Podcast
Questions and Answers
What is the main function of pheromones in animal species?
What is the main function of pheromones in animal species?
Which of the following is NOT a major chemical class of hormones?
Which of the following is NOT a major chemical class of hormones?
How do lipid-soluble hormones travel in the bloodstream?
How do lipid-soluble hormones travel in the bloodstream?
Where do lipid-soluble hormones bind to receptors?
Where do lipid-soluble hormones bind to receptors?
Signup and view all the answers
What is the term for the chain of events that converts a hormone signal to an intracellular response?
What is the term for the chain of events that converts a hormone signal to an intracellular response?
Signup and view all the answers
What is a possible response to hormone binding in target cells?
What is a possible response to hormone binding in target cells?
Signup and view all the answers
How do water-soluble hormones travel in the bloodstream?
How do water-soluble hormones travel in the bloodstream?
Signup and view all the answers
Where do water-soluble hormones bind to receptors?
Where do water-soluble hormones bind to receptors?
Signup and view all the answers
What is a characteristic feature of endocrine glands?
What is a characteristic feature of endocrine glands?
Signup and view all the answers
What is the role of secretin in the duodenum?
What is the role of secretin in the duodenum?
Signup and view all the answers
What determines the different effects of a hormone on target cells?
What determines the different effects of a hormone on target cells?
Signup and view all the answers
What is a characteristic of simple endocrine pathways?
What is a characteristic of simple endocrine pathways?
Signup and view all the answers
What is the difference between endocrine and exocrine glands?
What is the difference between endocrine and exocrine glands?
Signup and view all the answers
What is the role of the pancreas in the duodenum?
What is the role of the pancreas in the duodenum?
Signup and view all the answers
What is a characteristic of hormone pathways?
What is a characteristic of hormone pathways?
Signup and view all the answers
What is the 'fight-or-flight' response?
What is the 'fight-or-flight' response?
Signup and view all the answers
What is the function of the hypothalamus in endocrine signaling?
What is the function of the hypothalamus in endocrine signaling?
Signup and view all the answers
What is the role of the posterior pituitary?
What is the role of the posterior pituitary?
Signup and view all the answers
Which hormone regulates physiology and behavior?
Which hormone regulates physiology and behavior?
Signup and view all the answers
What is the role of the anterior pituitary hormones in hormone cascades?
What is the role of the anterior pituitary hormones in hormone cascades?
Signup and view all the answers
What is the function of prolactin-releasing hormone from the hypothalamus?
What is the function of prolactin-releasing hormone from the hypothalamus?
Signup and view all the answers
Which of the following is an example of a hormone cascade?
Which of the following is an example of a hormone cascade?
Signup and view all the answers
What is the role of oxytocin?
What is the role of oxytocin?
Signup and view all the answers
What is the relationship between the hypothalamus and the pituitary gland?
What is the relationship between the hypothalamus and the pituitary gland?
Signup and view all the answers
What is the primary function of a neurosecretory cell in a simple neuroendocrine pathway?
What is the primary function of a neurosecretory cell in a simple neuroendocrine pathway?
Signup and view all the answers
What is the response to the initial stimulus in a negative feedback loop?
What is the response to the initial stimulus in a negative feedback loop?
Signup and view all the answers
What is the role of oxytocin in the example of a simple neuroendocrine pathway?
What is the role of oxytocin in the example of a simple neuroendocrine pathway?
Signup and view all the answers
What is the primary function of the endocrine organs in the brain?
What is the primary function of the endocrine organs in the brain?
Signup and view all the answers
What triggers the release of ecdysteroid in the prothoracic gland?
What triggers the release of ecdysteroid in the prothoracic gland?
Signup and view all the answers
What is the response to the release of oxytocin in mammals?
What is the response to the release of oxytocin in mammals?
Signup and view all the answers
What is required for metamorphosis to occur in invertebrates?
What is required for metamorphosis to occur in invertebrates?
Signup and view all the answers
What is the primary function of PTTH in invertebrates?
What is the primary function of PTTH in invertebrates?
Signup and view all the answers
What is the response of the hypothalamus when thyroid hormone levels drop in the blood?
What is the response of the hypothalamus when thyroid hormone levels drop in the blood?
Signup and view all the answers
What is the result of low levels of thyroid hormone due to insufficient iodine?
What is the result of low levels of thyroid hormone due to insufficient iodine?
Signup and view all the answers
What is the primary function of growth hormone (GH) in the body?
What is the primary function of growth hormone (GH) in the body?
Signup and view all the answers
What is the consequence of an excess of growth hormone (GH) in the body?
What is the consequence of an excess of growth hormone (GH) in the body?
Signup and view all the answers
What is the primary function of parathyroid hormone (PTH) in the body?
What is the primary function of parathyroid hormone (PTH) in the body?
Signup and view all the answers
What is the result of the hypothalamus secreting thyrotropin-releasing hormone (TRH)?
What is the result of the hypothalamus secreting thyrotropin-releasing hormone (TRH)?
Signup and view all the answers
What is the only iodine-containing molecule synthesized in the body?
What is the only iodine-containing molecule synthesized in the body?
Signup and view all the answers
What is the consequence of a lack of growth hormone (GH) in the body?
What is the consequence of a lack of growth hormone (GH) in the body?
