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Questions and Answers
What is the primary effect of anesthetics on neuronal activity?
What is the primary effect of anesthetics on neuronal activity?
- Action potential propagation
- Synaptic transmission (correct)
- Neurotransmitter release
- Dendritic spine formation
Which type of receptors are anesthetics thought to block?
Which type of receptors are anesthetics thought to block?
- TREK potassium channels
- GABA-A receptors
- Glutamatergic receptors (correct)
- Muscarinic receptors
What is the effect of anesthetics on inhibitory synaptic transmission?
What is the effect of anesthetics on inhibitory synaptic transmission?
- They block inhibitory receptors
- They have no effect on inhibitory receptors
- They enhance the function of inhibitory receptors (correct)
- They reduce the release of inhibitory neurotransmitters
Which of the following neurotransmitters is associated with excitatory synaptic transmission?
Which of the following neurotransmitters is associated with excitatory synaptic transmission?
What is the effect of anesthetics on cholinergic receptors?
What is the effect of anesthetics on cholinergic receptors?
What is the primary site of action for anesthetics?
What is the primary site of action for anesthetics?
What type of receptors are enhanced by anesthetics during inhibitory synaptic transmission?
What type of receptors are enhanced by anesthetics during inhibitory synaptic transmission?
Which of the following is NOT an excitatory receptor blocked by anesthetics?
Which of the following is NOT an excitatory receptor blocked by anesthetics?
What is the effect of anesthetics on TREK potassium channels?
What is the effect of anesthetics on TREK potassium channels?
What is the net effect of anesthetics on synaptic transmission?
What is the net effect of anesthetics on synaptic transmission?
What is the net result of anesthetic action on synaptic transmission?
What is the net result of anesthetic action on synaptic transmission?
Which receptor type is anesthetic action thought to enhance?
Which receptor type is anesthetic action thought to enhance?
What is the primary neurotransmitter associated with inhibitory synaptic transmission?
What is the primary neurotransmitter associated with inhibitory synaptic transmission?
Anesthetics are thought to block which type of receptors during excitatory synaptic transmission?
Anesthetics are thought to block which type of receptors during excitatory synaptic transmission?
What are anesthetics thought to affect during inhibitory synaptic transmission?
What are anesthetics thought to affect during inhibitory synaptic transmission?
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Study Notes
Anaesthetic Effects on Synaptic Transmission
- Anaesthetics predominantly affect synaptic transmission, rather than action potential propagation.
Excitatory Synaptic Transmission
- Anaesthetics block excitatory receptors, including:
- Glutamatergic receptors
- Cholinergic receptors
- Serotonergic (5HT) receptors
Inhibitory Synaptic Transmission
- Anaesthetics generally enhance the function of inhibitory synaptic receptors, including:
- GABA-A receptors
- TREK potassium channels
Anaesthetic Effects on Synaptic Transmission
- Anaesthetics predominantly affect synaptic transmission, rather than action potential propagation.
Excitatory Synaptic Transmission
- Anaesthetics block excitatory receptors, including:
- Glutamatergic receptors
- Cholinergic receptors
- Serotonergic (5HT) receptors
Inhibitory Synaptic Transmission
- Anaesthetics generally enhance the function of inhibitory synaptic receptors, including:
- GABA-A receptors
- TREK potassium channels
Anaesthetic Effects on Synaptic Transmission
- Anaesthetics predominantly affect synaptic transmission, rather than action potential propagation.
Excitatory Synaptic Transmission
- Anaesthetics block excitatory receptors, including:
- Glutamatergic receptors
- Cholinergic receptors
- Serotonergic (5HT) receptors
Inhibitory Synaptic Transmission
- Anaesthetics generally enhance the function of inhibitory synaptic receptors, including:
- GABA-A receptors
- TREK potassium channels
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