

    What is the main side effect associated with stimulant laxatives?

    <p>Diarrhea and dehydration</p> Signup and view all the answers

    What is the role of fecal softeners according to the text?

    <p>To soften stool for easier passage through the intestinal tract</p> Signup and view all the answers

    What is the main indication for using osmotic laxatives as mentioned in the text?

    <p>To treat opioid-induced constipation</p> Signup and view all the answers

    What is the mechanism of action of anti-muscarinic drugs like hyoscine (scopolamine)?

    <p>They compete with acetylcholine at muscarinic receptors in the gut and CNS</p> Signup and view all the answers

    What is the main indication for using anti-histaminic drugs like diphenhydramine?

    <p>Relief of allergic rhinitis and allergic reactions</p> Signup and view all the answers

    What is the mechanism of action of anti-serotonin drugs like ondansetron?

    <p>Blocking 5-HT3 receptors in the GIT and CTZ center</p> Signup and view all the answers

    What are the side effects commonly associated with anti-serotonin drugs?

    <p>Drowsiness and constipation</p> Signup and view all the answers

    Which type of drugs are used to treat motion sickness, vestibulocochlear disease, and hyperemesis gravidarum?

    <p>Anti-histaminic drugs</p> Signup and view all the answers

    What is the role of prokinetics (motility stimulants) like domperidone in managing constipation?

    <p>Stimulating motility in the gut by blocking dopamine D2 receptors</p> Signup and view all the answers

    What is the first priority in the treatment of acute diarrhea?

    <p>Maintenance of fluid and electrolyte balance</p> Signup and view all the answers

    Which drug class acts on opioid receptors in the intestine to decrease peristalsis?

    <p>Antimotility agents</p> Signup and view all the answers

    In which cases should opiate-like antimotility drugs be avoided?

    <p>Active inflammatory bowel disease</p> Signup and view all the answers

    What is the mechanism of action of drugs that increase the viscosity of gut contents?

    <p>Adsorb water and irritant substances</p> Signup and view all the answers

    Which class of drugs are used to treat nausea and vomiting?

    <p>Antiemetic drugs</p> Signup and view all the answers

    What are the 4 common classes of antiemetic drugs mentioned in the text?

    <p>D2 receptor blockers, M receptor blockers, 5-HT3 receptor blockers, H1-receptor blockers</p> Signup and view all the answers

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