Podcast
Questions and Answers
What disease did Lou Gehrig give his name to?
What disease did Lou Gehrig give his name to?
- Huntington's disease
- Amyotrophic lateral sclerosis (ALS) (correct)
- Parkinson's disease
- Multiple sclerosis
Where did Lou Gehrig deliver his famous speech?
Where did Lou Gehrig deliver his famous speech?
- Fenway Park
- Wrigley Field
- Yankee Stadium (correct)
- Dodger Stadium
What commonality did Lou Gehrig share with the men and women serving in the armed forces of the United States?
What commonality did Lou Gehrig share with the men and women serving in the armed forces of the United States?
- He was a war hero
- He served during the Persian Gulf War
- He served in multiple branches of the military
- He was at greater risk of developing ALS (correct)
What conclusion does existing evidence support regarding military service and ALS?
What conclusion does existing evidence support regarding military service and ALS?
What percentage of U.S. persons meeting the case definition for ALS reported service in the military?
What percentage of U.S. persons meeting the case definition for ALS reported service in the military?
Why does the fraction of ALS patients reporting military service appear to be disproportionately large?
Why does the fraction of ALS patients reporting military service appear to be disproportionately large?
What did a CDC report published in 2018 demonstrate about men in older age groups affected by ALS?
What did a CDC report published in 2018 demonstrate about men in older age groups affected by ALS?
What is the main goal of The ALS Association as mentioned in the text?
What is the main goal of The ALS Association as mentioned in the text?
What is the impact of ALS on patients as described in the text?
What is the impact of ALS on patients as described in the text?
What is a part of the same neurodegenerative disease spectrum as ALS?
What is a part of the same neurodegenerative disease spectrum as ALS?
What is the prognosis for a person diagnosed with ALS?
What is the prognosis for a person diagnosed with ALS?
What is the function of Riluzole, a drug approved for the treatment of ALS?
What is the function of Riluzole, a drug approved for the treatment of ALS?
What has the current research revealed about Riluzole's effects on ALS?
What has the current research revealed about Riluzole's effects on ALS?
What does Nuedexta consist of?
What does Nuedexta consist of?
What should research into ALS and the military NOT be conducted at the expense of?
What should research into ALS and the military NOT be conducted at the expense of?
What is The ALS Association advocating for, according to the text?
What is The ALS Association advocating for, according to the text?
What are The ALS Association and its local Chapters a central resource for?
What are The ALS Association and its local Chapters a central resource for?
What does the text imply about the impact of understanding the connection between ALS and military service?
What does the text imply about the impact of understanding the connection between ALS and military service?
What substances are military personnel more likely to come into contact with, which are thought to be linked to ALS?
What substances are military personnel more likely to come into contact with, which are thought to be linked to ALS?
Which group experienced the greatest risk of ALS according to the study conducted by Ronnie D. Horner, Ph.D.?
Which group experienced the greatest risk of ALS according to the study conducted by Ronnie D. Horner, Ph.D.?
What was the funding source for the study conducted by Robert Haley, M.D., of the University of Texas Southwestern Medical Center at Dallas?
What was the funding source for the study conducted by Robert Haley, M.D., of the University of Texas Southwestern Medical Center at Dallas?
What did the study conducted by Robert Haley, M.D., find about the incidence of ALS in young Gulf War veterans?
What did the study conducted by Robert Haley, M.D., find about the incidence of ALS in young Gulf War veterans?
What did the study led by Ronnie D. Horner, Ph.D., seek to determine?
What did the study led by Ronnie D. Horner, Ph.D., seek to determine?
Which factor has been suggested as playing a role in the higher incidence of ALS reported in military personnel?
Which factor has been suggested as playing a role in the higher incidence of ALS reported in military personnel?
What was a key finding of the study conducted by Ronnie D. Horner, Ph.D., regarding ALS risk in military personnel?
What was a key finding of the study conducted by Ronnie D. Horner, Ph.D., regarding ALS risk in military personnel?
What age group did the study conducted by Robert Haley, M.D., focus on in relation to ALS occurrence?
What age group did the study conducted by Robert Haley, M.D., focus on in relation to ALS occurrence?
What does the text suggest about military TBIs in relation to ALS incidence?
What does the text suggest about military TBIs in relation to ALS incidence?
"Despite not knowing what increases risk in military populations" - What does this statement suggest about our current understanding?
"Despite not knowing what increases risk in military populations" - What does this statement suggest about our current understanding?
What should be considered when attempting to define ALS risk in the military population?
What should be considered when attempting to define ALS risk in the military population?
What did the study by Robert Haley, M.D. find about the observed incidence of ALS in young Gulf War veterans?
What did the study by Robert Haley, M.D. find about the observed incidence of ALS in young Gulf War veterans?
What is the main purpose of Nuedexta, as mentioned in the text?
What is the main purpose of Nuedexta, as mentioned in the text?
How is Edaravone thought to confer its protective benefits for ALS patients?
How is Edaravone thought to confer its protective benefits for ALS patients?
What is the prevalence of ALS in 2013 and 2014, as mentioned in the text?
What is the prevalence of ALS in 2013 and 2014, as mentioned in the text?
What percentage of all ALS cases are hereditary, according to the text?
What percentage of all ALS cases are hereditary, according to the text?
What aspect of ALS does Edaravone not address, according to the text?
What aspect of ALS does Edaravone not address, according to the text?
What is a recognized risk factor for the development of sporadic ALS?
What is a recognized risk factor for the development of sporadic ALS?
What was the prevalence of ALS in 2004, according to the text?
What was the prevalence of ALS in 2004, according to the text?
What is the main purpose of Edaravone, as mentioned in the text?
What is the main purpose of Edaravone, as mentioned in the text?
What is a potential cause for sporadic ALS, as indicated in the text?
