Angina

Which neurotransmitter is released by sympathetic innervation in the coronary vessels?

Which receptor activation in the large coronary vessels results in vasoconstriction?

Which receptor activation in the smaller coronary vessels induces vasodilation?

Which neurotransmitter is released by parasympathetic nerves in the heart?

Which receptor activation slows heart rate and automaticity?

Which type of angina is brought on by exertion or excitement?

Which of the following is a common side effect of HMG-CoA reductase inhibitors?

Which of the following is the rate-limiting enzyme in cholesterol synthesis?

Which type of dyslipidaemia is characterized by high levels of cholesterol and LDL in the blood?

Which of the following is contraindicated in people with cardiogenic shock, left ventricular failure, and hypotension?

Which lipoprotein absorbs cholesterol from broken down cells and transfers them to LDLs or VLDLs?

Which lipid-lowering drug class is commonly used as an adjunct to low-fat diets to decrease plasma LDL cholesterol?

Which type of angina is characterized by vasospasm of coronary vessels and possible atherosclerosis?

Which of the following is NOT a mechanism of nitrate relief of symptoms of angina?

Which of the following is a possible adverse effect of nitrates?

Which class of drugs exerts a negative chronotropic effect and slows the heart rate, thereby decreasing oxygen consumption?

Which of the following is NOT an adverse effect of beta-adrenoceptor antagonists?

Which class of drugs is useful in unstable angina and angina at rest, and acts as calcium entry blockers?

Which of the following is true about the drugs used to treat Angina?

Which of the following is true about the drugs used to treat dyslipidaemia?

Which of the following is true about the drugs used to treat hypertension?

Which of the following is true about diuretics?

Which of the following is true about the drugs used to treat Heart Failure?

Which of the following is true about the drugs used to treat excess blood clotting and platelet activity?

Which one of the following drugs is known to increase the metabolism of endogenous cholesterol into bile acids in the liver?

Which one of the following drugs is indicated for hypercholesterolemia when treatment with Statin alone is inadequate or not tolerated?

Which one of the following drugs binds to protoprotein convertase subtilisin/kexin type 9 (PCSK9) to inhibit its activity?

Which one of the following drugs stimulates lipoprotein lipase, increasing the hydrolysis of triglyceride in chylomicron and VLDL particles?

Which one of the following drugs decreases hepatic lipoprotein synthesis and inhibits hepatic triglyceride production and VLDL secretion?

Which one of the following dietary components has been demonstrated to reduce the absorption of cholesterol?

Unstable Angina is characterized by pain at rest.

Nitrates induce peripheral vasoconstriction.

The liberation of NO from organic nitrates requires an enzymic reaction that involves tissue SH groups.

Long-acting nitrates are taken once daily for prophylaxis.

Beta-adrenoceptor antagonists are useful in the treatment of vasospastic angina.

Calcium antagonists have no effect on intracellular actions.

True or false: The myocardium accounts for 4% of the cardiac output.

True or false: Diastole is shortened during tachycardia, reducing the time available for myocardial perfusion.

True or false: A decrease in arterial PO2 and pH results in the release of vasodilator compounds.

True or false: Adenosine is a vasoconstrictor.

True or false: HMG-CoA reductase inhibitors decrease hepatic lipoprotein synthesis.

True or false: PCSK9 inhibitors inhibit the activity of protoprotein convertase subtilisin/kexin type 9.

True or false: Stimulation of α1-adrenoceptors in large coronary vessels results in vasoconstriction?

True or false: Stimulation of β2-adrenoceptors in smaller coronary vessels induces vasodilation?

True or false: Noradrenaline increases heart rate and force of contraction?

True or false: Stimulation of β1-adrenoceptors increases Ca2+ sensitivity of contractile machinery?

True or false: Parasympathetic nerves release acetylcholine, which slows heart rate and automaticity?

True or false: Angina occurs when the oxygen supply to the myocardium is insufficient for its needs?

True or false: Bile acid resins prevent the reabsorption and enterohepatic circulation of bile acids in the liver?

True or false: Ezetimibe inhibits the absorption of fat soluble vitamins and triglycerides from the gastrointestinal tract?

True or false: PCSK9 inhibitors increase LDL clearance from the blood?

True or false: Fibrates decrease plasma LDL levels by 10%?

True or false: Nicotinic acid decreases hepatic triglyceride production and VLDL secretion?

True or false: Fish oils decrease the production of VLDL triglycerides but may increase cholesterol levels?

True or false: Potassium channel activators are contraindicated in people with left ventricular failure?

True or false: Chylomicrons transport cholesterol and triglycerides from the liver to tissues?

True or false: Type IIa dyslipidaemia is characterized by high levels of VLDL and LDL in the blood?

True or false: HMG-CoA reductase inhibitors inhibit cholesterol production by converting HMG-CoA to mevalonic acid?

True or false: Statins can improve endothelial function and reduce vascular inflammation?

True or false: Rhabdomyolysis is a rare side effect of HMG-CoA reductase inhibitors?