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Questions and Answers

What is a primary characteristic of an open circulatory system?

  • Organs are directly bathed in hemolymph. (correct)
  • Blood passes through the heart twice in each circuit.
  • Blood is enclosed within a network of vessels.
  • Blood flows in one direction due to a series of valves.

Which of the following organisms typically possess an open circulatory system?

  • Birds
  • Mammals
  • Insects (correct)
  • Fish

What is the primary advantage of a closed circulatory system compared to an open circulatory system?

  • Lower metabolic demands
  • Slower blood flow
  • More efficient and controlled blood flow (correct)
  • Direct immersion of organs in blood

In a single circulatory system, where does blood flow after being pumped from the heart?

<p>To the gills for oxygenation, then to the body. (D)</p> Signup and view all the answers

What is the main characteristic of a double circulatory system?

<p>Blood flows through the heart twice in each complete circuit. (A)</p> Signup and view all the answers

Which two circuits are involved in a double circulatory system?

<p>Systemic and pulmonary circuits (A)</p> Signup and view all the answers

What is the role of the pulmonary circulation in the human circulatory system?

<p>To send deoxygenated blood to the lungs to receive oxygen (C)</p> Signup and view all the answers

From which chamber of the heart does blood get pumped into the pulmonary artery?

<p>Right ventricle (B)</p> Signup and view all the answers

Which vessels carry oxygen-rich blood from the lungs back to the heart?

<p>Pulmonary veins (C)</p> Signup and view all the answers

Which vessel does the left ventricle pump blood into for systemic circulation?

<p>Aorta (B)</p> Signup and view all the answers

Why is the closed circulatory system more suitable for larger and more active animals?

<p>It provides faster blood flow and better regulation of blood distribution. (D)</p> Signup and view all the answers

What is the cardiovascular system responsible for?

<p>Transporting nutrients, oxygen, and hormones (C)</p> Signup and view all the answers

Which type of circulation involves blood passing through the heart only once per complete circuit?

<p>Single circulation (B)</p> Signup and view all the answers

Which vertebrates exhibit a double circulation pathway?

<p>Amphibians, reptiles, birds, and mammals (C)</p> Signup and view all the answers

What is the function of the systemic circulation?

<p>Carrying oxygenated blood to all parts of the body (B)</p> Signup and view all the answers

What is the lymphatic system often referred to as?

<p>Secondary circulatory system (C)</p> Signup and view all the answers

What is the primary function of lymph nodes?

<p>To filter lymph and trap bacteria (B)</p> Signup and view all the answers

Which of the following is a key function of the lymphatic system?

<p>Returning excess interstitial fluid to the bloodstream (D)</p> Signup and view all the answers

What relies on muscle movements and valves to transport lymph?

<p>Lymphatic system (B)</p> Signup and view all the answers

Where is the heart positioned in the human body?

<p>In the thorax, behind the sternum and between the lungs (B)</p> Signup and view all the answers

What minimizes friction and facilitates the heart's movement during contraction?

<p>Pericardial fluid (D)</p> Signup and view all the answers

What type of muscle is the myocardium composed of?

<p>Striated cardiac muscle (A)</p> Signup and view all the answers

What ensures unidirectional blood flow within the heart?

<p>Valves (B)</p> Signup and view all the answers

What is the role of the superior and inferior vena cava?

<p>Transporting deoxygenated blood to the right atrium (D)</p> Signup and view all the answers

Which vessel does blood flow through to get oxygenated in the lungs?

<p>Pulmonary artery (D)</p> Signup and view all the answers

What condition arises when coronary arteries are obstructed by plaques?

<p>Heart attack (Myocardial Infarction) (D)</p> Signup and view all the answers

What defines hypertension?

<p>Persistently high blood pressure (≥140/90 mm Hg) (C)</p> Signup and view all the answers

What can hypotension lead to in severe cases?

<p>Shock (C)</p> Signup and view all the answers

Which node generates an electrical impulse that causes the atria to contract?

<p>Sinoatrial (SA) node (C)</p> Signup and view all the answers

During which phase of the cardiac cycle do both the atria and ventricles relax?

<p>Diastole (A)</p> Signup and view all the answers

What is the natural pacemaker of the heart?

<p>SA node (B)</p> Signup and view all the answers

How does increased cellular respiration influence heartbeat?

<p>It raises CO2 levels, stimulating receptors to increase heart rate. (D)</p> Signup and view all the answers

How does physical activity affect blood volume returning to the right atrium?

