Questions and Answers
What is Amlodipine also known as?
What is the classification of Amlodipine?
Antihypertensive
What are the indications for Amlodipine?
Management of hypertension, angina pectoris, and vasospastic angina.
How does Amlodipine work?
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What are the therapeutic effects of Amlodipine?
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The recommended route and dosage of Amlodipine is ___ milligrams once daily.
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What are some common adverse reactions of Amlodipine?
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What should be monitored during Amlodipine therapy?
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What is the pregnancy category of Amlodipine?
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Study Notes
Amlodipine Overview
- Amlodipine is marketed under the brand name Norvasc.
- It is classified as an antihypertensive medication.
Indications
- Utilized to manage hypertension, angina pectoris, and vasospastic angina (Prinzmetal's angina).
- Can be used alone or in conjunction with other antihypertensive agents.
Mechanism of Action
- Amlodipine inhibits calcium transport into myocardial and vascular smooth muscle cells.
- This action disrupts excitation-contraction coupling, leading to reduced contraction of these tissues.
Therapeutic Effects
- Results in systemic vasodilation, which lowers blood pressure (BP).
- Promotes coronary vasodilation, decreasing both the frequency and severity of angina attacks.
Route and Dosage
- Typical dosage ranges from 5 to 10 mg taken once daily.
- Initiate treatment at 2.5 mg/day for fragile patients or those already on other antihypertensives, increasing as tolerated.
Adverse Reactions
- Central nervous system effects: dizziness, fatigue.
- Cardiovascular effects: peripheral edema, angina, bradycardia, hypertension, palpitations.
- Gastrointestinal disturbances: gingival hyperplasia, nausea.
- Dermatological effects: blushing.
Nursing Implications
- Regular monitoring of blood pressure and pulse is essential before, during, and periodically after therapy.
- Periodic ECG monitoring is recommended during prolonged treatment.
- Evaluate intake and output ratios, daily weight, and assess for signs of heart failure and edema.
Patient Teaching
- Instruct patients to adhere strictly to the medication regimen and avoid excessive grape juice consumption.
- Teach proper pulse monitoring techniques and advise on slow position changes to prevent orthostatic hypotension.
- Encourage good dental hygiene and frequent dental check-ups.
Evaluation of Effectiveness
- Look for a decrease in blood pressure and frequency/severity of angina attacks.
- Monitor a reduction in the need for nitrate therapy and an increase in activity tolerance and overall well-being.
Pregnancy Risk
- Amlodipine is classified as a Category D medication, indicating potential risks during pregnancy.
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Description
This quiz consists of flashcards covering key concepts related to Amlodipine, also known as Norvasc. It includes definitions, classifications, indications, and actions of this antihypertensive medication. Perfect for students studying pharmacology or healthcare professionals revising their knowledge.
