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Alzheimer's Disease and Dementia

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What is the primary focus of AD biomarker research in CSF and brain tissues?

Studying the effects of oxidative stress

Analyzing the role of calcium homeostasis

Identifying markers of neuronal damage

Understanding β-amyloid metabolism (correct)

What is the goal of recent metabolomic research in AD biomarkers?

To understand the role of Apolipoprotein E gene APOEε4

To develop a cure for AD

To study the effects of lipid metabolism on AD

To identify prognostic indicators and elucidate biological mechanisms (correct)

What was the primary finding in the study evaluating metabolites in AD patients and control subjects?

Triglycerides and amines were increased in AD patients

Age and gender-dependent differences in β-amyloid levels

Age and gender-dependent differential metabolic expression (correct)

Sphingomyelin was decreased in AD patients

Which compound was identified as a regulatory marker and strong predictor for AD in the study?

<p>Lysophosphatidic acid (LPA) C18:2</p> Signup and view all the answers

What was the significance of the study's findings on Apolipoprotein E gene APOEε4-positive AD?

<p>It proposed oxidative stress compounds as regulatory markers for AD</p> Signup and view all the answers

Alzheimer's Disease and Dementia

Choose a study mode

Podcast

Questions and Answers

What is the primary focus of AD biomarker research in CSF and brain tissues?

What is the goal of recent metabolomic research in AD biomarkers?

What was the primary finding in the study evaluating metabolites in AD patients and control subjects?

Which compound was identified as a regulatory marker and strong predictor for AD in the study?

What was the significance of the study's findings on Apolipoprotein E gene APOEε4-positive AD?

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