African Swine Fever in Asfarviridae

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Questions and Answers

Which family does the African Swine Fever virus belong to?

Flaviviridae
Coronaviridae
Asfarviridae (correct)
Herpesviridae

What is unique about the African Swine Fever virus?

It is the only known RNA arbovirus
It is the only known DNA arbovirus (correct)
It has a double-stranded RNA genome
It only affects wild pigs

Which animals are considered reservoir hosts for African Swine Fever?

Domestic pigs and European wild boars
Cattle and sheep
Goats and camels
Warthogs, bush pigs, and giant forest hogs (correct)

African Swine Fever is classified as a/an:

OIE List A Disease (A) Signup and view all the answers

Where is African Swine Fever endemic?

Most of sub-Saharan Africa and Sardinia (Italy) (B) Signup and view all the answers

Which of the following countries has experienced recent outbreaks of African Swine Fever?

Eastern Europe and Russia Signup and view all the answers

What years saw a continued spread of African Swine Fever within the Russian Federation?

2009-2013 (B) Signup and view all the answers

How long can the African Swine Fever virus survive in pig pens?

30 days (C) Signup and view all the answers

What pH range can the ASF virus survive in for several hours?

4 to 13 (B) Signup and view all the answers

In which of the following can ASF virus remain viable for long periods?

All the above (D) Signup and view all the answers

How long can the ASF virus survive in a chilled pig carcass?

6 months (C) Signup and view all the answers

What property of ASF virus makes it highly resistant to decomposition?

It is highly resistant to putrefaction (B) Signup and view all the answers

Which of the following statements about ASF virus is true?

It causes hemadsorption (B) Signup and view all the answers

Which statement about hemadsorption in African Swine Fever (ASF) is correct?

Hemadsorption is caused by a virus-specific protein that appears on the plasma membrane of infected cells. (A) Signup and view all the answers

Hemadsorption: infected / adhere and eat _____

Monocytes/macrophages; RBCs Signup and view all the answers

What is the vector responsible for transmitting ASF virus?

Soft ticks (Ornithodoros sp.) (C) Signup and view all the answers

Which of the following is NOT a mode of ASF virus transmission in ticks?

Vertical transmission in pigs (D) Signup and view all the answers

How long can infected Ornithodoros ticks live and transmit ASF virus?

Several years (C) Signup and view all the answers

Which of the following best describes the sylvatic cycle of African Swine Fever (ASF) virus transmission?

Transmission between wild pigs and soft ticks, where wild pigs act as asymptomatic reservoirs. (B) Signup and view all the answers

How do young wild pigs contribute to the sylvatic cycle of ASF?

They develop viremia with high virus titers, allowing infection of feeding ticks. (C) Signup and view all the answers

Older wild pigs are persistently infected, but rarely develop viremia

True (A) Signup and view all the answers

Which of the following is NOT a mode of ASF transmission in domestic pigs?

Transmission via mosquito bites (D) Signup and view all the answers

Domestic pigs that survive infection may become and shed the virus in _ and _____

Carriers; secretions; excretions Signup and view all the answers

Primary outbreaks of ASF in domestic swine can result from direct contact with fomites

False (B) Signup and view all the answers

What is the primary pathological effect of ASF virus in infected pigs?

Hemorrhages and apoptosis (B) Signup and view all the answers

The pathogenesis of ASF include seeing conditions such as _, and _

Lymphopenia, leukopenia and thrombocytopenia Signup and view all the answers

Which viral protein is responsible for directly inducing apoptosis in host cells during ASF infection?

p54 (A) Signup and view all the answers

In apoptosis of host cells: ASF infected macrophages release and ____

Cytokines and apoptotic mediators Signup and view all the answers

Apoptosis of host cells with ASF virus include the cells _ and ___

Lymphocytes and mononuclear phagocytic cells Signup and view all the answers

Which of the following mechanisms contributes to hemorrhage in ASF-infected pigs?

All of the above (D) Signup and view all the answers

Thrombocytopenia and coagulation defects lead to :

Edema, infarction, exudation and hemorrhages in many organs and tissues Signup and view all the answers

Match the CS in domestic pigs to the correct description

Peracute = Sudden death Acute form = Fever, cyanotic blotching on the ears, tail lower legs or hams, diarrhea, abortion and death Chronic form = Emaciation, swollen joints, ulcers and reddened or raised necrotic skin foci and pneumonia Free bee = Free bee Signup and view all the answers

Redundant: What are the CS seen in the chronic form of ASF?

Emaciation and stunting, swollen joints, ulcers and reddened or raised necrotic skin foci and pneumonia Signup and view all the answers

In ___-skinned pigs, the _, and _ appear deeply flushed and may develop _____

In white-skinned pigs, the ears, tail and underside appear deeply flushed and may develop cyanosis Signup and view all the answers

In the chronic form, you may see an enlarged friable spleen, that is also called _____

BlackBerry jam spleen Signup and view all the answers

Why has vaccine development for African Swine Fever (ASF) been unsuccessful?

Virus-specific antibodies do not neutralize the virus effectively. (C) Signup and view all the answers

Which of the following is NOT an effective prevention strategy for ASF?

Feeding pigs uncooked swill containing pig remains. (B) Signup and view all the answers

How long should swill be boiled to ensure it is safe for pig consumption?

30 minutes (C) Signup and view all the answers

What is the FIRST action that must be taken if an ASF outbreak is suspected?

Immediately notify animal health authorities. (A) Signup and view all the answers

What should be done with infected or in-contact pigs during an ASF outbreak?

Slaughter and dispose of their carcasses by burning or deep burial on site. (D) Signup and view all the answers

How should farm personnel prevent the spread of ASF between farms?

All of the above. (D) Signup and view all the answers

Flashcards

ASF virus family?

Asfarviridae

Unique trait of ASF virus?

Only known DNA arbovirus