14 Questions
What was the significance of stem cells in 1999 according to Science magazine?
They were named 'Advancement of the Year' for their ability to differentiate into other tissue types
What is a key challenge hindering the use of embryonic stem cells in cell therapy and research?
Histocompatibility issues
Which type of stem cells do not face histocompatibility, safety, and concerns like their embryonic counterparts?
Adult stem cells
What is one key area where adult stem cells have been used in clinical studies on humans?
Stem cells obtained from bone marrow
What is the main difference between induced pluripotent stem cells (iPSCs) and adult stem cells?
iPSCs are derived from embryos, while adult stem cells are found in adult tissues.
What is one potential application of stem cell therapy mentioned in the text?
Regenerating functional organs to replace damaged ones.
What is a major challenge associated with transplanting stem cells into patients?
The risk of tumors forming due to undifferentiated cells.
Why do iPSCs provide a personalized approach to treatment?
Since they can be derived from a patient's own cells.
What is one ethical concern associated with using embryonic stem cells in research?
Questions about the sanctity of human life.
What was the common challenge hindering the use of embryonic stem cells in cell therapy and research?
Ethical dilemmas
Which characteristic of adult stem cells is still under investigation?
Plasticity
In which group of stem cells is the differentiation potential well characterized in mice and humans?
Embryo stem cells
What is the main source of stem cells used in numerous clinical trials in humans mentioned in the text?
Bone marrow
Why are histocompatibility, safety, and ethical issues hurdles for embryonic stem cell use?
Potential immune rejection
Explore the significant milestones in stem cell research, from the naming as 'Advancement of the Year' by Science magazine in 1999 to the creation of the first human embryonic stem cell line. Learn about the increasing number of research papers and new models in this evolving field.
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