<p>It promotes higher blood volume, stimulating the heart to beat faster. (A)</p> Signup and view all the answers

Given a patient diagnosed with a heart condition that necessitates a procedure to ensure unidirectional blood flow, which intervention would directly address this?

<p>Performing a valve replacement surgery to correct valve malfunction. (A)</p> Signup and view all the answers

A researcher is studying the effects of a novel drug on the cardiac cycle. They observe that the duration of ventricular systole is significantly prolonged without affecting atrial systole or diastole. What is the most likely direct effect of this drug?

<p>Reduced cardiac output due to inefficient ventricular filling. (A)</p> Signup and view all the answers

In which type of circulatory system does blood directly bathe the organs?

<p>Open circulatory system (A)</p> Signup and view all the answers

Which of the following is a primary characteristic of a closed circulatory system?

<p>Blood contained within vessels (D)</p> Signup and view all the answers

An insect's circulatory system is best described as:

<p>Open and single (B)</p> Signup and view all the answers

What is the primary limitation of a single circulatory system compared to a double circulatory system?

<p>Lower blood pressure after passing through the respiratory organs (A)</p> Signup and view all the answers

In a double circulatory system, what is the role of the systemic circuit?

<p>To carry oxygenated blood to the body tissues (B)</p> Signup and view all the answers

Which heart chamber receives oxygenated blood from the lungs in the human circulatory system?

<p>Left atrium (C)</p> Signup and view all the answers

What is the function of the lymphatic system that most directly complements the cardiovascular system?

<p>Returning interstitial fluid to the bloodstream (C)</p> Signup and view all the answers

Lymph nodes play a critical role in the lymphatic system by:

<p>Filtering lymph and trapping pathogens (B)</p> Signup and view all the answers

Which component is NOT part of the lymphatic system?

<p>Aorta (A)</p> Signup and view all the answers

The heart is located in the:

<p>Thoracic cavity (A)</p> Signup and view all the answers

What is the role of the pericardial fluid?

<p>To reduce friction during heart contractions (A)</p> Signup and view all the answers

The myocardium is primarily composed of:

<p>Cardiac muscle (B)</p> Signup and view all the answers

Heart valves function to ensure:

<p>Unidirectional blood flow (A)</p> Signup and view all the answers

Deoxygenated blood from the body enters the heart through which vessels?

<p>Superior and inferior vena cava (D)</p> Signup and view all the answers

In pulmonary circulation, blood flows to the lungs via the:

<p>Pulmonary artery (C)</p> Signup and view all the answers

Myocardial infarction, commonly known as a heart attack, is primarily caused by:

<p>Blockage of coronary arteries (C)</p> Signup and view all the answers

Hypertension is clinically defined as blood pressure at or above:

<p>140/90 mm Hg (D)</p> Signup and view all the answers

Severe hypotension can lead to:

<p>Shock (C)</p> Signup and view all the answers

The sinoatrial (SA) node initiates atrial contraction by:

<p>Generating an electrical impulse (D)</p> Signup and view all the answers

During diastole, which of the following events occurs in the heart?

<p>Both atria and ventricles relax (D)</p> Signup and view all the answers

What is the primary function of the atrioventricular (AV) node in the cardiac cycle?

<p>To delay and relay the electrical impulse to the ventricles (D)</p> Signup and view all the answers

Increased cellular respiration during exercise leads to elevated CO2 levels, which, in turn, cause:

<p>Increased heart rate (C)</p> Signup and view all the answers

How does increased blood volume returning to the right atrium affect heartbeat?

<p>It speeds up the heartbeat (D)</p> Signup and view all the answers

Which phase of the cardiac cycle immediately follows ventricular systole?

<p>Diastole (general relaxation) (A)</p> Signup and view all the answers

If the sinoatrial node fails to function correctly, what is the most likely direct consequence?

<p>The heart will beat at a slower and irregular rhythm (D)</p> Signup and view all the answers

Consider a scenario where the semilunar valves are incompetent. What would be the immediate effect on blood flow?

<p>Blood would flow back from the arteries into the ventricles. (B)</p> Signup and view all the answers

A patient presents with chest pain due to reduced blood flow to the myocardium, but without complete blockage of coronary arteries. This condition is most likely:

<p>Angina pectoris (D)</p> Signup and view all the answers

Which of the following accurately describes the sequence of blood flow through the heart and lungs?

<p>Right atrium → right ventricle → pulmonary arteries → lungs → pulmonary veins → left atrium → left ventricle (B)</p> Signup and view all the answers

If a drug increases the duration of atrial systole without affecting ventricular systole or diastole, what direct effect would this have on the cardiac cycle?

