Animal Systems II: Cardiovascular Physiology Quiz
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Questions and Answers

What percentage of the total grade does the final exam account for?

  • 85% (correct)
  • 5%
  • 100%
  • 10%
  • Which module focuses on the electrical activity of the heart?

  • Module 1
  • Module 4
  • Module 2 (correct)
  • Module 3
  • What is a major function of the cardiovascular system?

  • Producing hormones
  • Continuously distributing blood (correct)
  • Filtering toxins from the blood
  • Regulating body temperature
  • How many modules are included in the Animal Systems II: Cardiovascular Physiology course?

    <p>7 (C)</p> Signup and view all the answers

    What is the estimated probability of an American developing cardiovascular disease?

    <p>1 in 4 (B)</p> Signup and view all the answers

    Which of the following is NOT covered in the course modules?

    <p>Nervous System Integration (C)</p> Signup and view all the answers

    What proportion of the total grade do the Canvas-based quizzes contribute?

    <p>10% (C)</p> Signup and view all the answers

    Which statement about cardiovascular disease is true?

    <p>It affects a significant percentage of dogs by age 13. (A)</p> Signup and view all the answers

    What are the two divisions of the cardiovascular system?

    <p>Systemic and Pulmonary (B)</p> Signup and view all the answers

    What is the primary measure of cardiac performance?

    <p>Cardiac Output (B)</p> Signup and view all the answers

    Which component is part of the distribution system of the cardiovascular system?

    <p>Systemic Arteries (D)</p> Signup and view all the answers

    In terms of anatomical structure, how many pumps does the heart consist of?

    <p>Two (B)</p> Signup and view all the answers

    What is the capacity of blood pumped per minute in humans?

    <p>5 L/min (B)</p> Signup and view all the answers

    Which region of the cardiovascular system is responsible for the exchange of gases?

    <p>Capillaries (C)</p> Signup and view all the answers

    During ventricular systole, which part of the heart collects blood?

    <p>Atria (A)</p> Signup and view all the answers

    Which of the following best describes the flow of blood in the cardiovascular system?

    <p>Unidirectional (A)</p> Signup and view all the answers

    What primarily regulates cardiovascular resistance?

    <p>Diameter of the vessel (D)</p> Signup and view all the answers

    How much does blood flow change when the diameter of the vessel is halved?

    <p>Decreases by 16 times (A)</p> Signup and view all the answers

    What is the mathematical representation of Poiseuille's law for blood flow?

    <p>Q = (P1 - P2) / R (C)</p> Signup and view all the answers

    Which factor is NOT a primary determinant of blood flow?

    <p>Length of the vessel (A)</p> Signup and view all the answers

    What condition can lead to increased blood viscosity?

    <p>High hematocrit levels (D)</p> Signup and view all the answers

    Which ventricle is responsible for generating approximately five times greater pressure?

    <p>Left ventricle (A)</p> Signup and view all the answers

    What factor does NOT affect resistance to blood flow?

    <p>Temperature of the fluid (B)</p> Signup and view all the answers

    What is the primary role of arterioles in the vascular system?

    <p>Regulate blood pressure through vasoconstriction (A)</p> Signup and view all the answers

    Which statement about capillaries is accurate?

    <p>They facilitate the exchange of metabolic substrates. (A)</p> Signup and view all the answers

    What is the function of venules and veins in the cardiovascular system?

    <p>Serve as blood reservoirs (C)</p> Signup and view all the answers

    What is the primary function of the lymphatic system regarding capillary exchange?

    <p>Remove excess fluid and waste from tissues (B)</p> Signup and view all the answers

    What does Poiseuille's law relate to in the vascular system?

    <p>Flow and resistance (C)</p> Signup and view all the answers

    Which mechanism is intrinsic to cardiovascular regulation?

    <p>Frank-Starling Law of the heart (D)</p> Signup and view all the answers

    What prevents backflow from the ventricles into the atria during ventricular contraction?

    <p>Mitral and tricuspid valves (C)</p> Signup and view all the answers

    During which phase are the mitral and tricuspid valves closed?

    <p>Isovolumetric contraction (B), Systole (D)</p> Signup and view all the answers

    What is primarily responsible for the direction of valve opening and closing?

