Podcast
Questions and Answers
What is the primary purpose of opioid analgesics?
What is the primary purpose of opioid analgesics?
- Relieve mild to moderate pain
- Relieve acute pain (correct)
- Reduce inflammation
- Relieve chronic pain
Which neurotransmitters do endogenous opioids act on in the central nervous system (CNS)?
Which neurotransmitters do endogenous opioids act on in the central nervous system (CNS)?
- Serotonin
- Dopamine
- Acetylcholine
- Endorphins & enkephalins (correct)
How do opioid analgesics produce their analgesic effects?
How do opioid analgesics produce their analgesic effects?
- By acting on GABA receptors
- By impeding neuronal firing and transmitter release (correct)
- By increasing presynaptic calcium influx
- By reducing postsynaptic potassium efflux
Which opioid analgesic is primarily an agonist on the Mu receptor present in the central nervous system (CNS), gastrointestinal tract (GIT), and peripheral tissues?
Which opioid analgesic is primarily an agonist on the Mu receptor present in the central nervous system (CNS), gastrointestinal tract (GIT), and peripheral tissues?
What is the main effect of morphine on the body?
What is the main effect of morphine on the body?
What is the primary mechanism of action for NSAIDs?
What is the primary mechanism of action for NSAIDs?
Which enzyme is inhibited by NSAIDs to reduce the synthesis of prostaglandins that cause pain and inflammation?
Which enzyme is inhibited by NSAIDs to reduce the synthesis of prostaglandins that cause pain and inflammation?
Which enzyme is responsible for the synthesis of housekeeping prostaglandins that protect the gastric mucosa and maintain normal kidney function?
Which enzyme is responsible for the synthesis of housekeeping prostaglandins that protect the gastric mucosa and maintain normal kidney function?
What is the primary difference between COX-1 and COX-2 enzymes?
What is the primary difference between COX-1 and COX-2 enzymes?
Which of the following are common side effects associated with NSAIDs?
Which of the following are common side effects associated with NSAIDs?