<p>Increased ventricular filling time (A)</p> Signup and view all the answers

Compared to the cardiovascular system, the lymphatic system:

<p>Is an open system that aids in fluid balance and immunity. (A)</p> Signup and view all the answers

Consider an animal with a very low metabolic rate and limited physical activity. Which type of circulatory system would be most physiologically appropriate for this animal?

<p>An open circulatory system (B)</p> Signup and view all the answers

In the cardiac cycle, the 'dub' sound is most directly associated with:

<p>Closing of the semilunar valves (C)</p> Signup and view all the answers

A patient is diagnosed with mitral valve prolapse, affecting the valve between the left atrium and left ventricle. What is the most immediate physiological consequence?

<p>Backflow of blood into the left atrium during ventricular systole (C)</p> Signup and view all the answers

Which of the following best explains why vertebrates evolved from single to double circulatory systems?

<p>To increase the efficiency of oxygen delivery to tissues (A)</p> Signup and view all the answers

Imagine a scenario where the lymphatic vessels are blocked. Which immediate symptom would you expect to observe?

<p>Tissue edema (swelling) (B)</p> Signup and view all the answers

What is the primary fluid found in an open circulatory system?

<p>Hemolymph (C)</p> Signup and view all the answers

Which of the following is a characteristic of the blood flow in a closed circulatory system?

<p>Blood is separated from the interstitial fluid. (C)</p> Signup and view all the answers

Which animal group possesses a circulatory system where blood passes through the heart only once per circuit?

<p>Fish (B)</p> Signup and view all the answers

In a double circulatory system, what is the purpose of the blood passing through the lungs?

<p>To exchange carbon dioxide for oxygen (B)</p> Signup and view all the answers

What is the vessel that transports oxygenated blood from the lungs to the heart?

<p>Pulmonary vein (B)</p> Signup and view all the answers

What is the primary role of the cardiovascular system?

<p>Transporting nutrients and gases (A)</p> Signup and view all the answers

Which of the following components is NOT a primary function of the lymphatic system?

<p>Transporting oxygen to body tissues (D)</p> Signup and view all the answers

Which structure encases the heart, providing lubrication to minimize friction during contraction?

<p>Pericardium (B)</p> Signup and view all the answers

What is the most direct consequence of damaged or incompetent heart valves?

<p>Backflow of blood (B)</p> Signup and view all the answers

From which chamber does blood get pumped out to the systemic circulation?

<p>Left ventricle (D)</p> Signup and view all the answers

Which of these statements best describes blood flow through the heart's chambers?

<p>Blood flows from the atria to the ventricles. (D)</p> Signup and view all the answers

What is the underlying cause of a myocardial infarction?

<p>Obstruction of coronary arteries (A)</p> Signup and view all the answers

Which electrical event initiates the ventricular contraction phase of the cardiac cycle?

<p>Activation of the atrioventricular (AV) node (D)</p> Signup and view all the answers

During diastole, what action allows the atria to fill with blood?

<p>All heart chambers are relaxed. (D)</p> Signup and view all the answers

How does increased blood volume returning to the right atrium primarily influence heart rate?

<p>It stimulates stretch receptors, increasing heart rate. (B)</p> Signup and view all the answers

What is the most likely effect on the cardiovascular system of a drug that prolongs ventricular systole without affecting atrial systole or diastole?

<p>Reduced ventricular filling time (A)</p> Signup and view all the answers

If a patient's sinoatrial (SA) node is not functioning correctly, what direct effect would this have on the cardiac cycle?

<p>The heart rate would become irregular or slower. (C)</p> Signup and view all the answers

How does the lymphatic system's function most directly complement the cardiovascular system?

<p>Returning interstitial fluid to the bloodstream (B)</p> Signup and view all the answers

What is the physiological consequence of a complete blockage of the lymphatic vessels in a specific region of the body?

<p>Edema (swelling) due to fluid accumulation (C)</p> Signup and view all the answers

Which statement accurately describes the impact of exercise on the cardiovascular system functionality?

<p>Increases cardiac output and venous return (C)</p> Signup and view all the answers

A researcher discovers a new species with a circulatory system where blood pressure in the systemic circuit is significantly lower than in the pulmonary circuit. What adaptation would MOST likely compensate for this?

<p>Increased red blood cell count to enhance oxygen carrying capacity (D)</p> Signup and view all the answers

A novel drug selectively inhibits the function of the atrioventricular bundle (bundle of His). What would be the MOST immediate and direct effect on the cardiac cycle?

