Questions and Answers
Which of the following is a cause of Iron Deficiency Anemia (IDA) in adult men and postmenopausal women?
GI bleeds from peptic ulcer
Which nutrient deficiency is linked to defective RBC production or inadequate RBC production?
Folic acid
What is a common cause of IDA in children?
Diet consisting heavily of cow's milk
What is a typical diagnostic feature of Iron Deficiency Anemia (IDA)?
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Which of the following is NOT a manifestation of Iron Deficiency Anemia (IDA)?
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Which of the following statements is true about the destruction (hemolysis) of RBCs?
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Which factor does NOT contribute to anemia due to hemolysis of red blood cells?
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Which condition specifically contributes to iron deficiency anemia (IDA) among women of childbearing age?
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Which manifestation of anemia involves unusual cravings for non-nutritional substances?
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In the context of childhood iron deficiency anemia, which dietary factor is typically implicated?
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What is a significant reason for the high iron requirement in infants aged 3-24 months?
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Which of the following is NOT a cause of chronic blood loss leading to IDA in postmenopausal women?
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Study Notes
Anemias of Deficient Red Cell Production
Iron Deficiency Anemia (IDA)
- IDA is caused by loss of RBCs from bleeding, leading to iron loss and deficiency (e.g., GI bleeds, menstrual cycle disorders)
- IDA can also be caused by defective RBC production or inadequate RBC production from bone marrow failure, leading to decreased production of erythrocytes and deficiency in nutrients for production (folic acid and cobalamin)
Causes of IDA in Adults
- Chronic blood loss
- GI bleeds in men and postmenopausal women (e.g., peptic ulcer, vascular lesions, intestinal polyps, hemorrhoids, or cancer)
- Increased iron demand in childbearing age women due to menstrual cycle
Causes of IDA in Children
- Increased iron demand due to child growth
- Highest iron requirements in infancy (3-24 months)
- Deficiency often caused by low iron levels at birth due to maternal deficiency and diet consisting of cow's milk
Anemia Manifestation
- Fatigue
- Irritability
- PICA (cravings for non-nutritive substances)
- Dyspnea
- Tachycardia
- Angina
- Palpitations
Diagnosis
- Decreased MCHC (mean corpuscular hemoglobin concentration)
- Decreased MCV (mean corpuscular volume)
Anemias of Deficient Red Cell Production
Iron Deficiency Anemia (IDA)
- IDA is caused by loss of RBCs from bleeding, leading to iron loss and deficiency (e.g., GI bleeds, menstrual cycle disorders)
- IDA can also be caused by defective RBC production or inadequate RBC production from bone marrow failure, leading to decreased production of erythrocytes and deficiency in nutrients for production (folic acid and cobalamin)
Causes of IDA in Adults
- Chronic blood loss
- GI bleeds in men and postmenopausal women (e.g., peptic ulcer, vascular lesions, intestinal polyps, hemorrhoids, or cancer)
- Increased iron demand in childbearing age women due to menstrual cycle
Causes of IDA in Children
- Increased iron demand due to child growth
- Highest iron requirements in infancy (3-24 months)
- Deficiency often caused by low iron levels at birth due to maternal deficiency and diet consisting of cow's milk
Anemia Manifestation
- Fatigue
- Irritability
- PICA (cravings for non-nutritive substances)
- Dyspnea
- Tachycardia
- Angina
- Palpitations
Diagnosis
- Decreased MCHC (mean corpuscular hemoglobin concentration)
- Decreased MCV (mean corpuscular volume)
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Description
Compare the causes of iron deficiency anemia in adults and children, and identify the most common causes in each group. Learn about the role of bleeding, hemolysis, and erythropoiesis in anemia.
