Anesthetics' Effects on Synaptic Transmission
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Questions and Answers

What is the primary effect of anesthetics on neuronal activity?

  • Action potential propagation
  • Synaptic transmission (correct)
  • Neurotransmitter release
  • Dendritic spine formation
  • Which type of receptors are anesthetics thought to block?

  • TREK potassium channels
  • GABA-A receptors
  • Glutamatergic receptors (correct)
  • Muscarinic receptors
  • What is the effect of anesthetics on inhibitory synaptic transmission?

  • They block inhibitory receptors
  • They have no effect on inhibitory receptors
  • They enhance the function of inhibitory receptors (correct)
  • They reduce the release of inhibitory neurotransmitters
  • Which of the following neurotransmitters is associated with excitatory synaptic transmission?

    <p>Glutamate</p> Signup and view all the answers

    What is the effect of anesthetics on cholinergic receptors?

    <p>They block cholinergic receptors</p> Signup and view all the answers

    What is the primary site of action for anesthetics?

    <p>Synapses</p> Signup and view all the answers

    What type of receptors are enhanced by anesthetics during inhibitory synaptic transmission?

    <p>GABA-A</p> Signup and view all the answers

    Which of the following is NOT an excitatory receptor blocked by anesthetics?

    <p>GABA-A</p> Signup and view all the answers

    What is the effect of anesthetics on TREK potassium channels?

    <p>Enhancement</p> Signup and view all the answers

    What is the net effect of anesthetics on synaptic transmission?

    <p>Enhance inhibitory transmission</p> Signup and view all the answers

    What is the net result of anesthetic action on synaptic transmission?

    <p>Depressed overall transmission</p> Signup and view all the answers

    Which receptor type is anesthetic action thought to enhance?

    <p>GABA-A receptors</p> Signup and view all the answers

    What is the primary neurotransmitter associated with inhibitory synaptic transmission?

    <p>GABA</p> Signup and view all the answers

    Anesthetics are thought to block which type of receptors during excitatory synaptic transmission?

    <p>Serotonergic receptors</p> Signup and view all the answers

    What are anesthetics thought to affect during inhibitory synaptic transmission?

    <p>GABA-A receptors</p> Signup and view all the answers

    Study Notes

    Anaesthetic Effects on Synaptic Transmission

    • Anaesthetics predominantly affect synaptic transmission, rather than action potential propagation.

    Excitatory Synaptic Transmission

    • Anaesthetics block excitatory receptors, including:
      • Glutamatergic receptors
      • Cholinergic receptors
      • Serotonergic (5HT) receptors

    Inhibitory Synaptic Transmission

    • Anaesthetics generally enhance the function of inhibitory synaptic receptors, including:
      • GABA-A receptors
      • TREK potassium channels

    Anaesthetic Effects on Synaptic Transmission

    • Anaesthetics predominantly affect synaptic transmission, rather than action potential propagation.

    Excitatory Synaptic Transmission

    • Anaesthetics block excitatory receptors, including:
      • Glutamatergic receptors
      • Cholinergic receptors
      • Serotonergic (5HT) receptors

    Inhibitory Synaptic Transmission

    • Anaesthetics generally enhance the function of inhibitory synaptic receptors, including:
      • GABA-A receptors
      • TREK potassium channels

    Anaesthetic Effects on Synaptic Transmission

    • Anaesthetics predominantly affect synaptic transmission, rather than action potential propagation.

    Excitatory Synaptic Transmission

    • Anaesthetics block excitatory receptors, including:
      • Glutamatergic receptors
      • Cholinergic receptors
      • Serotonergic (5HT) receptors

    Inhibitory Synaptic Transmission

    • Anaesthetics generally enhance the function of inhibitory synaptic receptors, including:
      • GABA-A receptors
      • TREK potassium channels

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    Description

    This quiz explores the impact of anesthetics on synaptic transmission, focusing on excitatory and inhibitory receptors. It covers the blocking of receptors like Glutamatergic, Cholinergic, and Serotonergic, and the enhancement of GABA-A receptors and TREK potassium channels.

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