Adjunctive Effect of Grafting Biomaterials in Periodontal Treatment

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5 Questions

Which treatment showed a weighted mean difference of 1.40 mm in CAL change?

Hydroxyapatite

What was the range of CAL change difference between test and control groups?

-1.45 mm to 1.40 mm

What was the conclusion regarding the use of specific biomaterials/biologicals compared to OFD?

More effective in improving attachment levels

What was the result of the meta-analysis for bioactive glass?

Weighted mean difference 1.04 mm; 95% CI: 0.31–1.76

What was the observed heterogeneity in results between studies for most biomaterials/biologicals?

Highly statistically significant

Study Notes

Treatment Comparison

  • Bioactive glass treatment showed a weighted mean difference of 1.40 mm in Clinical Attachment Level (CAL) change.

CAL Change Difference

  • The range of CAL change difference between test and control groups was noted.

Biomaterials/Biologicals vs OFD

  • Conclusion: No significant difference was found in the use of specific biomaterials/biologicals compared to Open-Flap Debridement (OFD).

Meta-Analysis for Bioactive Glass

  • Result: A significant effect was observed in the meta-analysis for bioactive glass.

Heterogeneity in Results

  • Most biomaterials/biologicals showed significant heterogeneity in results between studies, making it challenging to draw conclusions.

Test your knowledge on the adjunctive effect of grafting biomaterials/biological agents with open flap debridement (OFD) in the treatment of deep intraosseous defects. This quiz covers the background, objectives, and methods of a systematic review of randomized controlled trials.

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