<p>Ventricular contraction would be uncoordinated or absent (A)</p> Signup and view all the answers

What is the primary advantage of a closed circulatory system over an open circulatory system with respect to oxygen delivery to tissues?

<p>Closed systems allow for more precise control of blood flow to specific tissues based on immediate metabolic needs. (C)</p> Signup and view all the answers

Why is hypertension a significant risk factor for cardiovascular diseases such as stroke and myocardial infarction?

<p>Hypertension increases the workload on the heart and damages arterial walls, promoting atherosclerosis and clot formation. (C)</p> Signup and view all the answers

Which adaptation would mostly offset the impact of lowered oxygen solubility in blood?

<p>An increase in blood volume (D)</p> Signup and view all the answers

How would you describe blood circulation in amphibians?

<p>Amphibians have double circulation, but with some mixing of oxygenated and deoxygenated blood. (B)</p> Signup and view all the answers

Which of the following accurately describes the roles and functional designs of arteries and veins?

<p>Arteries carry blood away from the heart and have thicker, more elastic walls, while veins return blood to the heart and have valves. (C)</p> Signup and view all the answers

What immediate impact to blood distribution would leaky tricuspid and bicuspid valves have?

<p>Increased atrial pressure during ventricular contraction and reduced systemic blood flow. (D)</p> Signup and view all the answers

What physiological process would be affected most from blocked lymphatic vessels?

<p>Interstitial fluid balance. (C)</p> Signup and view all the answers

During vigorous exercise, how do local metabolic changes affect blood distribution to muscles?

<p>Local vasodilation and increased capillary permeability enhance oxygen delivery and waste removal. (C)</p> Signup and view all the answers

What condition would be MOST indicative of heart failure?

<p>Edema in the extremities, shortness of breath, and persistent fatigue. (C)</p> Signup and view all the answers

Atherosclerosis is characterized by which circulatory process?

<p>Plaque build up in arteries. (D)</p> Signup and view all the answers

If both the baroreceptors are damaged, which bodily function would be destabilized?

<p>Blood pressure. (C)</p> Signup and view all the answers

Considering the evolutionary pressures favoring closed circulatory systems, which aspect of cellular metabolism would be MOST directly enhanced compared to organisms with open systems?

<p>Precise regional control of oxygen delivery optimizing oxidative phosphorylation efficiency (D)</p> Signup and view all the answers

In the context of comparative cardiovascular physiology, which evolutionary adaptation MOST significantly contributes to the ability of endothermic vertebrates to sustain high levels of physical activity compared to ectothermic vertebrates?

<p>The complete separation of pulmonary and systemic circulation minimizing blood mixing (D)</p> Signup and view all the answers

If a hypothetical pharmaceutical agent selectively ablates the lymphatic capillaries, what immediate physiological consequence would MOST directly compromise tissue homeostasis?

<p>Accumulation of protein-rich interstitial fluid leading to edema (B)</p> Signup and view all the answers

In a patient presenting with chronic lymphedema following radical lymph node dissection, which long-term cellular adaptation would MOST likely exacerbate the condition?

<p>Fibroblast differentiation into myofibroblasts causing tissue fibrosis (A)</p> Signup and view all the answers

Considering the Frank-Starling mechanism, how does increased venous return MOST directly influence cardiac output at the molecular level?

<p>By optimizing overlap of actin and myosin filaments increasing the force of contraction (D)</p> Signup and view all the answers

Given a scenario involving a patient with a severely stenotic aortic valve, what compensatory mechanism would the left ventricle MOST likely undergo to maintain systemic blood pressure?

<p>Hypertrophy of the ventricular myocardium increasing wall thickness (B)</p> Signup and view all the answers

A patient undergoing a cardiac catheterization is found to have endothelial dysfunction in the coronary arteries. Which of the following molecular events is MOST likely impaired?

<p>Production of nitric oxide (NO) regulating vascular tone (A)</p> Signup and view all the answers

If a researcher discovers a novel mutation that selectively impairs the function of gap junctions in cardiac myocytes, which aspect of cardiac physiology would be MOST directly affected?

<p>The rate of action potential propagation through the ventricular myocardium (A)</p> Signup and view all the answers

Considering the renin-angiotensin-aldosterone system (RAAS), what is the MOST direct physiological effect of increased angiotensin II levels on the cardiovascular system?

<p>Increased sodium reabsorption in the collecting ducts of the nephrons (C)</p> Signup and view all the answers

In a patient with chronic heart failure, which adaptive mechanism, while initially beneficial, can ultimately contribute to the deterioration of cardiac function?

