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Questions and Answers
What is the major proteolytic fragment of C3 that becomes covalently attached to microbes and is able to recruit and activate downstream complement proteins on the microbial surface?
What is the major proteolytic fragment of C3 that becomes covalently attached to microbes and is able to recruit and activate downstream complement proteins on the microbial surface?
- C3b (correct)
- C5a
- C4b
- C3a
What is the process called when a microbe is coated with molecules that are recognized by receptors on phagocytes?
What is the process called when a microbe is coated with molecules that are recognized by receptors on phagocytes?
- Inflammation
- Opsonization (correct)
- Phagocytosis
- Lysis
What is the function of some proteolytic fragments of complement proteins, especially C5a and C3a, in host defense?
What is the function of some proteolytic fragments of complement proteins, especially C5a and C3a, in host defense?
- Cell lysis
- Inflammation (correct)
- Phagocytosis
- Opsonization
What triggers the alternative pathway of the complement system?
What triggers the alternative pathway of the complement system?
Which pathway of the complement system is initiated by a microbial product in the absence of antibody?
Which pathway of the complement system is initiated by a microbial product in the absence of antibody?
What is the function of activated complement proteins?
What is the function of activated complement proteins?
Flashcards
What is C3b?
What is C3b?
C3b is the major fragment that covalently binds to microbes, recruiting and activating other complement proteins.
What is opsonization?
What is opsonization?
Opsonization is the process where microbes are coated, enhancing phagocyte recognition and ingestion.
C5a and C3a function?
C5a and C3a function?
C5a and C3a induce inflammation, attracting immune cells to sites of infection.
Alternative pathway trigger?
Alternative pathway trigger?
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What is the lectin pathway?
What is the lectin pathway?
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Function of Activated Complement Proteins?
Function of Activated Complement Proteins?
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