18 Questions
What is the approximate percentage of slowed vitamin D synthesis in people aged 65 years compared to younger adults?
75%
What is the projected change in the prevalence of Dementia by 2050?
It is expected to triple
What is a modifiable risk factor for Alzheimer's disease?
Mid-life obesity
What is a key component of a healthy diet that may help offset the risk of developing dementia?
Oily fish providing omega-3 fatty acids
What is the effect of increased ROS production on telomeres?
It causes telomere shortening
What is the estimated proportion of Alzheimer's disease cases attributable to modifiable risk factors?
One third
What is the primary source of ROS production within cells?
Mitochondria
What is the primary factor in immune dysregulation in older people?
Oxidative stress
What is the effect of caloric restriction on ROS production?
It decreases ROS production
What is associated with a reduced rate of telomere shortening?
Omega-3 fatty acids
What is the effect of a Mediterranean diet on telomere length?
It preserves telomere length
What is the effect of obesity on telomere length?
It decreases telomere length
What is the effect of calorie restriction on energy metabolism and ROS production?
It reduces energy metabolism and ROS production
What is the effect of calorie restriction on telomere length in rodents?
It has a positive effect
What is the term used to describe the age-related increase in pro-inflammatory markers in blood and tissues?
Inflammageing
What can reduce the rate of telomere shortening and extend health span?
Calorie restriction, healthy diet, and regular exercise
What is the result of impaired immunity in older people?
Multiple micronutrient deficiencies
What is the term used to describe the loss of ability to produce endogenous antioxidants in older people?
Immunosenescence
Test your knowledge on how aging is influenced by endogenous and exogenous factors, including lifestyle habits and environmental stress. Learn about the impact of ROS production and cellular defense mechanisms on aging.
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