<p>Hypertrophy of cardiac myocytes increasing ventricular wall thickness (D)</p> Signup and view all the answers

Which of the following factors would MOST directly reduce afterload on the left ventricle?

<p>Dilation of aortic valve reducing outflow obstruction (C)</p> Signup and view all the answers

If a novel drug selectively blocks the activity of the Na+/Ca2+ exchanger in cardiac myocytes, what would be the MOST likely effect on cardiac contractility?

<p>Accumulation of intracellular calcium increasing contractility (C)</p> Signup and view all the answers

In a patient with a genetic defect causing impaired degradation of misfolded proteins in cardiac myocytes, which cellular process would MOST likely be disrupted, leading to dilated cardiomyopathy?

<p>Lysosomal autophagy and protein turnover (D)</p> Signup and view all the answers

Which component of the electrocardiogram (ECG) MOST directly reflects the repolarization of the ventricular myocardium?

<p>T wave (D)</p> Signup and view all the answers

In the context of blood pressure regulation, what is the MOST direct effect of atrial natriuretic peptide (ANP) on renal function?

<p>Dilation of afferent arterioles in the glomeruli (D)</p> Signup and view all the answers

What is the MOST immediate consequence of inhibiting the parasympathetic nervous system's influence on the sinoatrial (SA) node?

<p>Increased heart rate due to reduced acetylcholine release (C)</p> Signup and view all the answers

In a patient diagnosed with restrictive cardiomyopathy, which hemodynamic parameter would be MOST significantly affected during ventricular diastole?

<p>End-diastolic pressure due to increased ventricular stiffness (D)</p> Signup and view all the answers

If a researcher engineered artificial capillaries with significantly reduced permeability to albumin, what physiological consequence would MOST likely occur in the surrounding tissues?

<p>Decreased interstitial oncotic pressure leading to fluid reabsorption (C)</p> Signup and view all the answers

In the context of ischemic heart disease, which metabolic adaptation would cardiac myocytes MOST likely undergo to maintain ATP production during periods of reduced oxygen supply?

<p>Upregulation of glycolysis and lactate production (B)</p> Signup and view all the answers

What is the MOST direct molecular mechanism by which statins improve endothelial function in patients with atherosclerosis?

<p>Increased expression of endothelial nitric oxide synthase (eNOS) (B)</p> Signup and view all the answers

If a genetic mutation resulted in non-functional baroreceptors, what immediate physiological response would be compromised?

<p>Maintenance of blood pressure during postural changes (D)</p> Signup and view all the answers

In a patient with mitral valve regurgitation, what compensatory change would MOST likely occur in the left atrium over time?

<p>Dilation of the atrial chamber increasing capacity (A)</p> Signup and view all the answers

Considering the pathophysiology of heart failure with preserved ejection fraction (HFpEF), which underlying mechanism MOST directly contributes to impaired ventricular filling?

<p>Increased ventricular stiffness due to myocardial fibrosis (C)</p> Signup and view all the answers

If a novel drug selectively inhibits the activity of the L-type calcium channels in cardiac myocytes, what would be the MOST direct effect on the action potential?

<p>Shortening of the plateau phase decreasing contractility (C)</p> Signup and view all the answers

Which cellular process is MOST directly responsible for the development of collateral circulation in response to chronic coronary artery occlusion?

<p>Arteriogenesis induced by increased shear stress (C)</p> Signup and view all the answers

In a patient with advanced heart failure, what hormonal adaptation would MOST likely contribute to hyponatremia (low sodium levels)?

<p>Enhanced release of antidiuretic hormone (ADH) (D)</p> Signup and view all the answers

What is the MOST immediate effect on the cardiac cycle of a drug that selectively prolongs the inactivation of voltage-gated sodium channels in cardiac myocytes?

<p>Prolonged QRS interval on the electrocardiogram (ECG) (D)</p> Signup and view all the answers

Which of the following best represents why blood velocity decreases from the aorta to the capillaries?

<p>Total cross-sectional area of capillaries is higher than aorta (A)</p> Signup and view all the answers

What is the primary reason why the lymphatic system lacks a central pump, unlike the cardiovascular system?

<p>Lymph movement primarily depends on external compression forces. (C)</p> Signup and view all the answers

What is the primary reason for the absence of erythrocytes in lymph?

<p>Erythrocytes usually stay in their own closed vascular system. (D)</p> Signup and view all the answers

If a blood vessel has a thick layer of smooth muscle with elastic fibers, a relatively small lumen, and carries blood away from the heart, which type of vessel is it?

