Adverse Cutaneous Drug Reactions: Case Study and Management
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Questions and Answers

What is the characteristic presentation of urticaria?

  • Localised inflamed dark patches
  • Annular or polycyclic erythematous patches with central dusky areas
  • Mucous membrane erosions
  • Red, raised, itchy bumps (correct)

What is the primary treatment for fixed drug eruption?

  • Antibiotics and proper wound care
  • Stopping the offending drug (correct)
  • Systemic corticosteroids
  • Topical antihistamines

What is the main mechanism of drug-induced vasculitis?

  • Allergic reaction to antibiotics
  • Immune complex mediated (correct)
  • Direct toxicity to skin cells
  • Hypersensitivity reaction

What is the characteristic lesion of erythema multiforme?

<p>Annular or polycyclic erythematous patches with central dusky areas (B)</p> Signup and view all the answers

What is the primary goal of management in drug-induced vasculitis?

<p>Supporting systemic involvement (A)</p> Signup and view all the answers

What is the primary treatment for photodermatitis?

<p>Avoiding the offending drug (D)</p> Signup and view all the answers

Which of the following medications is not likely to cause drug-induced photosensitive disorders?

<p>Penicillin (C)</p> Signup and view all the answers

What is the primary characteristic of Acute Generalised Exanthematous Pustulosis (AGEP)?

<p>Sudden onset of generalised tiny sterile pustules on erythematous skin (C)</p> Signup and view all the answers

Which of the following conditions is a severe adverse cutaneous drug reaction?

<p>Toxic Epidermal Necrolysis (TEN) (B)</p> Signup and view all the answers

What is the focus of treatment for Toxic Epidermal Necrolysis (TEN) and Stevens-Johnson Syndrome (SJS)?

<p>Supportive treatment and multidisciplinary team effort (A)</p> Signup and view all the answers

Which of the following is a characteristic of Stevens-Johnson Syndrome (SJS)?

<p>Flu-like symptoms followed by a painful red or purplish rash (B)</p> Signup and view all the answers

What is the purpose of IV immunoglobulins in the treatment of Toxic Epidermal Necrolysis (TEN)?

<p>To inhibit keratinocyte apoptosis (A)</p> Signup and view all the answers

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