Alcohol Denaturation and Oxidation Reactions Quiz
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Questions and Answers

What can interfere with the absorption of fluoroquinolones?

  • Vitamin B12
  • Calcium supplements
  • Sucralfate (correct)
  • Vitamin C

Which antibacterial agents are contraindicated for pregnant women with UTI?

  • Tetracyclines
  • Fluoroquinolones (correct)
  • Aminoglycosides
  • Macrolides

Which adverse effect is NOT associated with fluoroquinolones?

  • Nephrotoxicity
  • Dizziness
  • Crystalluria
  • Dry mouth (correct)

What is the mechanism of action of fluoroquinolones?

<p>Inhibition of DNA synthesis (A)</p> Signup and view all the answers

Which first-generation quinolone is useful in treating UTIs caused by Gram-negative bacteria?

<p>Nalidixic acid (D)</p> Signup and view all the answers

What enzyme do fluoroquinolones inhibit to interfere with DNA synthesis?

<p>Topoisomerase II (DNA gyrase) (A)</p> Signup and view all the answers

'Cinoxacin' (Cinobac®) shares the same action with 'Nalidixic acid' but has what advantage?

<p>Greater oral bioavailability (D)</p> Signup and view all the answers

'Norfloxacin' (Noroxin) has a broad spectrum of activity against which types of bacteria?

<p>Both Gram-negative &amp; Gram-positive bacteria (A)</p> Signup and view all the answers

What is the mechanism of action of sulfonamides?

<p>Inhibition of dihydrofolate reductase (A)</p> Signup and view all the answers

Which drug combination is used as the first-line treatment for Pneumocystis carinii?

<p>Trimethoprim and sulfamethoxazole (A)</p> Signup and view all the answers

Which type of leprosy is Dapsone (Avlosulfon) commonly used to treat?

<p>Lepromatous leprosy (C)</p> Signup and view all the answers

Which sulfonamide drug is used in burn therapy to prevent and treat bacterial infection?

<p>Silver sulfadiazine (D)</p> Signup and view all the answers

What adverse effect is commonly associated with sulfones like Dapsone?

<p>Hemolytic anemia (D)</p> Signup and view all the answers

Which drug is used as a single agent for uncomplicated urinary tract infections?

<p>Trimethoprim (B)</p> Signup and view all the answers

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