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Analgesics and Pain Management

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Questions and Answers

What is the primary purpose of opioid analgesics?

Relieve mild to moderate pain

Relieve acute pain (correct)

Reduce inflammation

Relieve chronic pain

Which neurotransmitters do endogenous opioids act on in the central nervous system (CNS)?

Serotonin

Dopamine

Acetylcholine

Endorphins & enkephalins (correct)

How do opioid analgesics produce their analgesic effects?

By acting on GABA receptors

By impeding neuronal firing and transmitter release (correct)

By increasing presynaptic calcium influx

By reducing postsynaptic potassium efflux

Which opioid analgesic is primarily an agonist on the Mu receptor present in the central nervous system (CNS), gastrointestinal tract (GIT), and peripheral tissues?

Codeine Signup and view all the answers

What is the main effect of morphine on the body?

Relief of pain without loss of consciousness Signup and view all the answers

What is the primary mechanism of action for NSAIDs?

Inhibition of cyclooxygenase (COX) enzymes, leading to decreased prostaglandin synthesis Signup and view all the answers

Which enzyme is inhibited by NSAIDs to reduce the synthesis of prostaglandins that cause pain and inflammation?

Cyclooxygenase (COX) Signup and view all the answers

Which enzyme is responsible for the synthesis of housekeeping prostaglandins that protect the gastric mucosa and maintain normal kidney function?

Cyclooxygenase (COX)-1 Signup and view all the answers

What is the primary difference between COX-1 and COX-2 enzymes?

COX-1 synthesizes prostaglandins causing pain and inflammation, while COX-2 synthesizes housekeeping prostaglandins Signup and view all the answers

Which of the following are common side effects associated with NSAIDs?

Gastric ulcer and renal failure Signup and view all the answers

Analgesics and Pain Management

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Podcast

Questions and Answers

What is the primary purpose of opioid analgesics?

Which neurotransmitters do endogenous opioids act on in the central nervous system (CNS)?

How do opioid analgesics produce their analgesic effects?

Which opioid analgesic is primarily an agonist on the Mu receptor present in the central nervous system (CNS), gastrointestinal tract (GIT), and peripheral tissues?

What is the main effect of morphine on the body?

What is the primary mechanism of action for NSAIDs?

Which enzyme is inhibited by NSAIDs to reduce the synthesis of prostaglandins that cause pain and inflammation?

Which enzyme is responsible for the synthesis of housekeeping prostaglandins that protect the gastric mucosa and maintain normal kidney function?

What is the primary difference between COX-1 and COX-2 enzymes?

Which of the following are common side effects associated with NSAIDs?

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