Anatomy of the Large Intestine
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Questions and Answers

What is the function of the collagen table in the lamina propria of the large intestine?

  • Regulation of absorption of water and electrolytes from ECF to ICF (correct)
  • Production of digestive enzymes
  • Regulation of gut motility
  • Modulation of immune response
  • What is the name of the region between the teniae coli that exhibits sacculations in the large intestine?

  • Haustra (correct)
  • Villi
  • Crypts of Lieberkuhn
  • Plicae
  • What is the name of the small fatty projection on the serosa outer surface of the large intestine?

  • Teniae coli
  • Plicae
  • Haustra
  • Omenta appendices (correct)
  • What is the approximate turnover time of mucosal epithelial cells in the large intestine?

    <p>4-6 days</p> Signup and view all the answers

    What is the name of the lymphatic nodules that are abundant in the large intestine and extend into the sub-mucosa?

    <p>GALT</p> Signup and view all the answers

    What is the name of the thickened equally spaced parts of the outer longitudinal layer in the muscularis externa of the large intestine?

    <p>Teniae coli</p> Signup and view all the answers

    What is the name of the glands present in the mucosa of the large intestine?

    <p>Crypts of Lieberkuhn</p> Signup and view all the answers

    What is the region of the large intestine where teniae coli are absent?

    <p>All of the above</p> Signup and view all the answers

    What is the characteristic of the solitary lymphatic follicles in the small intestine?

    <p>They are 1 to 2 mm in diameter and form circular or oval patches</p> Signup and view all the answers

    What is the function of the intestinal glands or crypts of Lieberkuhn in the small intestine?

    <p>To secrete digestive enzymes and mucus</p> Signup and view all the answers

    Which of the following arteries supplies the jejunum and ileum?

    <p>Superior mesenteric artery</p> Signup and view all the answers

    What is the characteristic of the villi and microvilli in the small intestine?

    <p>They increase the surface area of absorption</p> Signup and view all the answers

    What is the function of the duodenal glands or Brunner's glands in the small intestine?

    <p>To secrete mucus</p> Signup and view all the answers

    What is the characteristic of the nerve supply of the small intestine?

    <p>It is both sympathetic and parasympathetic</p> Signup and view all the answers

    What is the location of the myenteric plexus of Auerbach in the small intestine?

    <p>Between the circular and longitudinal muscle coats</p> Signup and view all the answers

    What is the characteristic of the aggregated lymphatic follicles or Peyer's patches in the small intestine?

    <p>They are largest and most numerous in the ileum, and are small, circular and fewer in the distal jejunum</p> Signup and view all the answers

    What is the primary function of the Weii Developed Pericryptal Fibroblast Sheath in the large intestine?

    <p>To divide and differentiate into macrophages for immune response</p> Signup and view all the answers

    Which layer of the large intestine is characterized by the absence of lymphatic vessels?

    <p>Lamina propria</p> Signup and view all the answers

    What is the unique feature of the muscularis externa in the large intestine?

    <p>It has two layers, inner circular and outer longitudinal</p> Signup and view all the answers

    What is the function of the Teniae coli in the large intestine?

    <p>To create the sac-like structures called haustra</p> Signup and view all the answers

    What is the characteristic of the mucosa in the rectum?

    <p>It has straight tubular intestinal glands with many Goblet cells</p> Signup and view all the answers

    What is the unique feature of the appendix?

    <p>It has a longitudinal layer of smooth muscle only</p> Signup and view all the answers

    Which layer of the large intestine is absent where the intestine is attached to adjoining structures?

    <p>Serosal</p> Signup and view all the answers

    What is the reason for the delay in the spread of cancers in the large intestine?

    <p>The absence of lymphatic vessels</p> Signup and view all the answers

    Study Notes

    Large Intestine

    • Consists of Cecum, Colon, Rectum, and Anal canal
    • Has 4-layer characteristics of the alimentary canal with adaptations and distinctive features based on functional requirements
    • Gross anatomy:
      • Identified by the presence of teniae coli (3 thickened equally spaced parts of the outer longitudinal layer in the muscularis externa)
      • Absent in the rectum, appendix, and anal canal
      • Haustra: Sacculations on the external surface of the cecum and colon
      • Omenta appendices: Small fatty projections on the serosa outer surface

    Histology

    • Mucosal layer:
      • Made up of Columnar epithelium
      • Contains numerous straight tubular intestine glands (crypts of Lieberkuhn)
      • Other cell types: enterocytes, Goblet cells, enteroendocrine cells, and M cells
      • Plicae, villi, microvilli, and glycocalyx are less prominent compared to small GI
    • Lamina propria:
      • Special features: Collagen table (regulates absorption of water and electrolytes from ECF to ICF)
      • Well-developed GALT (large lymphatic nodules abundant in the large bowel and extends into the sub-mucosa)
      • Well-developed Pericryptal Fibroblast Sheath (a group of fibroblasts that divide beneath the glands and migrate towards the lumen)
      • Absence of lymphatic vessels (present in the muscularis mucosae)

    Sub-mucosal

    • Contains secreory glands, vascular capillaries, lymphatic vessels, and nodules

    Muscularis Externa

    • Made of smooth muscles in 2-layers (inner circular and outer longitudinal)
    • The outer longitudinal layer has teniae coli and the saccules (Haustra) that become prominent during colon contractions
    • Colon is capable of segmental contraction which does not affect the contents unlike peristalsis

    Serosal

    • Made of simple squamous epithelium (mesothelium) and a small amount of connective tissue
    • Absent where the intestine is attached to adjoining structures

    Cecum and Appendix

    • Cecum is the blind pouch distal to the ileocecal valves and the appendix is the finger-like projection of the cecum
    • Cecum has the same histology as the colon
    • Muscularis externa of the appendix has no inner circular layer, only longitudinal which is smooth
    • Abundance of lymphatic nodes that extend into the sub-mucosa

    Rectum and Anal Canal

    • Rectum is the dilated distal portion of the alimentary canal
    • Mucosa is like that of the distal colon having straight tubular intestinal glands with many Goblet cells
    • The other layers are typical of the colon
    • No Teniae coli in the rectum

    Characteristics of Small Intestine

    • Lymphatic follicles: solitary lymphatic follicles are 1-2 mm in diameter, and aggregated lymphatic follicles or Peyer's patches form circular or oval patches
    • Large surface area:
      • Great length of the intestine
      • Presence of circular folds of mucous membrane
      • Villi and microvilli
    • Intestinal glands or crypts of Lieberkuhn:
      • Simple tubular glands distributed over the entire mucous membrane of the jejunum and ileum
      • Secrete digestive enzymes and mucus

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    Description

    This quiz covers the parts and characteristics of the large intestine, including the cecum, colon, rectum, and anal canal. Learn about the 4-layer characteristics and adaptations of the large intestine.

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