25 Questions
Receptors for all of the hypophysiotropic hormones are coupled to G-proteins.
False
TRH is a hypophysiotropic hormone.
True
VIP stands for Very Important Peptide.
False
G-proteins are involved in the regulation of hypophysiotropic hormones.
True
Hypothalamic regulation is unrelated to hormonal function.
False
CRH-binding protein is only found in the peripheral circulation.
False
CRH-binding protein activates CRH in the peripheral circulation.
False
CRH-binding protein is found in the cytoplasm of corticotropes in the anterior pituitary.
True
CRH-binding protein is only involved in receptor internalization.
False
CRH-binding protein is involved in the function of corticotropes.
True
The anterior pituitary secretes five hormones.
False
Adrenocorticotropic hormone is also known as corticotropin.
True
The anterior pituitary secretes only one hormone.
False
An increase in intracellular Ca2+ levels is triggered.
True
The anterior pituitary secretes seven hormones.
False
The circumventricular organs are located inside the blood–brain barrier.
False
The circumventricular organs are not permeable.
False
The circumventricular organs are responsible for hormonal regulation.
True
The blood–brain barrier is permeable.
False
There are no organs outside the blood–brain barrier.
False
In humans, the posterior pituitary gland secretes oxytocin and arginine vasopressin.
True
The posterior pituitary gland secretes only one hormone, oxytocin.
False
Arginine vasopressin is also known as AVP.
True
The posterior pituitary gland secretes insulin.
False
Oxytocin and arginine vasopressin are secreted by the anterior pituitary gland.
False
Study Notes
Anterior Pituitary Hormones
- The anterior pituitary secretes six hormones, including adrenocorticotropic hormone (corticotropin, ACTH) and TRH.
- Other hormones secreted by the anterior pituitary include VIP and several others.
Hypothalamic Regulation of Hormonal Function
- Receptors for most hypophysiotropic hormones are coupled to G-proteins.
- A CRH-binding protein in the peripheral circulation inactivates CRH.
- This protein is also found in the cytoplasm of corticotropes in the anterior pituitary, where it may play a role in receptor internalization.
Circumventricular Organs
- There are areas of high permeability outside the blood–brain barrier, known as circumventricular organs (see Chapter 33).
Posterior Pituitary Secretions
- In most mammals, the posterior pituitary gland secretes two hormones: arginine vasopressin (AVP) and oxytocin.
Test your knowledge of the six hormones secreted by the anterior pituitary gland, including adrenocorticotropic hormone and others.
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