<p>A medium-sized artery (D)</p> Signup and view all the answers

Which of the following adaptations allow the cardiovascular system offset lowered oxygen solubility?

<p>An increased number of red blood cells (A)</p> Signup and view all the answers

Flashcards

Open Circulatory System

Blood and bodily fluids flow into an open body cavity, directly bathing organs; common in invertebrates.

Closed Circulatory System

Blood is enclosed within a network of vessels, allowing for more efficient and controlled flow; typical of vertebrates.

Single Circulatory Pathway

Blood passes through the heart once per circuit, common in fish.

Double Circulatory Pathway

Blood passes through the heart twice per circuit, allowing for higher pressure and faster flow, found in mammals and birds.

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Pulmonary Circulation

Part of the double circulatory system carrying deoxygenated blood to the lungs and oxygenated blood back to the heart.

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Systemic Circulation

Part of the double circulatory system distributing oxygenated blood to the body tissues and returning deoxygenated blood to the heart.

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Cardiovascular System

Transports nutrients, oxygen, hormones, and blood cells throughout the body.

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Lymphatic System

Drains lymph from tissues into the blood; important for immune response.

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Lymph

Clear fluid that removes bacteria, waste, and excess water from tissues.

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Lymph Nodes

Filters lymph, trapping bacteria and microorganisms.

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Lymph Organs

Spleen and thymus; produce and mature lymphocytes.

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Apex (Heart)

Pointed end of the heart, directed towards the left.

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Pericardium

Double-layered sac encasing the heart, containing fluid to reduce friction.

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Myocardium

Striated cardiac muscle forming the bulk of the heart.

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Endocardium

Smooth epithelial layer lining the interior of the heart's chambers.

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Atria

Upper chambers of the heart that receive blood.

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Ventricles

Lower chambers of the heart that pump blood out.

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Heart Valves

Ensure unidirectional blood flow and prevent backflow in the heart.

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Vena Cava

Transport deoxygenated blood from the body to the right atrium.

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Pulmonary Veins

Carry oxygenated blood from the lungs to the left atrium.

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Aorta

Pumps oxygen-rich blood from the left ventricle to the body.

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Heart Attack (Myocardial Infarction)

Occurs when coronary arteries are blocked, leading to cardiac muscle death.

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Hypertension

Persistently high blood pressure (≥140/90 mm Hg).

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Hypotension

Unusually low blood pressure.

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Cardiac Cycle

The sequence of events that occur during one complete heartbeat.

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Atrial Systole

Atria contract, pushing blood into the ventricles.

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Ventricular Systole

Ventricles contract, pushing blood into the aorta and pulmonary arteries.

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Diastole

Atria and ventricles relax, allowing blood to fill the atria.

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SA Node

Generates electrical impulses, acting as the heart's natural pacemaker.

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Vasovagal response

Slows heartbeat.

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Lub Dub

What the normal sound of the heartbeat represents.

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Exercise Influence on Heartbeat

Increased CO2 levels and muscular activity increase heart rate during exercise.

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Superior and Inferior Vena Cava

Returns deoxygenated blood to the right atrium.

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Pericardial Fluid

Located in the pericardium minimizing friction.

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Double circulation benefits

Includes pulmonary and systemic circuits delivering oxygenated blood to the body.

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Cardiovascular system function

The cardiovascular system uses the heart to pump blood, distributing oxygen, nutrients, and hormones.

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Lymphatic system flow

The lymphatic system relies on muscle movement to transport lymph; critical for immune response and fluid balance.

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Anchorage of the Heart

Heart's position is stabilized by these vessels, entering and exiting its broader side.

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Role of heart valves

These ensure one-way blood flow, preventing backflow during heart contractions.

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Pulmonary artery function

From the right ventricle, blood is sent to the lungs through this artery, where it gets oxygenated.

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CO2 impact on cardiac rate

Elevated carbon dioxide, sensed by receptors boosting rates.

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Anchorage of heart

The heart's position is maintained by these blood vessels, which enter and exit its broader side.

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Pulmonary artery

From the right ventricle, blood is sent to the lungs for oxygenation through this vessel.

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Hypertension risks

A disease resulting from increased resistance to blood flow in the arteries.

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Heart Covering

The double layered epithelium/sac that surrounds the heart.

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Hemolymph

The fluid that circulates in an open circulatory system, directly bathing the organs.

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Cardiac disease

Resistance is caused by plaques in the arteries.

