Adrenergic Drug Quiz
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Questions and Answers

Which enzyme metabolizes catecholamines in the synaptic space?

  • Both COMT and MAO
  • Catechol-O-methyltransferase (COMT) (correct)
  • Neither COMT nor MAO
  • Monoamine oxidase (MAO)
  • Which type of receptors do catecholamines potently activate?

  • Neither α nor β receptors
  • α receptors
  • Both α and β receptors (correct)
  • β receptors
  • Which of the following is NOT a catecholamine?

  • Epinephrine
  • Norepinephrine
  • Isoproterenol
  • Phenylephrine (correct)
  • Which type of drugs are sympathomimetic amines that contain the 3,4-dihydroxybenzene group?

    <p>Catecholamines</p> Signup and view all the answers

    Which receptors have a higher potency for isoproterenol compared to epinephrine and norepinephrine?

    <p>β receptors</p> Signup and view all the answers

    Study Notes

    Enzyme and Metabolism

    • Catechol-O-methyltransferase (COMT) metabolizes catecholamines in the synaptic space, playing a critical role in neurotransmitter regulation.

    Receptors Activated by Catecholamines

    • Catecholamines, such as dopamine, norepinephrine, and epinephrine, potently activate adrenergic receptors, which are divided into alpha (α) and beta (β) types.

    Identification of Catecholamines

    • Catecholamines include dopamine, norepinephrine, and epinephrine; they are derived from tyrosine. A substance that does not fit this category, such as serotonin, is NOT classified as a catecholamine.

    Sympathomimetic Amines

    • Sympathomimetic amines containing the 3,4-dihydroxybenzene group are classified as catecholamines. This structural feature is crucial for their activity as neurotransmitters.

    Receptor Potency Comparison

    • Beta-adrenergic receptors, particularly β1 and β2 receptors, have higher potency for isoproterenol compared to epinephrine and norepinephrine, making isoproterenol a more effective agonist for these receptors.

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    Description

    Test your knowledge on adrenergic drugs and their functions with this quiz by Prof. Murat Oz from the Faculty of Pharmacy at Kuwait University. Learn about the comparative potencies of epinephrine, norepinephrine, and isoproterenol on α and β receptors. Explore the properties of sympathomimetic amines.

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