Adrenaline (Epinephrine) Pharmacokinetics

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Which receptor does adrenaline directly stimulate?

α and β receptors (correct)

Only β receptors

Only α receptors

Dopamine receptors

What is the fate of approximately 80% of adrenaline in the body?

Excretion in urine as VMA

Distribution to all tissues except CNS

Re-uptake (correct)

Metabolism by MAO and COMT

What effect does adrenaline have on the respiratory system?

No effect on the respiratory system

Increased respiratory rate only

Bronchoconstriction and bronchial congestion

Bronchodilatation and bronchial decongestion (correct)

Where is adrenaline metabolized in the body?

In the wall of intestine by MAO Signup and view all the answers

What effect does adrenaline have on the urinary system?

Wall relaxation and sphincter contraction Signup and view all the answers

Which type of adrenoceptor is almost inhibitory and acts as a presynaptic receptor in both central sympathetic neurons and peripheral nerves?

Alpha adrenoceptor Signup and view all the answers

Which adrenoceptor type is responsible for increasing renin release in the kidney and has postsynaptic and presynaptic actions at adrenergic nerve terminals?

Beta1 adrenoceptor Signup and view all the answers

Which receptor type is involved in relaxation of smooth muscles in blood vessels, bronchi, and uterus?

Beta2 adrenoceptor Signup and view all the answers

Which receptor type is almost excitatory and plays a role in piloerection, sweat gland activity, and contraction of the iris (mydriasis)?

Alpha1 adrenoceptor Signup and view all the answers

Which receptor type is involved in decreasing insulin release and lipolysis?

Alpha2 adrenoceptor Signup and view all the answers

Adrenaline (Epinephrine) Pharmacokinetics

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Questions and Answers

Which receptor does adrenaline directly stimulate?

What is the fate of approximately 80% of adrenaline in the body?

What effect does adrenaline have on the respiratory system?

Where is adrenaline metabolized in the body?

What effect does adrenaline have on the urinary system?

Which type of adrenoceptor is almost inhibitory and acts as a presynaptic receptor in both central sympathetic neurons and peripheral nerves?

Which adrenoceptor type is responsible for increasing renin release in the kidney and has postsynaptic and presynaptic actions at adrenergic nerve terminals?

Which receptor type is involved in relaxation of smooth muscles in blood vessels, bronchi, and uterus?

Which receptor type is almost excitatory and plays a role in piloerection, sweat gland activity, and contraction of the iris (mydriasis)?

Which receptor type is involved in decreasing insulin release and lipolysis?

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