Amoxicillin and Cephalexin Overview

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Questions and Answers

What is the primary mechanism of action for amoxicillin?

  • Inhibit protein synthesis
  • Weaken and destroy cell walls (correct)
  • Disrupt metabolic pathways
  • Inhibit nucleic acid synthesis

Which of the following is a common adverse reaction to amoxicillin?

  • Excessive sleepiness
  • Weight loss
  • Hives or difficulty breathing (correct)
  • Increased appetite

Why should amoxicillin be administered with food?

  • For better absorption (correct)
  • To reduce the risk of superinfection
  • To avoid allergic reactions
  • To enhance its antibacterial properties

Which condition may occur as a result of antibiotic use, including amoxicillin?

<p>Candidiasis (A)</p> Signup and view all the answers

What effect does penicillin have on oral contraceptives?

<p>Causes them to be less effective (A)</p> Signup and view all the answers

What should a patient do if they experience vaginal itching after taking amoxicillin?

<p>Notify their healthcare provider (A)</p> Signup and view all the answers

What is a contraindication for taking amoxicillin?

<p>Severe renal impairment (C)</p> Signup and view all the answers

Which of the following infections is amoxicillin effective in treating?

<p>Urinary tract infections (D)</p> Signup and view all the answers

What should be monitored for a patient taking a beta-lactam antibiotic?

<p>Gastrointestinal symptoms (B)</p> Signup and view all the answers

Which of the following is a common adverse reaction to aztreonam?

<p>Thrombophlebitis at IV site (B)</p> Signup and view all the answers

Which of the following conditions represents a contraindication for taking a beta-lactam antibiotic?

<p>Allergy to PCN (C)</p> Signup and view all the answers

What should clients be instructed to avoid while taking beta-lactam antibiotics?

<p>Alcohol consumption (C)</p> Signup and view all the answers

What is a primary therapeutic use of aztreonam?

<p>Treatment of lower respiratory tract infections (A)</p> Signup and view all the answers

In which scenario should a healthcare provider be notified immediately while a patient is on beta-lactam antibiotics?

<p>Having difficulty breathing (B)</p> Signup and view all the answers

Which intervention is NOT recommended for a patient receiving aztreonam?

<p>Monitoring bacterial growth (B)</p> Signup and view all the answers

What should patients taking beta-lactam antibiotics report promptly to their healthcare provider?

<p>Water diarrhea or candida in the mouth (A)</p> Signup and view all the answers

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Study Notes

Amoxicillin

  • Broad-spectrum antibiotic
  • Weakens and destroys bacterial cell walls
  • Beta-lactam antibiotic
  • Treats ear, throat infections, UTIs
  • Adding clavulanic acid increases the spectrum of the antibiotic

Amoxicillin Adverse Reactions

  • Allergy (hives, anaphylaxis)
  • GI distress (diarrhea, nausea, vomiting)
  • Superinfection (Candida, C. diff)

Amoxicillin Interventions

  • Monitor GI symptoms
  • Administer with food
  • Report watery diarrhea
  • Report oral thrush (Candida)
  • Monitor for hives or difficulty breathing

Amoxicillin Client Instructions

  • Take at the start of a meal for best absorption
  • Notify provider for vaginal itching, burning, or discharge
  • If having difficulty breathing, call 911

Amoxicillin Contraindications/Precautions

  • Allergy to penicillin, procaine, or benzathine
  • Caution with severe renal impairment
  • Penicillin reduces the effectiveness of oral contraceptives

Cephalexin

  • Broad-spectrum antibiotic
  • Weakens and destroys bacterial cell walls
  • Beta-lactam antibiotic
  • Treats ear, throat infections, and UTIs
  • Similar uses and effects to penicillin

Cephalexin Adverse Reactions

  • Allergy
  • GI distress
  • Superinfection
  • Cross-sensitivity with penicillin allergy

Cephalexin Interventions

  • Assess for penicillin allergy
  • Monitor GI symptoms
  • Administer with food
  • Report watery diarrhea
  • Report Candida of the mouth
  • Monitor for hives and difficulty breathing

Cephalexin Client Instructions

  • Do not take with alcohol
  • Notify provider for vaginal itching, burning, or discharge
  • If having difficulty breathing, call 911.

Cephalexin Contraindications/Precautions

  • Allergy to penicillin
  • Milk protein allergy
  • Caution with renal failure or GI disease

Aztreonam

  • Narrow-spectrum antibiotic
  • Effective against aerobic gram-negative bacteria
  • Treats lower respiratory tract infections, UTIs, abdominal infections

Aztreonam Adverse Reactions

  • Thrombophlebitis at IV site
  • GI distress
  • Superinfections
  • Rash
  • Inhalation: Airway wheezing, pain

Aztreonam Interventions

  • Monitor IV site for pain, redness, swelling
  • Monitor respiratory status
  • Monitor bowel function
  • Monitor for hives or difficulty breathing

Aztreonam Client Instructions

  • IM: Given in large muscle
  • IV: Given slowly, Report pain in the IV
  • Inhaled: Use nebulizer TID

Aztreonam Contraindications/Precautions

  • Caution with allergy to penicillin or cephalosporins
  • Caution with decreased renal function
  • No safety data for pregnancy or lactation

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