Podcast
Questions and Answers
What type of ECs provide a barrier to solutes and maintain bloodstream homeostasis?
What type of ECs provide a barrier to solutes and maintain bloodstream homeostasis?
- Quiescent ECs (correct)
- Anti-VEGF ECs
- VEGF-resistant ECs
- Pro-inflammatory ECs
Which mediator acts on post-capillary venules to increase microvascular permeability?
Which mediator acts on post-capillary venules to increase microvascular permeability?
- Epinephrine
- Vascular endothelial growth factor (correct)
- Glucagon
- Insulin
What is the main determinant of microvascular permeability?
What is the main determinant of microvascular permeability?
- Pro-inflammatory mediators
- Barrier properties of the endothelium (correct)
- Anti-VEGF drugs
- Microvascular endothelial cells
Which process involves ECs driving the formation of new blood vessels from existing ones?
Which process involves ECs driving the formation of new blood vessels from existing ones?
Which type of cells regulate vascular barrier function and control inflammation?
Which type of cells regulate vascular barrier function and control inflammation?
What process is characterized by the sprouting of new lymphatic blood vessels?
What process is characterized by the sprouting of new lymphatic blood vessels?
Which system is involved in the regulation of lymphangiogenesis?
Which system is involved in the regulation of lymphangiogenesis?
Which drug would most likely inhibit the formation of new lymphatic vessels?
Which drug would most likely inhibit the formation of new lymphatic vessels?
Which signaling system is important in the process of angiogenesis and vasculogenesis?
Which signaling system is important in the process of angiogenesis and vasculogenesis?
In patients with VEGF resistance, what factor might be a contributing cause?
In patients with VEGF resistance, what factor might be a contributing cause?
How is myosin light chain dephosphorylation achieved?
How is myosin light chain dephosphorylation achieved?
In resistance vessels, what is the direct result of endothelial nitric oxide (NO) production?
In resistance vessels, what is the direct result of endothelial nitric oxide (NO) production?
Which type of cells regulate vascular function and integrity by forming a mono-cellular layer along the lumen of blood vessels?
Which type of cells regulate vascular function and integrity by forming a mono-cellular layer along the lumen of blood vessels?
What is involved in the pathogenesis of arteriosclerosis according to the text?
What is involved in the pathogenesis of arteriosclerosis according to the text?
Which process is Rho/ROCK signaling involved in according to the text?
Which process is Rho/ROCK signaling involved in according to the text?
What is the main purpose of using anti-VEGF and anti-VEGFR drugs in cancer treatment?
What is the main purpose of using anti-VEGF and anti-VEGFR drugs in cancer treatment?
What is a potential application of VEGF in medicine?
What is a potential application of VEGF in medicine?
What is responsible for impaired neovessel formation in ischemic disease?
What is responsible for impaired neovessel formation in ischemic disease?
What is a role of Notch signaling in VEGF resistance?
What is a role of Notch signaling in VEGF resistance?
What is the limitation of using VEGF gene therapy for critical limb ischemia?
What is the limitation of using VEGF gene therapy for critical limb ischemia?
