Anaerobic Gram-Positive and Negative Bacilli: Clostridia and Spirochetes

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24 Questions

What is the characteristic feature of Clostridia?

They are anaerobic spore-forming Gram-positive bacilli

Which of the following Clostridia causes flaccid paralysis?

C. botulinum

What is the result of trauma to the region of infection in Actinomycosis?

Pathogenic proliferation of the organisms

What is the characteristic of the fluid in Actinomycosis diagnosis?

It has a granular texture

What is the treatment for Actinomycosis?

Penicillin

What is the characteristic of Actinomycetes?

They form filamentous branches

What is the characteristic of Lactobacillus that helps create an acidic environment in the vagina?

Ability to ferment glucose into lactic acid

What is the primary source of infection for Bacteroides, Prevotella, Fusobacterium, and Porphyromonas?

Endogenous source through mucosal damage

What is the characteristic of Bacteroides, Prevotella, Fusobacterium, and Porphyromonas that can aid in diagnosis?

Unique morphology of Gram negative anaerobic bacilli

What is the primary role of Lactobacillus in the human body?

Inhibiting growth of many bacterial species

What is the common presentation of infections caused by Bacteroides, Prevotella, Fusobacterium, and Porphyromonas?

Foul-smelling discharge and tissue necrosis

How should specimens be collected and transported for isolation of Bacteroides, Prevotella, Fusobacterium, and Porphyromonas?

Under strict anaerobic conditions

What is the characteristic shape of Treponema pallidum cells?

Slender, spiral filaments with regular coils

Why can Treponema pallidum not be seen by light microscopy?

Because of its high lipid content

How many Treponema pallidum organisms are required to produce infection?

Less than 10

What is the name of the lesions that occur in moist intertriginous areas during Secondary Syphilis?

Condylomata

How can Treponema pallidum be transmitted from mother to fetus?

Through the placenta

What is the characteristic dental feature of Congenital Syphilis?

Hutchinson teeth

What is the primary specimen used for direct smear examination in syphilis diagnosis?

Exudate from chancre

Which type of microscope is used to examine smears stained with fluorescein-labelled anti-treponemal antibodies?

Fluorescent microscope

What is the target of non-treponemal antigen tests in syphilis diagnosis?

Lipid antigens

Which test is used to detect specific antibodies directed against protein constituants of T. pallidum?

Fluorescent T. pallidum antibody absorption

What is the effect of treatment and recovery on non-treponemal antigen tests?

Becomes negative

What is the drug of choice in the treatment of syphilis?

Penicillin

Test your knowledge on anaerobic Gram-positive and negative bacilli, including Clostridia, which are spore-forming bacteria found in soil and normal intestinal flora. Learn about their role in disease pathogenesis and species identification. Also, explore Spirochetes, a type of bacteria with a unique spiral shape.

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