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Adverse Cutaneous Drug Reactions: Case Study and Management

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Adverse Cutaneous Drug Reactions: Case Study and Management

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Questions and Answers

What is the characteristic presentation of urticaria?

Localised inflamed dark patches

Annular or polycyclic erythematous patches with central dusky areas

Mucous membrane erosions

Red, raised, itchy bumps (correct)

What is the primary treatment for fixed drug eruption?

Antibiotics and proper wound care

Stopping the offending drug (correct)

Systemic corticosteroids

Topical antihistamines

What is the main mechanism of drug-induced vasculitis?

Allergic reaction to antibiotics

Immune complex mediated (correct)

Direct toxicity to skin cells

Hypersensitivity reaction

What is the characteristic lesion of erythema multiforme?

Annular or polycyclic erythematous patches with central dusky areas Signup and view all the answers

What is the primary goal of management in drug-induced vasculitis?

Supporting systemic involvement Signup and view all the answers

What is the primary treatment for photodermatitis?

Avoiding the offending drug Signup and view all the answers

Which of the following medications is not likely to cause drug-induced photosensitive disorders?

Penicillin Signup and view all the answers

What is the primary characteristic of Acute Generalised Exanthematous Pustulosis (AGEP)?

Sudden onset of generalised tiny sterile pustules on erythematous skin Signup and view all the answers

Which of the following conditions is a severe adverse cutaneous drug reaction?

Toxic Epidermal Necrolysis (TEN) Signup and view all the answers

What is the focus of treatment for Toxic Epidermal Necrolysis (TEN) and Stevens-Johnson Syndrome (SJS)?

Supportive treatment and multidisciplinary team effort Signup and view all the answers

Which of the following is a characteristic of Stevens-Johnson Syndrome (SJS)?

Flu-like symptoms followed by a painful red or purplish rash Signup and view all the answers

What is the purpose of IV immunoglobulins in the treatment of Toxic Epidermal Necrolysis (TEN)?

To inhibit keratinocyte apoptosis Signup and view all the answers