Podcast
Questions and Answers
What is the role of FA in understanding the uptake and distribution of inhaled anesthetics?
What is the role of FA in understanding the uptake and distribution of inhaled anesthetics?
- FA describes the partial pressure of anesthetic in the gas phase
- FA measures the blood concentration of inhaled anesthetic
- FA reflects the concentration of inhaled anesthetic in the lungs
- FA is an alternative to direct measurement of brain concentration of inhaled anesthetic (correct)
How can the rate of rise of FA/FI be increased?
How can the rate of rise of FA/FI be increased?
- By maintaining constant alveolar blood flow
- By decreasing the time constant (correct)
- By increasing the volume/flow ratio
- By increasing the time constant
What does the second gas effect describe?
What does the second gas effect describe?
- The rapid washout of more-soluble inhaled anesthetics
- The rapid uptake of gases from blood to lungs
- The delayed effect of certain anesthetics on brain activity
- The acceleration of FA rate due to large volume uptake of a companion gas (correct)
What factor has the greatest effect on the rate of rise of FA/FI?
What factor has the greatest effect on the rate of rise of FA/FI?
In first-order kinetics, how can the time constant be defined?
In first-order kinetics, how can the time constant be defined?
What is the driving force for movement of anesthetic agent into the blood?
What is the driving force for movement of anesthetic agent into the blood?
How does increased alveolar ventilation affect the rate of rise of FA/FI?
How does increased alveolar ventilation affect the rate of rise of FA/FI?
How does high fresh gas flows influence the rate of rise of FA/FI?
How does high fresh gas flows influence the rate of rise of FA/FI?
What happens to the rate of rise of FA/FI with decreased FRC (functional residual capacity)?
What happens to the rate of rise of FA/FI with decreased FRC (functional residual capacity)?
What does the concentration of anesthetic in a tissue depend on?
What does the concentration of anesthetic in a tissue depend on?
What is the relationship between volume of gas and mass in the gas phase according to the Ideal Gas Law?
What is the relationship between volume of gas and mass in the gas phase according to the Ideal Gas Law?
What factors affect the transfer of anesthetic from the machine to the alveoli?
What factors affect the transfer of anesthetic from the machine to the alveoli?
In which tissue group does the vessel-rich group consist of, according to Barash?
In which tissue group does the vessel-rich group consist of, according to Barash?
What happens to the temperature when liquid changes into vapor in an anesthetic vaporizer?
What happens to the temperature when liquid changes into vapor in an anesthetic vaporizer?
What affects the transfer of anesthetic from blood to tissues?
What affects the transfer of anesthetic from blood to tissues?
What is the purpose of a variable bypass in an anesthetic vaporizer?
What is the purpose of a variable bypass in an anesthetic vaporizer?
Why is it important for anesthetic vaporizers to be pressure compensated?
Why is it important for anesthetic vaporizers to be pressure compensated?
What is the main function of a flow-over anesthetic vaporizer?
What is the main function of a flow-over anesthetic vaporizer?
What does Dalton's Law describe about gases in a mixture?
What does Dalton's Law describe about gases in a mixture?
What happens if a vaporizer is filled with an agent having a higher vapor pressure than it is designed for?
What happens if a vaporizer is filled with an agent having a higher vapor pressure than it is designed for?
What does FA0 represent in the context of anesthetics?
What does FA0 represent in the context of anesthetics?
During exhalation and recovery, what is the primary reason for the rapid fall in partial pressure of the anesthetic agent in the central nervous system (Pcns)?
During exhalation and recovery, what is the primary reason for the rapid fall in partial pressure of the anesthetic agent in the central nervous system (Pcns)?
What effect does discontinuing nitrous oxide have on alveolar partial pressures?
What effect does discontinuing nitrous oxide have on alveolar partial pressures?
What should be used when discontinuing nitrous oxide at the end of an anesthetic?
What should be used when discontinuing nitrous oxide at the end of an anesthetic?
What is the driving force for the movement of anesthetic agent into the blood?
What is the driving force for the movement of anesthetic agent into the blood?
How does increased cardiac output affect the rate of rise of FA/FI?
How does increased cardiac output affect the rate of rise of FA/FI?
Which factor speeds up the rate of rise of FA/FI?
Which factor speeds up the rate of rise of FA/FI?
Which factor decreases the volume in the volume/flow equation, leading to a shorter time constant?
Which factor decreases the volume in the volume/flow equation, leading to a shorter time constant?
How does high fresh gas flows influence the rate of rise of FA/FI?
How does high fresh gas flows influence the rate of rise of FA/FI?
What happens to FA/FI when the alveolar ventilation is increased?
What happens to FA/FI when the alveolar ventilation is increased?
How does low blood solubility affect the rate of rise of FA/FI?
How does low blood solubility affect the rate of rise of FA/FI?
Decreasing cardiac output will decrease the rate of rise of FA.
Decreasing cardiac output will decrease the rate of rise of FA.
Metabolism plays a significant role in altering the pharmacokinetics of inhalational anesthetics.
Metabolism plays a significant role in altering the pharmacokinetics of inhalational anesthetics.
Right-to-left shunt accelerates induction due to faster alveolar FA rise.
Right-to-left shunt accelerates induction due to faster alveolar FA rise.
The pharmacokinetics of inhalational agents can be best described by a 2 compartment model.
The pharmacokinetics of inhalational agents can be best described by a 2 compartment model.