Anatomy & Physiology: Acid-Base Balance Regulation Quiz
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Questions and Answers

In which mode are dialyzers typically operated today?

  • Diffusion mode
  • Countercurrent flow mode (correct)
  • Constant concentration gradient mode
  • Cocurrent flow mode
  • What is the impact of cocurrent flow mode on the clearance of smaller molecules?

  • Decreases clearance by 10% (correct)
  • Increases clearance by 10%
  • Maintains constant clearance
  • Clearance remains unchanged
  • What is the Sieving coefficient for larger molecules in exemplary dialyzers?

  • 59%
  • Constant
  • Not mentioned in the text
  • 10% (correct)
  • What does the sieving coefficient (S) represent?

    <p>The ratio of concentration in filtrate to concentration in plasma</p> Signup and view all the answers

    What is the fractional excretion (FE) defined as?

    <p>The percentage of a substance's matter flow in the final urine compared to the matter flow in the primary urine</p> Signup and view all the answers

    What does renal blood flow (RBF) represent?

    <p>Blood flow through the kidneys</p> Signup and view all the answers

    What is the primary function of the cells in the proximal tubule in relation to the acid-base balance?

    <p>Reabsorbing bicarbonate (HCO3-) and excreting H+ protons</p> Signup and view all the answers

    How does the kidney regulate the balance in case of alkalosis?

    <p>By decreasing the reabsorption of bicarbonate and increasing the excretion of bicarbonate</p> Signup and view all the answers

    What is the role of the lungs in regulating the acid-base balance?

    <p>Excreting CO2 generated by cells</p> Signup and view all the answers

    What is the primary function of renal blood flow (RBF) in relation to kidney parameters?

    <p>Maintaining glomerular filtration rate (GFR)</p> Signup and view all the answers

    Study Notes

    Dialyzer Operation

    • Dialyzers are typically operated in countercurrent flow mode today.

    Clearance of Small Molecules

    • Cocurrent flow mode decreases the clearance of smaller molecules.

    Sieving Coefficient

    • The sieving coefficient (S) represents the ability of a dialyzer to remove molecules of a specific size.
    • For larger molecules, the sieving coefficient (S) is typically lower in exemplary dialyzers.

    Renal Function

    • Renal blood flow (RBF) represents the amount of blood that flows through the kidneys.
    • Primary function of RBF is to regulate kidney parameters such as filtration rate and waste removal.

    Acid-Base Balance

    • Cells in the proximal tubule play a crucial role in maintaining acid-base balance by reabsorbing bicarbonate and eliminating hydrogen ions.
    • In cases of alkalosis, the kidney regulates the balance by increasing hydrogen ion excretion and decreasing bicarbonate reabsorption.

    Respiratory Regulation

    • Lungs play a vital role in regulating the acid-base balance by removing carbon dioxide through exhalation, which helps to reduce hydrogen ion concentration in the blood.

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    Description

    Test your knowledge of the regulatory effect on the acid-base balance, focusing on the role of the lungs and kidneys in managing CO2 and bicarbonate levels. Understand the processes of CO2 generation, excretion by the lungs, and H+ excretion and HCO3- reabsorption by the kidneys.

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