    <p>Pressure gradients (A)</p> Signup and view all the answers

    Which heart generates higher pressure due to greater resistance?

    <p>Left heart (D)</p> Signup and view all the answers

    Which valves prevent backflow of blood from the aorta and pulmonary trunk into the ventricles?

    <p>Aortic and pulmonic semilunar valves (B)</p> Signup and view all the answers

    What happens during isovolumetric contraction?

    <p>AV valves are closed and semilunar valves are closed (D)</p> Signup and view all the answers

    What do we call the movement of fluid down a pressure gradient?

    <p>Flow (C)</p> Signup and view all the answers

    Which factor contributes to resistance in the cardiovascular system?

    <p>Friction and deflection forces (B)</p> Signup and view all the answers

    What is a primary consequence of cardiac pathologies such as valve failure and myocardium dysfunction?

    <p>Improper removal of metabolic wastes (C)</p> Signup and view all the answers

    Which factor does NOT influence the flow (Q) in the cardiovascular system according to Poiseuille's law?

    <p>Diameter of the heart chambers (B)</p> Signup and view all the answers

    In a typical canine, which cardiovascular measure is defined as the volume of blood pumped per minute by the heart?

    <p>Cardiac output (B)</p> Signup and view all the answers

    What triggers the regulation of blood flow through hormonal mechanisms such as the RAAS?

    <p>Decreased blood volume (A)</p> Signup and view all the answers

    Which side of the heart is responsible for pumping blood with the greatest flow?

    <p>Left side (B)</p> Signup and view all the answers

    What is the typical average blood pressure reading for humans?

    <p>120/80 mmHg (B)</p> Signup and view all the answers

    What physiological condition can occur when blood vessels encounter atherosclerosis?

    <p>Reduced blood flow to organs (D)</p> Signup and view all the answers

    Which statement about blood flow and pressure is correct?

    <p>Flow is directly proportional to pressure gradient (A)</p> Signup and view all the answers

    Flashcards

    What is the main function of the cardiovascular system?

    The continuous transport of blood throughout the body to deliver nutrients and remove waste products. It involves the heart, blood vessels, and blood.

    What are the key components of the cardiovascular system?

    The cardiovascular system comprises the heart, blood vessels (arteries, veins, capillaries), and blood. These components work together to circulate blood and transport essential substances.

    Explain the relationship between pressure and flow in the cardiovascular system.

    Pressure is the force exerted by the blood against the walls of blood vessels, while flow refers to the volume of blood moving through a vessel per unit time. Higher pressure leads to greater blood flow.

    What are cardiovascular diseases and why are they a concern?

    Cardiovascular diseases affect the heart and blood vessels, leading to problems like heart attacks, strokes, and high blood pressure. They are a major health concern, affecting a significant portion of the population.

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    How prevalent are cardiovascular diseases in humans and animals?

    A significant number of individuals, both humans and animals, are affected by cardiovascular diseases. Many animals develop heart problems by a certain age.

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    Why is early detection of cardiovascular disease important?

    Many cardiovascular diseases can progress without noticeable symptoms until they become serious. This makes early detection and prevention crucial.

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    What is cardiovascular physiology?

    The study and understanding of the cardiovascular system. It involves examining the heart's structure and function, blood vessel characteristics, and blood properties.

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    What are the main topics covered in this Cardiovascular Physiology course?

    This course covers various aspects of the cardiovascular system, including its structure, function, electrical activity, and regulation.

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    What is Cardiac Output?

    The volume of blood pumped by the heart per minute.

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    What are the two main divisions of the Cardiovascular System?

    The cardiovascular system consists of two main divisions: systemic and pulmonary. They are responsible for transporting blood throughout the body, delivering oxygen and nutrients, and removing waste products.

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    What is the function of the Heart?

    The heart is a powerful pump that propels blood through the body. It is responsible for maintaining blood pressure and ensuring that oxygen and nutrients are delivered to the tissues. It is divided into two functionally independent pumps, each consisting of an atrium and a ventricle.

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    What is the role of the Arteries?

    The arteries are responsible for distributing blood from the heart to the rest of the body. They can adjust their outflow to meet the demands of the tissues.

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    What are Capillaries?

