Anemia and Hemoglobin Quiz
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Questions and Answers

What do Julian's results indicate about the permeability of the dialysis tubing?

  • The tubing is impermeable to both iodine and starch.
  • The tubing is permeable to starch but not to iodine.
  • The tubing is permeable to both iodine and starch.
  • The tubing is permeable to iodine but not to starch. (correct)

Which glycoprotein in raw egg whites can impair biotin absorption, leading to deficiency?

  • Ovolactin
  • Lysozyme
  • Avidin (correct)
  • Ovotransferrin

What is the ratio of HCO3- to H2CO3 in the bicarbonate/carbonic acid buffer system?

  • 25:1
  • 20:1 (correct)
  • 10:1
  • 15:1

What substance's concentration increases in the blood due to thiamine deficiency?

<p>Lactate (A)</p> Signup and view all the answers

What characteristic of cyclic AMP (cAMP) enhances its function as a second messenger?

<p>It can activate protein kinases A. (C)</p> Signup and view all the answers

In a premature infant, which immunoglobulin is most likely to be deficient?

<p>Immunoglobulin A (C)</p> Signup and view all the answers

Which two sugars are classified as anomers?

<p>α-D-glucose and β-D-glucose (B)</p> Signup and view all the answers

What directly affects the reaction catalyzed by enzymes requiring vitamin B5?

<p>Coenzyme A formation (C)</p> Signup and view all the answers

What is the primary vitamin deficiency indicated by the presence of hypersegmented neutrophils in a vegetarian patient with anemia?

<p>Vitamin B12 deficiency (A)</p> Signup and view all the answers

Which glycoprotein found in raw egg white interferes with the absorption of biotin?

<p>Avidin (A)</p> Signup and view all the answers

During dialysis testing with starch solution, what does a blue-black color indicate about the dialysis tubing's permeability?

<p>Tubing is permeable to iodine but not to starch (A)</p> Signup and view all the answers

In terms of membrane potential, what causes a slight excess of negative charge inside the cell membrane during resting conditions?

<p>Unequal distribution of K+ ions (C)</p> Signup and view all the answers

What enzyme co-factor is formed from Vitamin B6 and is essential for amino acid metabolism?

<p>Pyridoxal phosphate (PLP) (D)</p> Signup and view all the answers

In a male with hemophilia whose wife is not a carrier, what is the probability of them having a daughter who is a carrier of the hemophilia trait?

<p>0% (C)</p> Signup and view all the answers

What is the effect of decreasing the diameter of a tube on capillary action?

<p>Increases capillary action (A)</p> Signup and view all the answers

Which of the following glycosaminoglycans does not contain uronic acid?

<p>Keratan sulfate (D)</p> Signup and view all the answers

What does Julian's experiment with dialysis tubing demonstrate about the permeability of the tubing?

<p>The dialysis tubing is permeable to iodine but not to starch (A)</p> Signup and view all the answers

Which glycoprotein found in raw egg whites can affect biotin absorption in the small intestine?

<p>Avidin (A)</p> Signup and view all the answers

In the bicarbonate/carbonic acid buffer system, what is the ideal ratio of HCO3- to H2CO3 for maintaining pH in the extracellular fluid?

<p>20:1 (A)</p> Signup and view all the answers

What is the result of thiamine deficiency in individuals consuming a rice staple diet?

<p>Increased concentrations of lactate (C)</p> Signup and view all the answers

Which characteristic of cyclic AMP (cAMP) is most crucial for its role as a second messenger?

<p>It can activate protein kinases A (D)</p> Signup and view all the answers

Which immunoglobulin is likely deficient in a 3-month-old infant who was born prematurely and has a history of urinary tract infections?

<p>Immunoglobulin A (B)</p> Signup and view all the answers

What is the ability of niacin to participate in redox reactions dependent on?

<p>Its ability to convert to NAD and NADP forms (B)</p> Signup and view all the answers

A deficiency in vitamin B5 (pantothenic acid) would directly affect the reaction catalyzed by which enzyme?

<p>Acetyl-CoA synthetase (A)</p> Signup and view all the answers

Flashcards

Dialysis Tubing Permeability

Dialysis tubing allows iodine to pass through, but starch cannot.

Capillary Action & Tube Diameter

Capillary action is stronger in smaller tubes.

Biotin Deficiency & Raw Eggs

Avidin, a protein in raw egg whites, binds biotin, preventing its absorption.

Buffer Ratio (HCO3-/H2CO3)

The ideal ratio in the bicarbonate/carbonic acid buffer system is 20:1.

