Pharmacology of Antimuscarinic Drugs

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Questions and Answers

What is the primary use of atropine in routine preoperative medications?

  • To decrease airway secretions
  • To relieve anxiety
  • To increase airway secretions (correct)
  • To induce anesthesia

In the case of marked vagal stimulation, what is the appropriate therapy to improve cardiac output?

  • Beta-agonists
  • Calcium channel blockers
  • Parenteral atropine or similar antimuscarinic drug (correct)
  • Diuretics

For which condition are antimuscarinic agents rarely used?

  • Peptic ulcer disease (correct)
  • Abdominal colic
  • Traveler's diarrhea
  • Mild hypermotility conditions

Which drug is selective for M3 receptors and used to relieve bladder spasms?

<p>Oxybutynin (D)</p> Signup and view all the answers

What condition can be alleviated by antimuscarinic agents?

<p>Hyperhidrosis (D)</p> Signup and view all the answers

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Study Notes

Respiratory Disorders

  • Atropine increases airway secretions
  • Ipratropium is a synthetic version of atropine used to treat asthma

Cardiovascular Disorders

  • Vagal stimulation can reduce heart function
  • Atropine and similar drugs are given to counter this

Gastrointestinal Disorders

  • Antimuscarinic agents can ease stomach cramps, traveler's diarrhea, and other hypermotility situations
  • Often used with opioid antidiarrheal drugs
  • Not commonly used for peptic ulcers

Urinary Disorders

  • Atropine and similar drugs help urinary urgency in minor bladder inflammation
  • Oxybutynin helps bladder spasms after surgery and increases bladder capacity and continence

Other Applications

  • Antimuscarinic drugs reduce excessive sweating (hyperhidrosis)

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