Amino Acid Transamination Process

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Questions and Answers

What is the role of pyridoxal phosphate in the transfer of alpha-amino group?

  • It forms a new amino acid
  • It acts as the acceptor of the alpha-amino group
  • It acts as the donor of the alpha-amino group (correct)
  • It forms pyridoxine phosphate and a keto acid

What is the final product of the transfer of the alpha-amino group?

  • Pyridoxal phosphate
  • A keto acid
  • A new amino acid (correct)
  • Pyridoxine phosphate

What is the function of the acceptor alpha-keto acid in the transfer of the alpha-amino group?

  • It forms pyridoxine phosphate
  • It acts as the donor of the alpha-amino group
  • It acts as the acceptor of the alpha-amino group (correct)
  • It forms a keto acid

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Study Notes

Transamination Reaction

  • Pyridoxal phosphate (PLP) plays a crucial role in the transfer of the alpha-amino group by forming a Schiff base with the amino acid, allowing the transfer of the amino group to the acceptor alpha-keto acid.
  • The final product of the transfer of the alpha-amino group is an alpha-keto acid, which is formed when the amino group is transferred to the acceptor alpha-keto acid.
  • The acceptor alpha-keto acid functions as a recipient of the alpha-amino group, forming a new amino acid and an alpha-keto acid as products of the transamination reaction.

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