Amino Acids and the Urea Cycle
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Questions and Answers

Which amino acid is not essential for humans?

  • Hydroxylysine
  • Lysine
  • Serine
  • Tyrosine (correct)
  • What is the function of hydroxylysine in protein synthesis?

  • It is involved in the formation of peptide bonds
  • It acts as a catalyst for protein synthesis
  • It is a target for ubiquitination
  • It is used to flag proteins for export from the cell (correct)
  • What is the classification of serine based on its R-group?

  • Aromatic
  • Aliphatic
  • Polar (correct)
  • Non-polar
  • Which amino acid is often added to animal feed due to its limiting nature?

    <p>Lysine</p> Signup and view all the answers

    What is the role of tyrosine hydroxylase in the brain?

    <p>It converts tyrosine to l-dopa</p> Signup and view all the answers

    Which amino acid is a precursor to serine, hydroxylysine, and methyllysine?

    <p>Lysine</p> Signup and view all the answers

    What is the function of serine in proteins?

    <p>It is a component of the catalytic triad of serine proteases</p> Signup and view all the answers

    Why is lysine often added to dietary supplements?

    <p>It is a limiting amino acid</p> Signup and view all the answers

    What is the role of the hydroxyl group in serine?

    <p>It is a target for phosphorylation</p> Signup and view all the answers

    Which amino acid is a precursor to several important cellular compounds?

    <p>Serine</p> Signup and view all the answers

    Study Notes

    Amino Acid Classification

    • Essential and non-essential amino acids are classified based on whether they can be synthesized by cells or need to be obtained from the diet.
    • This classification has little to do with the structure of amino acids.
    • Essential amino acids vary from one organism to another and even differ in humans, depending on whether they are adults or children.

    Amino Acid Chemistry

    • Amino acids are categorized based on the chemistry of their R-groups.
    • Different textbooks may have different names for the categories and may categorize the same amino acid differently.

    Post-Translational Modifications

    • After a protein is synthesized, amino acid side chains within it can be chemically modified.
    • Common modifications include phosphorylation of hydroxyl groups of serine, threonine, or tyrosine.
    • Other modifications include addition of fatty acids, isoprenoid groups, acetyl groups, methyl groups, iodine, carboxyl groups, or sulfates.

    Amino Acid Functions

    • Some amino acids are precursors of important compounds in the body, such as epinephrine, thyroid hormones, L-dopa, and dopamine (from tyrosine), serotonin (from tryptophan), and histamine (from histidine).
    • Amino acids serve as constituents of proteins, which are polymers of amino acids.

    Specific Amino Acids

    • Ornithine is a metabolic precursor of arginine and citrulline.
    • Citrulline is a metabolic byproduct and is sometimes used as a dietary supplement to reduce muscle fatigue.
    • Lysine is a precursor of important compounds, including serotonin, niacin, and the auxin phytohormone.
    • Tyrosine is a non-essential amino acid that is a target for phosphorylation in proteins and plays a role in signaling processes.
    • Serine is a precursor of many important cellular compounds, including purines, pyrimidines, sphingolipids, folate, and the amino acids glycine, cysteine, and tryptophan.

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    Description

    This quiz covers the classification of amino acids, including essential and non-essential amino acids, and their role in the urea cycle. Learn about the metabolism of ornithine, arginine, and citrulline, and how they interact in the body.

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