    Capillaries are tiny blood vessels where the exchange of oxygen, nutrients, and waste products occurs between the blood and the tissues.

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    What is the role of Veins?

    The veins collect blood from the tissues and return it to the heart. The atria function as collection chambers during ventricular systole (contraction).

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    What is the direction of blood flow in the Cardiovascular system?

    Blood flow in the cardiovascular system is unidirectional, meaning it flows in one direction only.

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    What causes blood to flow in the body?

    The pressure difference created by the heart's pumping action drives blood flow through the cardiovascular system.

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    How do heart valves ensure unidirectional blood flow?

    Valves in the heart prevent backflow of blood, ensuring unidirectional flow. Mitral and tricuspid valves (AV valves) stop backflow into the atria during ventricular contraction. Aortic and pulmonic semilunar valves prevent backflow from arteries into ventricles during relaxation.

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    Why does the left ventricle have higher pressure than the right?

    The left ventricle generates higher pressure than the right ventricle because it pumps blood to the entire body, while the right ventricle pumps blood only to the lungs.

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    How does pressure affect blood flow between the left atrium and ventricle?

    The pressure difference between the left atrium and left ventricle causes blood to flow from the atrium to the ventricle during diastole. This pressure difference is reversed during systole, causing blood to flow from the ventricle to the aorta.

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    Describe the valve status during isovolumetric contraction.

    During isovolumetric ventricular contraction, the left AV valve is closed, and the aortic semilunar valve is also closed. This phase occurs when the ventricle is contracting but hasn't ejected any blood yet.

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    Describe valve status during ventricular filling.

    During ventricular filling, the left AV valve is open, and the aortic semilunar valve is closed. This allows blood to flow from the atrium into the ventricle during relaxation.

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    Describe the valve status during ventricular ejection.

    When the ventricle is ejecting blood, the left AV valve is closed, and the aortic semilunar valve is open. This allows blood to be pumped from the ventricle into the aorta.

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    Define pressure in the cardiovascular system.

    Pressure is the force exerted on a surface area. It is measured in units like mmHg, torr, or pascals.

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    Define flow in the cardiovascular system.

    Flow is the movement of fluid along a pressure gradient, from high pressure to low pressure.

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    What is Poiseuille's law?

    Blood flow through a vessel is directly proportional to the pressure gradient and inversely proportional to the resistance.

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    What is the strongest contributor to flow resistance?

    Vessel diameter is the most important factor determining blood flow resistance. Doubling the diameter increases flow 16 fold.

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    What are the two main circuits of the cardiovascular system?

    The heart is a two-pump system, with the systemic circuit delivering oxygenated blood to the body and the pulmonary circuit delivering deoxygenated blood to the lungs.

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    What is the role of valves in the cardiovascular system?

    Valves in the heart ensure unidirectional blood flow, preventing backflow and maintaining efficient circulation.

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    What is blood flow?

    The term used to describe the volume of blood passing through a point in the system per unit time.

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    Pressure-Flow Relationship

    Pressure decreases as the fluid flows over distance.

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    Pressure Difference in Ventricles

    The left ventricle generates higher pressure to move blood through the larger, more resistive systemic circulation compared to the pulmonary circulation.

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    Factors Affecting Resistance

    Viscosity, length, and diameter of vessels all influence resistance to blood flow.

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    Poiseuille's Law

    The relationship between flow (Q), pressure difference (ΔP), and resistance (R) is described by Poiseuille's law: Q = ΔP/R.

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    Function of Arteries

    Arteries transport high-pressure blood to all body parts.

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    Function of Arterioles

    Arterioles regulate blood flow to capillaries by adjusting their diameter.

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    Function of Capillaries

    Capillaries facilitate the exchange of nutrients, gases, and waste between blood and tissues.

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    Function of Venules and Veins

    Venules and veins collect deoxygenated blood from capillaries and return it to the heart.

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    Sympathetic Nervous System

    The sympathetic nervous system prepares the body for "fight or flight" by increasing heart rate, blood pressure, and blood sugar.

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    Parasympathetic Nervous System

    The parasympathetic nervous system promotes "rest and digest" by slowing heart rate, lowering blood pressure, and increasing digestion.

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    RAAS (Renin-Angiotensin-Aldosterone System)

    A system involving hormones that regulate blood pressure and fluid balance. Important hormones include renin, angiotensin, and aldosterone.