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Pulmonary circulation flow

From the right ventricle, blood is sent to the lungs for oxygenation, then returns to the left atrium.

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Exercise heartbeat link

Increased cellular respiration raises CO2 levels, triggering receptors to signal the heart to beat faster.

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Study Notes

Circulatory Systems in Animals

  • Circulatory systems transport nutrients and oxygen to tissues while removing waste products.
  • There are two main types: open and closed.

Open Circulatory System

  • Blood flows into an open body cavity where organs are directly bathed in blood.
  • This process allows for nutrient exchange and waste removal.
  • Found in invertebrates like arthropods and mollusks.
  • Blood vessels open into an interior cavity where hemolymph moves freely.
  • Hemolymph moves via body movements and muscular contractions.
  • The lack of directional flow and reliance on slow-moving hemolymph makes the open circulatory system less efficient compared to closed systems.

Closed Circulatory System

  • Blood is enclosed within blood vessels, allowing for efficient and controlled flow.
  • Typical of vertebrates (fish, amphibians, reptiles, birds, mammals).
  • Blood is pumped by a heart through vessels reaching all body parts, then returning to the heart.
  • Provides faster blood flow and better regulation of blood distribution.

Single Circulatory Pathway

  • Blood passes through the heart once per circuit.
  • Seen in fish, where blood is pumped to the gills for oxygenation, then to the body, and back to the heart.
  • Involves one capillary bed during circulation, limiting blood pumping speed due to pressure reduction after the gills.

Double Circulatory Pathway

  • Blood passes through the heart twice per circuit.
  • Found in mammals and birds.
  • Includes pulmonary and systemic circuits.
  • Allows for higher pressure and faster blood flow.
  • The heart repressurizes blood between circuits.
  • Separation of oxygenated and deoxygenated blood ensures efficient oxygen supply.
  • Facilitated by a four-chamber heart preventing blood mixing.

Human Circulatory System

  • Divided into pulmonary (deoxygenated blood to lungs) and systemic (oxygenated blood to body tissues) circulation.
  • Blood is propelled by the heart, starting from the right ventricle to the lungs via pulmonary arteries.
  • After oxygenation, blood returns to the left atrium via pulmonary veins.
  • Oxygen-rich blood is pumped from the left ventricle to the aorta, distributing it throughout the body.

Efficiency and Location

  • Open circulatory systems are adequate for smaller, less active invertebrates due to slower hemolymph flow.
  • Closed systems support higher metabolic demands of larger, more active animals.
  • Circulatory system differences reflect evolutionary adaptations, optimizing physiological functions for survival and reproduction.

Lymphatic Circulatory System

  • Humans possess cardiovascular and lymphatic systems for maintaining tissue homeostasis and immune defense.
  • These systems are interconnected and work collaboratively.

Cardiovascular Circulatory System

  • Closed system transporting nutrients, oxygen, carbon dioxide, hormones, and blood cells.
  • Provides nourishment, fights diseases, stabilizes temperature and pH, and maintains homeostasis.

Types of Circulation within the Cardiovascular System

  • Single Circulation Pathway:
  • Found in fish.
  • The heart pumps deoxygenated blood to the gills for oxygenation and travels to the rest of the body.
  • Blood passes through the heart once per complete circuit.
  • Double Circulation Pathway:
  • Found in humans and higher vertebrates (amphibians, some reptiles, birds, and mammals).
  • Consists of pulmonary and systemic circuits.
  • Pulmonary Circulation:
  • Carries deoxygenated blood from the right side of the heart to the lungs for oxygenation and oxygenated blood back to the left side of the heart.
  • Systemic Circulation:
  • Moves oxygenated blood from the left side of the heart to the body and deoxygenated blood back to the right side of the heart.
  • The double circulation system provides vigorous blood flow due to separate circuits.

Lymphatic System

  • An open system that complements the cardiovascular system by draining lymph from tissues into the blood.
  • Often referred to as the secondary circulatory system
  • Lymph is a clear fluid removing bacteria, waste products, and excess water from tissues.

Components of the Lymphatic System

  • Lymph Vessels and Ducts: Transport lymph.
  • Lymph Nodes: Filter lymph and trap microorganisms.
  • Lymph Organs: (spleen and thymus) Produce and mature lymphocytes.

Functions of the Lymphatic System

  • Returns excess interstitial fluid to the bloodstream.
  • Absorbs and transports fatty acids and fats as chyle from the digestive system.
  • Provides an environment for lymphocyte production and maturation.

