Adrenergic Agonists and Drug Effects
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Questions and Answers

What is the clinical effect of CLONIDINE, an α2 agonist?

  • Increases blood pressure through a peripheral mechanism
  • Decreases heart rate and cardiac output (correct)
  • Increases blood pressure through a central action
  • Relieves bronchoconstriction
  • How does DOBUTAMINE, a β1 agonist, affect the body?

  • Relieves bronchoconstriction
  • Increases heart rate and cardiac output (correct)
  • Causes renal and coronary vasodilation
  • Decreases heart rate and cardiac output
  • Which adrenergic agonist is used for the treatment of overactive bladder in adults?

  • Isoproterenol
  • Terbutaline
  • Mirabegron/Vibegron (correct)
  • Phenylephrine
  • What is the mechanism of action of EPHEDRINE and PHENYLPROPANOLAMINE?

    <p>Release previously stored norepinephrine</p> Signup and view all the answers

    At what doses does DOPAMINE cause renal and coronary vasodilation?

    <p>Low doses</p> Signup and view all the answers

    What is the precursor to norepinephrine?

    <p>Dopamine</p> Signup and view all the answers

    Which drug is a prototypic muscarinic antagonist?

    <p>Atropine</p> Signup and view all the answers

    What is the effect of muscarinic antagonists on the binding of acetylcholine to the muscarinic receptor?

    <p>Inhibition</p> Signup and view all the answers

    Which group of drugs increase the concentration of acetylcholine and affect the neuromuscular junction?

    <p>Cholinesterase inhibitors</p> Signup and view all the answers

    What is the primary effect of cholinesterase inhibitors in Myasthenia Gravis?

    <p>Muscle weakness</p> Signup and view all the answers

    Which drug is used for urinary retention and acts as a cholinergic agonist?

    <p>Bethanechol</p> Signup and view all the answers

    What is the primary mechanism of action of cholinergic antagonists like Atropine?

    <p>Block acetylcholine binding</p> Signup and view all the answers

    Which type of αblockers are reversible inhibitors of the α receptor?

    <p>Phentolamine</p> Signup and view all the answers

    Which αblocker is an irreversible inhibitor of the α receptor and is used in the treatment of pheochromocytomas?

    <p>Phenoxybenzamine</p> Signup and view all the answers

    Which of the following is a specific antagonist of the α1A receptor used in the symptomatic treatment of benign prostatic hypertrophy?

    <p>Tamsulosin</p> Signup and view all the answers

    What is the primary effect of β2 antagonists on smooth muscle?

    <p>Constriction</p> Signup and view all the answers

    Which class of drugs should be used with caution in diabetics due to their effects?

    <p>βBlockers</p> Signup and view all the answers

    Which type of βblockers are often referred to as cardioselective due to their action on β1 receptors?

    <p>Metoprolol</p> Signup and view all the answers

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