Adrenaline (Epinephrine) Pharmacokinetics
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Questions and Answers

Which receptor does adrenaline directly stimulate?

  • α and β receptors (correct)
  • Only β receptors
  • Only α receptors
  • Dopamine receptors
  • What is the fate of approximately 80% of adrenaline in the body?

  • Excretion in urine as VMA
  • Distribution to all tissues except CNS
  • Re-uptake (correct)
  • Metabolism by MAO and COMT
  • What effect does adrenaline have on the respiratory system?

  • No effect on the respiratory system
  • Increased respiratory rate only
  • Bronchoconstriction and bronchial congestion
  • Bronchodilatation and bronchial decongestion (correct)
  • Where is adrenaline metabolized in the body?

    <p>In the wall of intestine by MAO</p> Signup and view all the answers

    What effect does adrenaline have on the urinary system?

    <p>Wall relaxation and sphincter contraction</p> Signup and view all the answers

    Which type of adrenoceptor is almost inhibitory and acts as a presynaptic receptor in both central sympathetic neurons and peripheral nerves?

    <p>Alpha adrenoceptor</p> Signup and view all the answers

    Which adrenoceptor type is responsible for increasing renin release in the kidney and has postsynaptic and presynaptic actions at adrenergic nerve terminals?

    <p>Beta1 adrenoceptor</p> Signup and view all the answers

    Which receptor type is involved in relaxation of smooth muscles in blood vessels, bronchi, and uterus?

    <p>Beta2 adrenoceptor</p> Signup and view all the answers

    Which receptor type is almost excitatory and plays a role in piloerection, sweat gland activity, and contraction of the iris (mydriasis)?

    <p>Alpha1 adrenoceptor</p> Signup and view all the answers

    Which receptor type is involved in decreasing insulin release and lipolysis?

    <p>Alpha2 adrenoceptor</p> Signup and view all the answers

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