chapter 11. quiz 1. Anatomy of Cerebral Circulation
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Questions and Answers

how blood drains into the right and left internal jugular veins?

  • by 3 sets of veins
  • by 2 sets of veins
  • by collateral veins (correct)
  • by deep veins

In how many patients is the flow in the right internal jugular vein greater than in the left?

  • Approximately 50%
  • Approximately 65% (correct)
  • Approximately 30%
  • Approximately 40%

What may have implications for the insertion of jugular venous catheters for measuring jugular venous oxygen saturation?

  • Veins within the pia mater
  • Considerable asymmetry in blood flow between internal jugular veins (correct)
  • Asymmetry in arterial blood flow
  • Variability in the anatomy of the circle of Willis

Where are the superficial cortical veins located?

<p>On the brain's surface within the pia mater (D)</p> Signup and view all the answers

What shows substantial variability in its anatomy and a significant proportion may be incomplete?

<p>Circle of Willis (A)</p> Signup and view all the answers

Which vein is advocated as the dominant one for accurate measurement of jugular venous oxygen saturation through catheter insertion?

<p>Right internal jugular vein (D)</p> Signup and view all the answers

Which arteries make up the anterior circulation in the brain?

<p>Internal carotid arteries (C)</p> Signup and view all the answers

What is formed by connecting the two vertebral arteries?

<p>Basilar artery (D)</p> Signup and view all the answers

What is the purpose of the circle of Willis in the brain?

<p>To allow collateral circulation (C)</p> Signup and view all the answers

Which vessels connect to form a vascular loop at the base of the brain?

<p>internal carotid arteries and basilar artery (B)</p> Signup and view all the answers

What happens under normal circumstances regarding blood admixing in the anterior and posterior circulations?

<p>Equal pressures prevent blood admixing (A)</p> Signup and view all the answers

In pathologic circumstances with occlusion, what role can the circle of Willis play?

<p>To provide collateral circulation (B)</p> Signup and view all the answers

Which arteries make up the posterior circulation in the brain?

<p>Vertebral arteries (A)</p> Signup and view all the answers

which artery complete the loop of the circle of Willis

<p>posterior and the anterior communicating artery (A)</p> Signup and view all the answers

how many arteries that originate from the circle of Willis perfuse the brain

<p>3 paired arteries (C)</p> Signup and view all the answers

which circulations contribute more to the circle of Willis.

<p>anterior and the posterior circulations contribute equally (A)</p> Signup and view all the answers

How is cerebrospinal fluid (CSF) primarily produced in the brain?

<p>By choroid plexus (B)</p> Signup and view all the answers

What is the main route for CSF reabsorption?

<p>arachnoid granulations (D)</p> Signup and view all the answers

Which factor influences the daily production of CSF?

<p>Circadian rhythm, with peak production during sleep (C)</p> Signup and view all the answers

What is the approximate total daily production of CSF?

<p>$450$ mL (A)</p> Signup and view all the answers

In what manner does a smaller proportion of CSF gain access to the cerebral venous system?

<p>By transependymal flow (C)</p> Signup and view all the answers

What concept has been advanced recently as a means of waste product removal from the brain?

<p>Glymphatic pathway (A)</p> Signup and view all the answers

What effect do volatile anesthetic agents have on glymphatic transport?

<p>Reduce it (D)</p> Signup and view all the answers

Which brain region has approximately 4 times greater local cerebral blood flow and cerebral metabolic rate compared to white matter?

<p>Gray matter (B)</p> Signup and view all the answers

What percentage of the brain's energy consumption is dedicated to supporting electrophysiologic function?

<p>Approximately 60% (A)</p> Signup and view all the answers

What role do glial cells play in brain function?

<p>Maintaining the blood-brain barrier (A)</p> Signup and view all the answers

Which area within the brain has the highest oxygen consumption rate at rest?

<p>Gray matter (D)</p> Signup and view all the answers

What physiological mechanism ensures that blood flow in the brain is not excessive?

<p>Elaborate regulatory mechanisms (A)</p> Signup and view all the answers

What part of the brain is responsible for about 20% of total body oxygen utilization?

<p><strong>Whole-brain oxygen consumption</strong> (B)</p> Signup and view all the answers

During which states is glymphatic transport and waste clearance increased?

<p><strong>Sleep and general anesthesia</strong> (A)</p> Signup and view all the answers

'Approximately 60% of the brain’s energy consumption supports electrophysiologic function.' What makes up the remaining energy consumption?

<p><strong>Cellular homeostatic activities</strong> (B)</p> Signup and view all the answers

What is the glymphatic system's primary function within the brain?

<p>Waste disposal system (A)</p> Signup and view all the answers

peak production of CSF occurs during?

<p>sleep (B)</p> Signup and view all the answers

glymphatic pathway is a system which remove waste products from the brain. CSF enters the periarterial space and then the brain parenchyma. how this process is facilitated?

<p>by Aquaporin channels on the end-feet of astrocytes. (A)</p> Signup and view all the answers

CSF production is the result of

<p>hydrostatic efflux from capillaries into the perivascular space, and then active transport into the ventricles. (B)</p> Signup and view all the answers

which anesthetic drug has the least effect on glymphatic transport

<p>dexmedetomidine (B)</p> Signup and view all the answers

Anesthetic drugs cause

<p>dose-related and reversible alterations in cerebral physiology (A)</p> Signup and view all the answers

What percentage of total body oxygen utilization is represented by whole-brain oxygen consumption?

<p>20% (D)</p> Signup and view all the answers

What is the average oxygen consumption rate per 100g of brain tissue at rest?

<p>3.5 mL (D)</p> Signup and view all the answers

What is the range for global cerebral blood flow (CBF) in mL/100g/min?

<p>45-55 (B)</p> Signup and view all the answers

What is the range for the cerebral metabolic rate of oxygen (CMRO2) in mL/100g/min?

<p>3.0-3.5 (C)</p> Signup and view all the answers

What is the range for cerebrovascular resistance (CVR) in mm Hg/100 g/min/mL?

<p>1.5-2 (A)</p> Signup and view all the answers

What percentage of total body oxygen utilization is represented by whole-brain oxygen consumption?

<p>20% (D)</p> Signup and view all the answers

What is the range for global cerebral blood flow (CBF) in mL/100g/min?

<p>45-55 mL/100 g/min. (A)</p> Signup and view all the answers

What is the approximate range for the blood flow rate in the subcortical (mostly white matter) ?

<p>8-20 mL/100 g/min (A)</p> Signup and view all the answers

What is the range for cerebrovascular resistance (CVR) in mm Hg/100 g/min/mL?

<p>1.5-2.0 (B)</p> Signup and view all the answers

What is the approximate range for the cortical cerebral blood flow (CBF) in mL/100g/min?

<p>75-80 mL/100 g/min (B)</p> Signup and view all the answers

adult brain weighs approx ?

<p>Approximately 1350 g, Approximately 2% of total body weight (A)</p> Signup and view all the answers

how much adult brain receive from the total cardiac output?

<p>12% to 15% (A)</p> Signup and view all the answers

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