Alcohol Denaturation and Oxidation Reactions Quiz
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Questions and Answers

What can interfere with the absorption of fluoroquinolones?

  • Vitamin B12
  • Calcium supplements
  • Sucralfate (correct)
  • Vitamin C
  • Which antibacterial agents are contraindicated for pregnant women with UTI?

  • Tetracyclines
  • Fluoroquinolones (correct)
  • Aminoglycosides
  • Macrolides
  • Which adverse effect is NOT associated with fluoroquinolones?

  • Nephrotoxicity
  • Dizziness
  • Crystalluria
  • Dry mouth (correct)
  • What is the mechanism of action of fluoroquinolones?

    <p>Inhibition of DNA synthesis</p> Signup and view all the answers

    Which first-generation quinolone is useful in treating UTIs caused by Gram-negative bacteria?

    <p>Nalidixic acid</p> Signup and view all the answers

    What enzyme do fluoroquinolones inhibit to interfere with DNA synthesis?

    <p>Topoisomerase II (DNA gyrase)</p> Signup and view all the answers

    'Cinoxacin' (Cinobac®) shares the same action with 'Nalidixic acid' but has what advantage?

    <p>Greater oral bioavailability</p> Signup and view all the answers

    'Norfloxacin' (Noroxin) has a broad spectrum of activity against which types of bacteria?

    <p>Both Gram-negative &amp; Gram-positive bacteria</p> Signup and view all the answers

    What is the mechanism of action of sulfonamides?

    <p>Inhibition of dihydrofolate reductase</p> Signup and view all the answers

    Which drug combination is used as the first-line treatment for Pneumocystis carinii?

    <p>Trimethoprim and sulfamethoxazole</p> Signup and view all the answers

    Which type of leprosy is Dapsone (Avlosulfon) commonly used to treat?

    <p>Lepromatous leprosy</p> Signup and view all the answers

    Which sulfonamide drug is used in burn therapy to prevent and treat bacterial infection?

    <p>Silver sulfadiazine</p> Signup and view all the answers

    What adverse effect is commonly associated with sulfones like Dapsone?

    <p>Hemolytic anemia</p> Signup and view all the answers

    Which drug is used as a single agent for uncomplicated urinary tract infections?

    <p>Trimethoprim</p> Signup and view all the answers

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