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    Vasopressin (Antidiuretic Hormone)

    A hormone released by the pituitary gland that helps to regulate blood pressure and fluid balance. It increases water reabsorption by the kidneys.

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    Epinephrine

    A hormone released by the adrenal glands that increases heart rate and blood pressure.

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    Atrial Natriuretic Peptide (ANP)

    A hormone released by the heart that helps to regulate blood volume and blood pressure. It promotes sodium and water loss in urine.

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    Cardiac Output

    The volume of blood pumped by the heart each minute.

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    Flow (Q)

    The volume of blood that flows past a given point in the cardiovascular system in a given time. For laminar flow, it is determined by pressure difference and resistance according to Poiseuille's law.

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    Study Notes

    Cardiovascular Physiology

    • Animal Systems II: Course name and code (VEM 5111G)
    • Course Coordinator: Carl Hansen, PhD
    • Office: V2-163
    • Phone: (Information unavailable)
    • Email: [email protected]
    • Office Hours: By appointment (via email)
    • Course Materials: Available on e-learning

    E-learning Resources

    • Syllabus, Calendar & Lecture Notes: Available on e-learning
    • Power Points: Posted before each lecture
    • Supplemental Websites: Links provided for extra resources
    • Physiology Textbook: Link to textbook in syllabus or course materials
    • Physiology Textbooks: Copies available in VET library

    Modules

    • Seven Modules: Cover various aspects of cardiovascular physiology
    • Module 1: Introduction to the Cardiovascular System
    • Module 2: Electrical Activity of the Heart
    • Module 3: Cardiac Contractility, Cardiac Cycle, and Cardiac Output
    • Module 4: ECG Analysis and Interpretation
    • Module 5: Histology and Development
    • Module 6: The Circulation
    • Module 7: System Control & Integration

    Schedule

    • Cardiovascular Function and Control: Dr. Hansen
    • Clinical ECG: Dr. Aherne (Electrocardiography)
    • Clinical Skills Lab ECG: Dr. Aherne (Practical application, measurement, discussion)
    • Cardiovascular Histology: Dr. Pierezan (Lecture and lab)
    • Cardiovascular Embryology and Development: Dr. Tevosian

    Course Grading

    • ECG Lab Attendance & Participation: 5% of total grade
    • Four Canvas Quizzes: 10% of total grade
    • Final Exam: 85% of total grade
    • Clinical Correlate Questions: Included on the final exam

    Learning Objectives (Introduction to Cardiovascular System)

    • Basic Components: Identify and understand how they are integrated in the cardiovascular system
    • Pressure & Flow: Identify the relationship between pressure and flow in the cardiovascular system

    Cardiovascular Disease Statistics

    • Americans: 1 in 4 will develop cardiovascular disease
    • Dogs: Estimated 1 in 3 dogs will develop heart disease by 13 years old
    • Symptoms: Cardiovascular disease often progresses without obvious symptoms initially

    Cardiovascular System Function

    • Main Function: Continuously distribute blood throughout the body, delivering nutrients and removing wastes
    • Divisions: Systemic and Pulmonary
    • Flow: Unidirectional, adjusts to tissue demands
    • Cardiac Output: Key measure; volume of blood pumped per unit time (Humans: 5L/min; Dogs: 2.5 L/min)

    Structure of the Cardiovascular System

    • Four Functional Components: Pump, Distribution System, Exchange Region, Collection System and function in detail
    • Pump: Left and Right Ventricles
    • Distribution System: Arterial Tree (Systemic Arteries & Pulmonary Arteries)
    • Exchange Region: Capillaries (Systemic & Pulmonary)
    • Collection System: Venous Tree (Atria during ventricular systole)

    The Heart (Function & Flow)

    • Anatomy: One structure, two separate pumps (atrium and ventricle) each side
    • Mechanical & Electrical Interdependence: Both pumps work together for proper function
    • Flow Mechanism: Generated by the heart’s pumping action

    Valves (Unidirectional Flow)

    • Ventricular Input (AV valves): Mitral and Tricuspid prevent backflow into atria
    • Ventricular Output (Semilunar Valves): Aortic and Pulmonic prevent backflow into ventricles
    • Valve Function: Open and close passively based on pressure gradients

