10 Questions
Define ergot alkaloids and provide an example of a plant source from which they are derived.
Ergot alkaloids are a group of alkaloids derived from the parasitic fungus Claviceps purpurea, which grows in the ovaries of various cereal grasses, particularly rye and wheat.
Explain the two main structural types of ergot alkaloids and provide examples of each type.
The two main structural types of ergot alkaloids are clavine type alkaloids and lysergic acid amides. An example of a clavine type alkaloid is ergonovine, and an example of a lysergic acid amide is ergotamine.
What is the difference between members related to lysergic acid and those related to isolysergic acid, in terms of activity and optical rotation?
Members related to lysergic acid are levorotatory and more active, while members related to isolysergic acid are dextrorotatory and less active.
How are lysergic acid members converted to the corresponding isolysergic acid members?
Lysergic acid members are converted to the corresponding isolysergic acid members by refluxing their methanolic solutions with alcoholic KOH.
What is the plant source and structural type of the alkaloid ergonovine?
Ergonovine is derived from the parasitic fungus Claviceps purpurea and belongs to the clavine type alkaloids.
Which plant serves as the source for the parasitic fungus Claviceps purpurea, which produces ergot alkaloids?
Rye
Which type of ergot alkaloids are medicinally inactive due to the absence of a carboxylic group at C8?
Clavine type alkaloids
What is the suffix used for members related to lysergic acid, which are more active and levorotatory?
-ine
How are lysergic acid members converted to the corresponding isolysergic acid members?
Refluxing with alcoholic KOH
Which cereal grass serves as a host for the parasitic fungus Claviceps purpurea, leading to the production of ergot alkaloids?
Wheat
Test your knowledge of alkaloids with this quiz based on Dr. Hala M. Hammoda's Phytochemistry PPC303 lecture on Indole alkaloids. Identify alkaloids such as Ergot, Strychnos, Physostigma, Psilocin, Gelsemium, Vinca, Yohimbe, Harmala, and Rauwolfia alkaloids.
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