Adrenaline (Epinephrine) Pharmacokinetics
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Questions and Answers

Which receptor does adrenaline directly stimulate?

  • α and β receptors (correct)
  • Only β receptors
  • Only α receptors
  • Dopamine receptors

What is the fate of approximately 80% of adrenaline in the body?

  • Excretion in urine as VMA
  • Distribution to all tissues except CNS
  • Re-uptake (correct)
  • Metabolism by MAO and COMT

What effect does adrenaline have on the respiratory system?

  • No effect on the respiratory system
  • Increased respiratory rate only
  • Bronchoconstriction and bronchial congestion
  • Bronchodilatation and bronchial decongestion (correct)

Where is adrenaline metabolized in the body?

<p>In the wall of intestine by MAO (D)</p> Signup and view all the answers

What effect does adrenaline have on the urinary system?

<p>Wall relaxation and sphincter contraction (B)</p> Signup and view all the answers

Which type of adrenoceptor is almost inhibitory and acts as a presynaptic receptor in both central sympathetic neurons and peripheral nerves?

<p>Alpha adrenoceptor (A)</p> Signup and view all the answers

Which adrenoceptor type is responsible for increasing renin release in the kidney and has postsynaptic and presynaptic actions at adrenergic nerve terminals?

<p>Beta1 adrenoceptor (B)</p> Signup and view all the answers

Which receptor type is involved in relaxation of smooth muscles in blood vessels, bronchi, and uterus?

<p>Beta2 adrenoceptor (C)</p> Signup and view all the answers

Which receptor type is almost excitatory and plays a role in piloerection, sweat gland activity, and contraction of the iris (mydriasis)?

<p>Alpha1 adrenoceptor (A)</p> Signup and view all the answers

Which receptor type is involved in decreasing insulin release and lipolysis?

<p>Alpha2 adrenoceptor (D)</p> Signup and view all the answers

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