What is a potential cause for sporadic ALS, as indicated in the text?
What does Nuedexta primarily treat in ALS patients?
What does Nuedexta primarily treat in ALS patients?
What did the FDA approve Edaravone for?
What did the FDA approve Edaravone for?
What organization advised the federal government on public health issues and healthcare policy regarding ALS in veterans?
What organization advised the federal government on public health issues and healthcare policy regarding ALS in veterans?
When did the IOM issue the finding that the existing evidence supports an increased risk of ALS in veterans?
When did the IOM issue the finding that the existing evidence supports an increased risk of ALS in veterans?
What did the IOM note about the Harvard study on retrospective cohorts from all eras of service regarding ALS and the military?
What did the IOM note about the Harvard study on retrospective cohorts from all eras of service regarding ALS and the military?
What did the VA implement regulations for in 2008, two years after the IOM report?
What did the VA implement regulations for in 2008, two years after the IOM report?
How does the presumption for ALS differ from other presumptions issued by the VA?
How does the presumption for ALS differ from other presumptions issued by the VA?
What did the epidemiologists at Harvard's School of Public Health report in their studies published in 2009 and 2015 regarding the risk of ALS in men with a history of military service?
What did the epidemiologists at Harvard's School of Public Health report in their studies published in 2009 and 2015 regarding the risk of ALS in men with a history of military service?
What was one important aspect of the studies conducted by epidemiologists at Harvard’s School of Public Health?
What was one important aspect of the studies conducted by epidemiologists at Harvard’s School of Public Health?
What was the result of the meta-analysis conducted using eight case-control studies and three cohort studies to elucidate the relationship between military service and ALS?
What was the result of the meta-analysis conducted using eight case-control studies and three cohort studies to elucidate the relationship between military service and ALS?
What was one limitation mentioned about the meta-analysis conducted using case-control and cohort studies?
What was one limitation mentioned about the meta-analysis conducted using case-control and cohort studies?
What did the committee appointed by IOM call for after evaluating the existing scientific literature on ALS in the veteran population?
What did the committee appointed by IOM call for after evaluating the existing scientific literature on ALS in the veteran population?
What prompted the VA to request an independent assessment of the relationship between military service and ALS?
What prompted the VA to request an independent assessment of the relationship between military service and ALS?
Which study demonstrated that men who served in the military and were born between 1915-1939 had higher ALS mortality rates?
Which study demonstrated that men who served in the military and were born between 1915-1939 had higher ALS mortality rates?
What did the VA establish in 2006 to support research on ALS in veterans?
What did the VA establish in 2006 to support research on ALS in veterans?
What is the main purpose of the Genes and Environmental Exposures in Veterans with ALS study (GENEVA)?
What is the main purpose of the Genes and Environmental Exposures in Veterans with ALS study (GENEVA)?
What was unique about the ALS C.A.R.E project?
What was unique about the ALS C.A.R.E project?
What did Congress mandate in 2008, subsuming the 2003-2007 VA registry?
What did Congress mandate in 2008, subsuming the 2003-2007 VA registry?
What did researchers at Harvard University’s School of Public Health seek to assess?
What did researchers at Harvard University’s School of Public Health seek to assess?
What did the VA establish in response to studies linking ALS and service in the Gulf War?
What did the VA establish in response to studies linking ALS and service in the Gulf War?
What did researchers note about the increase in ALS mortality among men born between 1915-1939 who had served in the military?
What did researchers note about the increase in ALS mortality among men born between 1915-1939 who had served in the military?
What did studies demonstrate about Gulf War veterans concerning their likelihood to develop ALS?
What did studies demonstrate about Gulf War veterans concerning their likelihood to develop ALS?
What kind of data does the Million Veteran Program aim to provide?
What kind of data does the Million Veteran Program aim to provide?
What was unique about the findings reported in a 2009 publication regarding male patients with ALS?
What was unique about the findings reported in a 2009 publication regarding male patients with ALS?
What does the largest analysis to date on the ALS/military link suggest?
What does the largest analysis to date on the ALS/military link suggest?
What did the DVBIC research review find about the association between TBI and ALS?
What did the DVBIC research review find about the association between TBI and ALS?
What did researchers examine in relation to ALS and chronic traumatic encephalopathy (CTE)?
What did researchers examine in relation to ALS and chronic traumatic encephalopathy (CTE)?
Why did the DVBIC authors find the results inconclusive?
Why did the DVBIC authors find the results inconclusive?
What do epidemiologists believe about cohorts with specific toxic exposures, such as veterans with known exposure to burning agents?
What do epidemiologists believe about cohorts with specific toxic exposures, such as veterans with known exposure to burning agents?
What is the Defense and Veterans Brain Injury Center (DVBIC) part of?
What is the Defense and Veterans Brain Injury Center (DVBIC) part of?
What did recent studies examine in subjects with confirmed ALS from the VA Biorepository Brain Bank?
What did recent studies examine in subjects with confirmed ALS from the VA Biorepository Brain Bank?
Why are subgroup analyses for military occupational specialty, frequency, duration, duty station, or specific incidents considered appropriate?
Why are subgroup analyses for military occupational specialty, frequency, duration, duty station, or specific incidents considered appropriate?
What is the main purpose of the information papers published by the Defense and Veterans Brain Injury Center (DVBIC)?
What is the main purpose of the information papers published by the Defense and Veterans Brain Injury Center (DVBIC)?
What did recent large population-based case-control studies conducted in Denmark find about employment by the military?
What did recent large population-based case-control studies conducted in Denmark find about employment by the military?
Why do researchers from the VA want to examine possible links between ALS and chronic traumatic encephalopathy (CTE)?
Why do researchers from the VA want to examine possible links between ALS and chronic traumatic encephalopathy (CTE)?