Comparison of Cardiovascular and Lymphatic Systems

  • The cardiovascular system uses the heart to pump blood through a closed network.
  • It efficiently distributes oxygen, nutrients, and hormones.
  • The lymphatic system relies on muscle movements to transport lymph in a more open system, playing a role in immune responses and fluid balance.

Cardiovascular Diseases

  • The heart is located in the thorax behind the sternum and between the lungs.
  • Apex: The pointed end of the heart directs to the left.
  • Pericardium: It is a double-layered epithelium encasing the heart, with pericardial fluid to minimize friction.
  • Anchorage: Large blood vessels entering and exiting the heart stabilize its position.

Internal Structure

  • Cardiac Walls: Composed of myocardium (striated cardiac muscle).
  • Endocardium: A smooth epithelial layer lining the heart's chambers.
  • Chambers: Four chambers, including two atria and two ventricles.
  • Atria are less muscular than ventricles.
  • Valves: Located between atria and ventricles, and at major blood vessel junctures.
  • Supported by ligaments to ensure unidirectional blood flow.

Blood Flow Dynamics

  • Superior and Inferior Vena Cava: These veins transport deoxygenated blood from the upper and lower parts of the body respectively to the right atrium.
  • Pulmonary Circulation: Blood is sent from the right ventricle to the lungs for oxygenation, then back to the left atrium.
  • Systemic Circulation: Oxygen-rich blood from the left ventricle is pumped through the aorta to the body.

Cardiovascular Diseases

  • Heart Attack (Myocardial Infarction):
  • Coronary arteries are blocked by plaques, leading to cardiac muscle death.
  • Caused by atherosclerosis, potentially manifesting as chest pain or acute blockage.
  • Hypertension:
  • Persistently high blood pressure (≥140/90 mm Hg), increasing risks like strokes and aneurysms.
  • Defined as ≥140/90 mm Hg
  • Results from increased resistance to blood flow within arteries
  • Hypotension:
  • Unusually low blood pressure, leading to dizziness, fainting, and shock.
  • Vital organs are deprived of sufficient blood flow

Preventative and Remedial Measures

  • Lifestyle adjustments (diet, exercise) and medical interventions (stents, surgeries, transplants) are recommended.
  • Valve replacements, bypass surgeries, and pacemakers are medical interventions

Treatment of Heart Diseases

  • Cardiac Cycle: The sequence of events during a heartbeat that pumps blood through the body, maintaining circulation.

Phases of the Cardiac Cycle

  • Atrial Systole:
  • Duration: 0.1 seconds.
  • The SA node generates an electrical impulse, causing the atria to contract.
  • Blood is forced into the ventricles as the tricuspid and bicuspid valves open.
  • Tricuspid valve is on the right side
  • Bicuspid valve is on the left side
  • Ventricular Systole:
  • Duration: 0.3 seconds.
  • The impulse travels from the SA node to the AV node and ventricles, causing them to contract.
  • Blood is pushed into the aorta and pulmonary arteries as the tricuspid and bicuspid valves close.
  • Diastole (General Relaxation):
  • Duration: 0.4 seconds.
  • Both atria and ventricles relax.
  • Semilunar valves at the aorta and pulmonary arteries close.
  • Blood fills the atria from the vena cava and pulmonary veins.
  • Blood fills the atria from the superior and inferior vena cava

Sequence of Blood Flow

  • Deoxygenated blood returns to the right atrium, moves to the right ventricle, and is pumped to the lungs via the pulmonary arteries.
  • Oxygenated blood returns to the left atrium, moves to the left ventricle, and is distributed to the body through the aorta.

Control of Heartbeat

  • The SA node, located in the right atrium, acts as the natural pacemaker of the heart.
  • Factors like temperature, oxygen levels, and emotional states can influence the heartbeat.
  • Physical activities accelerate the heartbeat by increasing CO2 levels and activating stretch receptors in the right atrium.

Exercise Influence on Heartbeat

  • Increased Cellular Respiration:
  • Raises CO2 levels, stimulating receptors in the carotid arteries and aorta.
  • Signals are sent to the heart to increase the rate of contraction.
  • Manages heightened demand for oxygen and nutrients
  • Muscular Activity:
  • Promotes higher blood volume returning to the right atrium, stimulating it to beat faster.
  • Manages the increased blood flow

Cardiovascular Health Management

  • Regular exercise and a balanced diet are essential for managing heart health.
  • Lifestyle adjustments and medical interventions like medication, stents, and surgeries can manage cardiovascular diseases.
  • High blood pressure, heart attacks, and strokes, can be managed or prevented through lifestyle adjustments and medical interventions

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