Signup and view all the answers
Study Notes
Signaling by Pheromones
- Pheromones are chemicals released into the environment by some animal species to communicate with each other.
- Pheromones serve various functions, including:
- Marking trails leading to food
- Defining territories
- Warning of predators
- Attracting potential mates
Hormone Chemical Classes
- Hormones can be classified into three major chemical classes:
- Polypeptides
- Steroids
- Amines
- Polypeptides and most amines are water-soluble, while steroid hormones and other non-polar hormones are lipid-soluble.
Cellular Hormone Response Pathways
- Water-soluble hormones are secreted by exocytosis, travel freely in the bloodstream, and bind to cell-surface receptors.
- Lipid-soluble hormones diffuse across cell membranes, travel in the bloodstream bound to transport proteins, and diffuse through the membrane of target cells.
- They bind to receptors in the cytoplasm or nucleus of the target cells.
Response Pathway for Water-Soluble Hormones
- Binding of a hormone to its receptor initiates a cellular response.
- The response may be:
- Activation of an enzyme
- Change in uptake or secretion of certain molecules
- Rearrangement of the cytoskeleton
- Initiation of changes in transcription of certain genes
- Signal transduction is the process by which the chemical signal is converted to an intracellular response.
Multiple Responses to a Single Hormone
- The same hormone can have different effects on target cells that have:
- Different receptors for the hormone
- Different signal transduction pathways
- For example, the hormone epinephrine has multiple effects that form the basis of the “fight-or-flight” response.
Endocrine Tissues and Organs
- Endocrine cells are often grouped in ductless organs called endocrine glands, such as:
- Thyroid and parathyroid glands
- Testes or ovaries
- In contrast, exocrine glands, such as salivary glands, have ducts to carry secreted substances onto body surfaces or into body cavities.
Feedback Regulation and Coordination with the Nervous System
- Hormones are assembled into regulatory pathways that involve feedback regulation and coordination with the nervous system.
- In a simple endocrine pathway, endocrine cells respond directly to a stimulus by secreting a particular hormone.
- The hormone travels in the bloodstream to target cells, where it interacts with its specific receptors, and signal transduction within target cells brings about a physiological response.
Simple Neuroendocrine Pathways
- In a simple neuroendocrine pathway, the stimulus is received by a sensory neuron, which stimulates a neurosecretory cell.
- The neurosecretory cell secretes a neurohormone, which enters the bloodstream and travels to target cells.
Feedback Regulation
- In a negative feedback loop, the response reduces the initial stimulus.
- For example, the increase in pH in the intestine caused by secretin release shuts off further secretin release.
- Positive feedback reinforces a stimulus to produce an even greater response.
- For example, in mammals, oxytocin causes the release of milk, causing greater suckling by offspring, which stimulates the release of more oxytocin.
Coordination of Endocrine and Nervous Systems
- In a wide range of animals, endocrine organs in the brain integrate the function of the endocrine system with that of the nervous system.
- The hypothalamus coordinates endocrine signaling, receives information from nerves throughout the body, and initiates appropriate neuroendocrine signals.
- Signals from the hypothalamus travel to the pituitary gland, composed of the posterior pituitary and anterior pituitary.
Posterior Pituitary Hormones
- Neurosecretory cells of the hypothalamus synthesize the two posterior pituitary hormones:
- Antidiuretic hormone (ADH) regulates physiology and behavior
- Oxytocin regulates milk secretion by the mammary glands
Anterior Pituitary Hormones
- The anterior pituitary controls diverse processes, such as metabolism, osmoregulation, and reproduction.
- Hormones secreted by the hypothalamus control the release of all anterior pituitary hormones.
- For example, prolactin-releasing hormone from the hypothalamus stimulates the anterior pituitary to secrete prolactin (PRL), which has a role in milk production.
Hormone Cascades
- Sets of hormones from the hypothalamus, anterior pituitary, and a target endocrine gland are often organized into a hormone cascade.
- The anterior pituitary hormones in these pathways are called tropic hormones.
- Thyroid hormone regulates many functions, and low levels of thyroid hormone in the blood stimulate the hypothalamus to secrete thyrotropin-releasing hormone (TRH), causing the anterior pituitary to secrete thyroid-stimulating hormone (TSH).
Disorders of Thyroid Function and Regulation
- Disruption of thyroid hormone production and regulation can result in serious disorders.
- Thyroid hormone is the only iodine-containing molecule synthesized in the body.
- With low levels of thyroid hormone, due to insufficient iodine, the pituitary continues to secrete TSH, causing the thyroid to enlarge, resulting in a goiter, a marked swelling of the neck.
Hormonal Regulation of Growth
- Growth hormone (GH) is secreted by the anterior pituitary gland, and has tropic and nontropic effects.
- The liver, a major target, responds to GH by releasing insulin-like growth factors (IGFs), which stimulate bone and cartilage growth.
- An excess of GH can cause gigantism, while a lack of GH can cause dwarfism.
Parathyroid Hormone and Vitamin D: Control of Blood Calcium
- Homeostatic regulation of calcium (Ca2+) in the blood is vital.
- In mammals, parathyroid hormone (PTH) is released by the parathyroid glands when Ca2+ levels fall below a set point.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Related Documents
Description
Learn about the role of pheromones in animal communication, including marking trails, defining territories, and attracting mates. Also, explore the chemical classes of hormones.