Aerosol Manufacture and Nebulizers

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5 Questions

What type of nebulizer is suitable for aerosolizing high-viscosity or high-surface-tension formulations?

Mesh nebulizers

Which of the following factors affects the performance of a nebulizer?

All of the above

What is a consideration for nebulizer formulation?

All of the above

What is a drawback of nebulizers?

All of the above

What is the effect of bolus volume on nebulizer performance in vivo?

Increased aerosol deposition

Study Notes

Aerosol Manufacture

  • Liquid droplet aerosols are a type of aerosol manufactured for therapeutic purposes.

Nebulizers

  • Nebulizers are a suitable therapeutic choice in certain situations.
  • There are three types of nebulizers: jet nebulizers, ultrasonic nebulizers, and mesh nebulizers.
  • Jet nebulizers use compressed gas to create aerosols.
  • Ultrasonic nebulizers use high-frequency sound waves to create aerosols.
  • Mesh nebulizers use a vibrating mesh to create aerosols.
  • Formulation considerations are important when using nebulizers, including factors such as particle size and distribution.
  • Performance and drawbacks of nebulizers vary, with some limitations including the effect of bolus and inhalation rate in vivo.

Learn about the different types of aerosol manufacture, including liquid droplet aerosols, and nebulizers, such as jet, ultrasonic, and mesh nebulizers.

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