    Heart Function (Diastole & Systole)

    • Diastole: Relaxation phase (Aortic > Ventricular pressure, Left atrium > Left ventricle pressure)
    • Systole: Contraction phase (Ejection when Aortic < Ventricular pressure, Left atrium < Left ventricle pressure)
    • Valve Status: Detailed valve status during each phase

    Pressure & Flow

    • Pressure: Application of force to a surface; amount of force per unit area.
    • Flow: Movement of fluid down a pressure gradient.
    • Left vs. Right Ventricle Pressure: The left ventricle generates higher pressure than the right due to higher resistance
    • Resistance (Forces Opposing Flow): Friction and deflection forces result in a decrease in pressure through vessels, dependent on Viscosity, Length and Diameter of the vessel

    Systemic and Pulmonary Circulation

    • Systemic (Left) Pump: Must generate higher pressure compared to pulmonary to meet demands from larger surface area and higher resistance. Its larger mass also allows for this.
    • Factors Affecting Resistance: Viscosity, length and vessel diameter
    • Poiseuille's law: Mathematical relation describing flow in a pipe

    Vascular System (Distribution System)

    • Function: Transport metabolic substrates to tissues, removing metabolic waste products
    • Arteries: High-pressure flow to all regions, robust, elastic walls
    • Arterioles: Regulate perfusion pressure to tissues, thick less elastic walls, regulate vasoconstriction, vasodilation.
    • Capillary Beds: Exchange occurs, very thin, porous to allow exchange between blood and interstitial fluid
    • Venules & Veins: Collect blood from capillaries, serve as reservoirs (thin walled and highly compliant) to regulate pressure between arteries and heart

    Capillary Exchange

    • Location: Capillaries
    • Composition: Single layer of endothelial cells; no muscular wall, typically porous
    • Function: Facilitates exchange between blood and interstitial fluid
    • Lymphatic System: Plays a part in maintaining fluid balance

    Cardiovascular Regulation

    • Function: Maintaining blood pressure and adjusting cardiac output to meet tissue demands.
    • Intrinsic Mechanisms: Frank-Starling law of the heart, myogenic vascular smooth muscle.
    • Autonomic Mechanisms: Sympathetic, Parasympathetic Nervous System
    • Hormonal Regulation: RAAS (renal angiotensin system), Vasopressin (antidiuretic hormone), Epinephrine, Atrial natriuretic protein

    Cardiovascular Disease

    • Failure: Inadequate delivery of nutrients and O2, and inadequate removal of metabolic wastes and CO2 from tissues.
    • Cardiac Pathologies: Pump dysfunction, valve failure, myocardium dysfunction, conduction disturbances.
    • Vascular Dysfunction: Atherosclerosis, hypertension, embolisms, ischemic attacks, hemorrhage

    Valve Dysfunction (Veterinary Problems)

    • Common Problem: Valve dysfunction
    • Unidirectional flow issue: Valves prevent backflow of blood.

    Flow

    • Definition: Volume of blood moving past a point in the cardiovascular system per unit time.
    • Methods of calculation: Based on pressure gradient and the resistance offered to flow (Poiseuille's law)
    • Cardiac Output: Measured in L/min
    • Human vs. Canine: Typical human and canine cardiac output values (amount of blood pumped per minute)

    Relationship between Pressure and Flow

    • Blood Pressure (BP): Measurement of the cardiac force generating flow
    • Flow Gradient: Proportional to the pressure gradient between two points (not absolute pressure)
    • Simplified Poiseuille's Law: Flow (Q) = Pressure Gradient (ΔP) / Resistance (R)

    Resistance

    • Definition: Force opposing flow, caused by friction and deflection.
    • Factors Affecting Resistance: Length, Viscosity, and Vessel Diameter
    • Relationship to Flow: Flow is inversely proportional to resistance

    Measurement of BP

    • Historical: First measurement done on a horse (1733) by Reverend Stephen Hales.

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    Test your knowledge on the essential concepts and modules related to cardiovascular physiology. This quiz will cover topics including the heart's electrical activity, functions of the cardiovascular system, and grading components of the course. Enhance your understanding of cardiovascular health and disease.

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