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Thiamine Deficiency & Lactate

Low thiamine leads to higher blood lactate levels.

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Anomers

Sugars with only a single differing configuration.

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cAMP & Protein Kinases

cAMP's ability to activate protein kinases A is key to its signaling role.

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Immunoglobulin Deficiency in Infants

Premature infants often have Immunoglobulin A deficiency.

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Sugars with Single Configuration Difference

Two sugars are called anomers if they differ only in the configuration around one specific carbon atom.

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Immunoglobulin A (IgA) Deficiency

Premature infants often have a deficiency in Immunoglobulin A (IgA), which provides immunity in the respiratory and digestive systems.

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Pyruvate Dehydrogenase

An enzyme complex that catalyzes the conversion of pyruvate to acetyl-CoA. This is a key step in cellular respiration, linking glycolysis to the Krebs cycle.

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Keratan Sulfate

A glycosaminoglycan (GAG) that does not contain uronic acid. It is found in cartilage, bone, and cornea.

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Vitamin B12 Deficiency Anemia

A type of anemia caused by a lack of vitamin B12. Symptoms include fatigue, weakness, pallor, and hypersegmented neutrophils.

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Tryptophan & Vitamin B6 Deficiency

A urinary xanthurenic acid test is used to diagnose vitamin B6 deficiency. A dose of tryptophan is given, and increased xanthurenic acid excretion indicates deficiency.

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Ferritin

An intracellular iron storage protein that can bind to more than 100 iron atoms. It helps regulate iron levels in the body.

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Hemophilia Carrier Probability

If a father with hemophilia and a mother without the gene have a daughter, the probability of the daughter being a carrier is 0%.

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Resting Membrane Potential & K+

During resting conditions, the inside of a cell is slightly negative due to an unequal distribution of potassium ions (K+). More K+ ions leak out than enter the cell.

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Study Notes

Anemia

  • Folic acid deficiency anemia is a common preventable cause of anemia in China
  • Loss of cell substance is called atrophy
  • Hyperplasia is an increase in cell size
  • Active hyperemia is a vascular reaction
  • Passive congestion is a vascular reaction
  • Platelets aggregation is a mechanism
  • Warfarin inhibits factors II, VII, IX, and X in blood clotting
  • Pregnant women are most affected by anemia globally
  • Folic acid supplements prevent neural tube defects in newborns during pregnancy
  • Three-year-old child skin injury from candle is called an ulceration
  • Epidemiological triad includes agent, vector, environment

Hemoglobin

  • Hemoglobin is a protein that transports oxygen in the blood
  • Hemoglobin's structure, specifically the iron-containing heme part, is crucial for oxygen transport
  • Hemoglobin contains two identical alpha and two identical beta chains within its structure.

Vitamins

  • Vitamin B5 deficiency affects pyruvate dehydrogenase.
  • Vitamin B5 is a water-soluble vitamin

Wound Healing

  • Organization is a process after wound healing contends, but the injury site may have a prominent raised nodular scar over time
  • Dehiscence is when wound healing fails to correctly close
  • Keloid is an overgrowth of scar tissue which causes a prominent raised scar
  • Organization and dehiscence can occur after injury

Communication

  • Attentive listening, confidentiality, knowledge of the patient, and empathy are essential components for effective communication between a doctor and a patient
  • Group communication is a type of communication occurring in a physiology lecture setting.

Allergies

  • Histamine is a substance that likely causes nasal congestion and secretions in a cat dander allergy.

Blood

  • Antibodies are a major part of the plasma proteins
  • Antibodies constitute approximately 50% of plasma proteins.
  • Antibodies are distributed unequally between plasma and serum.
  • Antibodies contain at least two antigen binding sites.

Blood Components

  • Hemoglobin content and hematocrit of a young man are 17 Gm/dl and 50%, respectively. MCHC is 32% (g/dl).

Genetic Conditions

  • Hemophilia is a genetic disorder.
  • If a male with hemophilia has a baby girl, there is a 75% chance that she is a hemophilia carrier.

Other

  • Dialysis tubing is permeable to iodine but not to starch.
  • Bicarbonate/carbonic acid buffer ratio is 20:1.
  • Avidin is a protein that can affect biotin absorption in the small intestine when consumed in raw egg whites.

Other

  • Blood-thymus barrier is formed from the presence of occluding junctions between adjacent type 1 epithelioreticular cells.

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Description

Test your knowledge on the important aspects of anemia, hemoglobin structure, and the role of vitamins in health. This quiz covers topics such as folic acid deficiency, hemoglobin's transport function, and essential vitamins. Perfect for students interested in medical science or health-related fields.

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